The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
How MAP Kinases Are Regulated
Open accessAbstract
The closely related MAP kinases,1(1) extracellular signal-regulated protein kinases 1 and 2 (ERK1 and ERK2), are ubiquitous components of signal transduction pathways. ERK1 and ERK2 are activated by diverse extracellular stimuli and by protooncogene products that induce proliferation or enhance differentiation (reviewed in Refs. 1 and 2). MAP kinase phosphorylations have an impact on processes in the cytoplasm, the nucleus, the cytoskeleton, and the membrane. The variety of signals that conscript the MAP kinase pathway demonstrates that this cascade serves a myriad of purposes, and the consequences of its activation will depend on cellular context.
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Citations
Cites
Independent Human MAP-Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms
Dérijard, B., Raingeaud, J., Barrett, T., Wu, I.-H., Han, J., Ulevitch, R. J., & Davis, R. J. (1995) · Science · doi:10.1126/science.7839144 · Cited by 1,555
Atomic structure of the MAP kinase ERK2 at 2.3 A resolution
Zhang, F., Strand, A., Robbins, D., Cobb, M. H., & Goldsmith, E. J. (1994) · Nature · doi:10.1038/367704a0 · Cited by 592
Self-citation
Cited by
Ultrasensitivity in the mitogen-activated protein kinase cascade.
Huang, C. Y., & Ferrell, J. E. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.19.10078 · Cited by 1,186
The MEK/ERK cascade: From signaling specificity to diverse functions
Shaul, Y. D., & Seger, R. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.10.005 · Cited by 940
Molecular basis of the effects of shear stress on vascular endothelial cells
Li, Y.-S. J., Haga, J. H., & Chien, S. (2005) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2004.09.030 · Cited by 904
A conserved docking motif in MAP kinases common to substrates, activators and regulators
Tanoue, T., Adachi, M., Moriguchi, T., & Nishida, E. (2000) · Nature Cell Biology · doi:10.1038/35000065 · Cited by 816
Reactive Oxygen Species-Induced Activation of the MAP Kinase Signaling Pathways
McCubrey, J. A., LaHair, M. M., & Franklin, R. A. (2006) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.8.1775 · Cited by 803
Metadata
- Authors
- Cobb, M. H., & Goldsmith, E. J.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1995-06
- Volume
- 270
- Issue
- 25
- Pages
- 14843-14846
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2068502127
- Cited by
- 1,719
- References
- 2
- FWCI
- 41.92
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Cobb, M. H., & Goldsmith, E. J. (1995). How MAP Kinases Are Regulated. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.270.25.14843
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