A Mutation at Tyrosine 1062 in MEN2A-Ret and MEN2B-Ret Impairs Their Transforming Activity and Association with Shc Adaptor Proteins

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Items 101–184 of 184

1. Cell signalling and gene expression mediated by RET tyrosine kinase
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2. Biochemical and biological responses induced by coupling of Gab1 to phosphatidylinositol 3-kinase in RET-expressing cells
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3. Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
   Ning Shi, Sheng Ye, Mark G. Bartlam, Maojun Yang, Jing Wu, Yiwei Liu, Fei Sun, Xueqing Han, Xiaozhong Peng, Boqing Qiang et al. · 2004 · Journal of Biological Chemistry
4. Relative Expression of the RET9 and RET51 Isoforms in Human Pheochromocytomas
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5. Inhibition of Ret Oncogene Activity by the Protein Tyrosine Phosphatase SHP1
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6. Glial Cell Line-Derived Neurotrophic Factor Differentially Stimulates Ret Mutants Associated with the Multiple Endocrine Neoplasia Type 2 Syndromes and Hirschsprung’s Disease1
   Francesca Carlomagno, Rosa Marina Melillo, Roberta Visconti, Giuliana Salvatore, Gabriella De Vita, Giovanni Lupoli, Yanbin Yu, Shuqian Jing, Giancarlo Vecchio, Alfredo Fusco et al. · 1998 · Endocrinology
7. RET(MEN 2B) is active in the endoplasmic reticulum before reaching the cell surface
   Pia Runeberg‐Roos, Heikki T. Virtanen, Märt Saarma · 2007 · Oncogene
8. Activation of RET tyrosine kinase regulates interleukin-8 production by multiple signaling pathways
   Naoko Iwahashi, Hideki Murakami, Yuji Nimura, Masahide Takahashi · 2002 · Biochemical and Biophysical Research Communications
9. A complex additive model of inheritance for Hirschsprung disease is supported by both RET mutations and predisposing RET haplotypes
   Macarena Ruiz‐Ferrer, Raquel M. Fernández, Guillermo Antiñolo, Manuel López-Alonso, Charis Eng, Salud Borrego · 2006 · Genetics in Medicine
10. Implication of expression of GDNF/Ret signalling components in differentiation of bone marrow haemopoietic cells
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11. A New Germline Point Mutation in Ret Exon 8 (Cys 515 Ser) in a Family with Medullary Thyroid Carcinoma
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12. RET PLCγ Phosphotyrosine Binding Domain Regulates Ca2+ Signaling and Neocortical Neuronal Migration
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13. mGluR2/3 agonist LY379268, by enhancing the production of GDNF, induces a time-related phosphorylation of RET receptor and intracellular signaling Erk1/2 in mouse striatum
    Valentina Di Liberto, Giuseppa Mudò, Natale Belluardo · 2011 · Neuropharmacology
14. Differential requirement of Tyr1062 multidocking site by RET isoforms to promote neural cell scattering and epithelial cell branching
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15. Microsomal Prostaglandin E2 Synthase-1 Is Induced by Conditional Expression of RET/PTC in Thyroid PCCL3 Cells through the Activation of the MEK-ERK Pathway
    Efisio Puxeddu, Norisato Mitsutake, Jeffrey A. Knauf, Sonia Moretti, Hei W. Kim, Karen A. Seta, Diane E. Brockman, Leslie Myatt, David E. Millhorn, James A. Fagin · 2003 · Journal of Biological Chemistry
16. Oncoprotein Signaling Mediates Tumor-Specific Inflammation and Enhances Tumor Progression
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17. Analysis of DOK‐6 function in downstream signaling of RET in human neuroblastoma cells
    Ai Kurotsuchi, Yoshiki Murakumo, Mayumi Jijiwa, Kei Kurokawa, Yasutomo Itoh, Yoshinori Kodama, Takuya Kato, Atsushi Enomoto, Naoya Asai, Hiroko Terasaki et al. · 2010 · Cancer Science
18. Key role of Shc signaling in the transforming pathway triggered by Ret/ptc2 oncoprotein
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19. Thyroid Cancer: Role of RET and Beyond
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20. Calcium/Calmodulin-Dependent Protein Kinase II and Its Endogenous Inhibitor α in Medullary Thyroid Cancer
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21. Multiple Endocrine Neoplasia Type 2
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23. PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential
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24. Internalization of Glial Cell-Derived Neurotrophic Factor Receptor GFRα1 in the Absence of the Ret Tyrosine Kinase Coreceptor
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27. Phase I Study of the Farnesyltransferase Inhibitor BMS-214662 Given Weekly in Patients with Solid Tumors
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28. Anti-proliferative Effect and Action Mechanism of Dexamethasone in Human Medullary Thyroid Cancer Cell Line
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30. Receptor tyrosine kinases (RTKs)
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31. RET and EDNRB mutation screening in patients with Hirschsprung disease: Functional studies and its implications for genetic counseling
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33. Engineering the Recruitment of Phosphotyrosine Binding Domain-containing Adaptor Proteins Reveals Distinct Roles for RET Receptor-mediated Cell Survival
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36. HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell deathin vitroandin vivo
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37. Expression of GFRα1 receptor splicing variants with different biochemical properties is modulated during kidney development
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38. Expression of c-ret promotes morphogenesis and cell survival in mIMCD-3 cells
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39. Novel Human-Derived RET Fusion NSCLC Cell Lines Have Heterogeneous Responses to RET Inhibitors and Differential Regulation of Downstream Signaling
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40. Deciphering adaptor specificity in GFL‐dependent RET‐mediated proliferation and neurite outgrowth
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41. Evidence of Both Extra- and Intracellular Cysteine Targets of Protein Modification for Activation of RET Kinase
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44. Multiple Endocrine Neoplasia Type 2: Molecular Aspects
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45. New insights into Dok-4 PTB domain structure and function
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47. Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction
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