Oxidized Phosphatidylcholines That Modify Proteins

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

Bligh, E. G., & Dyer, W. J. (1959) · Canadian Journal of Biochemistry and Physiology · doi:10.1139/o59-099 · Cited by 54,751

Measurement of protein using bicinchoninic acid

Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., & Klenk, D. C. (1985) · Analytical Biochemistry · doi:10.1016/0003-2697(85)90442-7 · Cited by 18,482

Role of oxidized low density lipoprotein in atherogenesis.

Witztum, J. L., & Steinberg, D. H. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115499 · Cited by 2,675

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

Ylä‐Herttuala, S., Palinski, W., Rosenfeld, M. E., Parthasarathy, S., Carew, T. E., Butler, S. S., Witztum, J. L., & Steinberg, D. H. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114271 · Cited by 1,877

Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein.

Watson, A. D., Berliner, J. A., Hama, S. Y., Du, B. N. L., Faull, K. F., Fogelman, A. M., & Navab, M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118359 · Cited by 1,153

Separation of plasma lipoproteins by density-gradient ultracentrifugation

Redgrave, T. G., Roberts, D., & West, C. E. (1975) · Analytical Biochemistry · doi:10.1016/0003-2697(75)90488-1 · Cited by 1,101

Minimally modified low density lipoprotein stimulates monocyte endothelial interactions.

Berliner, J. A., Territo, M., Sevanian, A., Ramin, S., Kim, J. A., Bamshad, B., Esterson, M., & Fogelman, A. M. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114562 · Cited by 924

Malondialdehyde-Altered Protein Occurs in Atheroma of Watanabe Heritable Hyperlipidemic Rabbits

Haberland, M. E., Fong, D., & Cheng, L. (1988) · Science · doi:10.1126/science.2455346 · Cited by 748

Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein.

Navab, M., Imes, S., Hama, S. Y., Hough, G. P., Ross, L. A., Bork, R. W., Valente, A. J., Berliner, J. A., Drinkwater, D. C., & Laks, H. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115532 · Cited by 733

Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein.

Watson, A. D., Navab, M., Hama, S. Y., Sevanian, A., Prescott, S. M., Stafforini, D. M., McIntyre, T. M., Du, B. N. L., Fogelman, A. M., & Berliner, J. A. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117726 · Cited by 403

Role of Oxidative Modifications in Atherosclerosis

Stocker, R., & Keaney, J. F. (2004) · Physiological Reviews · doi:10.1152/physrev.00047.2003 · Cited by 2,651

Clinical Relevance of Biomarkers of Oxidative Stress

Frijhoff, J., Winyard, P. G., Žarković, N., Davies, S. S., Stocker, R., Cheng, D., Knight, A. R., Taylor, E., Oettrich, J., Ruskovska, T., et al. (2015) · Antioxidants and Redox Signaling · doi:10.1089/ars.2015.6317 · Cited by 918

Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017

Kinoshita, M., Yokote, K., Arai, H., Iida, M., Ishigaki, Y., Ishibashi, S., Umemoto, S., Egusa, G., Ohmura, H., Okamura, T., et al. (2018) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.gl2017 · Cited by 813

Platelet-Activating Factor and Related Lipid Mediators

Prescott, S. M., Zimmerman, G. A., Stafforini, D. M., & McIntyre, T. M. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.419 · Cited by 747

Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity

Shaw, P. X., Hörkkö, S., Chang, M.-K., Curtiss, L. K., Palinski, W., Silverman, G. J., & Witztum, J. L. (2000) · Journal of Clinical Investigation · doi:10.1172/jci8472 · Cited by 676

Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid–protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins

Hörkkö, S., Bird, D. A., Miller, E. R., Itabe, H., Leitinger, N., Subbanagounder, G., Berliner, J. A., Friedman, P., Dennis, E. A., Curtiss, L. K., et al. (1999) · Journal of Clinical Investigation · doi:10.1172/jci4533 · Cited by 559

Circulating Oxidized Low Density Lipoprotein Levels

Toshima, S., Hasegawa, A., Kurabayashi, M., Itabe, H., Takano, T., Sugano, J., SHIMAMURA, K., Kimura, J., Michishita, I., Suzuki, T., et al. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.10.2243 · Cited by 407

Lipid analysis by thin-layer chromatography—A review of the current state

Fuchs, B., Süß, R., Teuber, K., Eibisch, M., & Schiller, J. (2010) · Journal of Chromatography A · doi:10.1016/j.chroma.2010.11.066 · Cited by 378

Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases

Trpković, A., Resanović, I., Stanimirović, J., Radak, D. J., Mousa, S. A., Cenic-Milosevic, D., Jevremović, D., & Isenović, E. R. (2014) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408363.2014.992063 · Cited by 326

Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2022

Okamura, T., Tsukamoto, K., Arai, H., Fujioka, Y., Ishigaki, Y., Koba, S., Ohmura, H., Shoji, T., Yokote, K., Yoshida, H., et al. (2023) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.gl2022 · Cited by 345

Heme Oxygenase-1 Inhibits Atherosclerotic Lesion Formation in LDL-Receptor Knockout Mice

Ishikawa, K., Sugawara, D., Wang, X.-P., Suzuki, K., Itabe, H., Maruyama, Y., & Lusis, A. J. (2001) · Circulation Research · doi:10.1161/01.res.88.5.506 · Cited by 296

LDL Immunization Induces T-Cell–Dependent Antibody Formation and Protection Against Atherosclerosis

Zhou, X., Caligiuri, G., Hamsten, A., Lefvert, A. K., & Hansson, G. K. (2001) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.21.1.108 · Cited by 291

Hemodialysis Impairs Endothelial Function via Oxidative Stress

Miyazaki, H., Matsuoka, H., Itabe, H., Usui, M., Ueda, S., Okuda, S., & Imaizumi, T. (2000) · Circulation · doi:10.1161/01.cir.101.9.1002 · Cited by 231

The Membrane-type Collectin CL-P1 Is a Scavenger Receptor on Vascular Endothelial Cells

Ohtani, K., Suzuki, Y., Eda, S., Kawai, T., Kase, T., Keshi, H., Sakai, Y., Fukuoh, A., Sakamoto, T., Itabe, H., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103942200 · Cited by 217

The oxidative modification hypothesis of atherosclerosis: the comparison of atherogenic effects on oxidized LDL and remnant lipoproteins in plasma.

Nakajima, K., Nakano, T., & Tanaka, A. (2006) · Clinica chimica acta; international journal of clinical chemistry · doi:10.1016/j.cca.2005.12.013 · Cited by 205

Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibody levels in healthy subjects

Shoji, T., Nishizawà, Y., Fukumoto, M., SHIMAMURA, K., Kimura, J., Kanda, H., Emoto, M., Kawagishi, T., & Morii, H. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00218-x · Cited by 185

Oxidative modification of low-density lipoprotein and immune regulation of atherosclerosis

Matsuura, E., Kobayashi, K., TABUCHI, M., & LOPEZ, L. (2006) · Progress in Lipid Research · doi:10.1016/j.plipres.2006.05.001 · Cited by 183

Evidence for a Role of Phospholipid Oxidation Products in Atherogenesis

Berliner, J. A. (2001) · Trends in Cardiovascular Medicine · doi:10.1016/s1050-1738(01)00098-6 · Cited by 182

Oxidized phospholipids and isoprostanes in atherosclerosis

Witztum, J. L., & Berliner, J. A. (1998) · Current Opinion in Lipidology · doi:10.1097/00041433-199810000-00008 · Cited by 170

Measuring Circulating Oxidized Low-Density Lipoprotein to Evaluate Coronary Risk

Tsimikas, S., & Witztum, J. L. (2001) · Circulation · doi:10.1161/01.cir.103.15.1930 · Cited by 155

Biologically Active Oxidized Phospholipids

McIntyre, T. M., Zimmerman, G. A., & Prescott, S. M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.36.25189 · Cited by 154

Mass spectrometry analysis of oxidized phospholipids

Domingues, M. R., Reis, A., & Domingues, P. M. (2008) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2008.07.003 · Cited by 148

Oxidized Low-density Lipoproteins: What Is Understood and What Remains to Be Clarified.

Itabe, H. (2003) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.26.1 · Cited by 148

Measurement of Plasma Oxidized Low-Density Lipoprotein and its Clinical Implications

Itabe, H., & Ueda, M. (2007) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.14.1 · Cited by 147

Oxidative Modification of LDL: Its Pathological Role in Atherosclerosis

Itabe, H. (2008) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-008-8095-9 · Cited by 146

Localization of oxidized phosphatidylcholine in nonalcoholic fatty liver disease: Impact on disease progression

Ikura, Y., Ohsawa, M., Suekane, T., Fukushima, H., Itabe, H., Jomura, H., Nishiguchi, S., Inoue, T., Naruko, T., Ehara, S., et al. (2006) · Hepatology · doi:10.1002/hep.21070 · Cited by 145

The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and β 2 glycoprotein 1 (and other proteins)

Hörkkö, S., Miller, E. R., Branch, D. W., Palinski, W., & Witztum, J. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.19.10356 · Cited by 138

Oxidized phospholipids in the macula increase with age and in eyes with age-related macular degeneration.

Suzuki, M., Kamei, M., Itabe, H., Yoneda, K., Bando, H., Kume, N., & Tano, Y. (2007) · PubMed Central · Cited by 127

Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases

Ryan, B. J., Nissim, A., & Winyard, P. G. (2014) · Redox Biology · doi:10.1016/j.redox.2014.05.004 · Cited by 119

Raised plasma oxidised LDL in acute cerebral infarction

Uno, M. (2003) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.74.3.312 · Cited by 114

Inhibition of lipoprotein‐associated phospholipase A2 diminishes the death‐inducing effects of oxidised LDL on human monocyte‐macrophages

Carpenter, K. L. H., Dennis, I. F., Challis, I. R., Osborn, D. P., Macphee, C. H., Leake, D. S., Arends, M. J., & Mitchinson, M. J. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)02840-x · Cited by 114

Oxidized phospholipids as a new landmark in atherosclerosis

Itabe, H. (1998) · Progress in Lipid Research · doi:10.1016/s0163-7827(98)00009-5 · Cited by 100

Bioactive products of phospholipid oxidation: isolation, identification, measurement and activities

Subbanagounder, G., Watson, A. D., & Berliner, J. A. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(00)00233-1 · Cited by 99

Oxidation products of cholesteryl linoleate are resistant to hydrolysis in macrophages, form complexes with proteins, and are present in human atherosclerotic lesions

Hoppe, G., Ravandi, A., Herrera, D., Kuksis, A., & Hoff, H. F. (1997) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37418-6 · Cited by 97

C-reactive protein enhances IgG-mediated phagocyte responses and thrombocytopenia

Kapur, R., Heitink‐Pollé, K. M. J., Porcelijn, L., Bentlage, A. E. H., Bruin, M. C. A., Visser, R., Roos, D., Schasfoort, R. B. M., de Haas, M., van der Schoot, C. E., et al. (2014) · Blood · doi:10.1182/blood-2014-05-579110 · Cited by 94

Lectin‐like Oxidized Low‐density Lipoprotein Receptor‐1, a New Promising Target for the Therapy of Atherosclerosis?

Chen, X., Zhang, T., & Du, G. (2007) · Cardiovascular Drug Reviews · doi:10.1111/j.1527-3466.2007.00009.x · Cited by 87

Oxidized low-density lipoprotein as a biomarker of in vivo oxidative stress: From atherosclerosis to periodontitis

Itabe, H. (2012) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.11-00020r1 · Cited by 87

Is Plasma Oxidized Low-Density Lipoprotein, Measured With the Widely Used Antibody 4E6, an Independent Predictor of Coronary Heart Disease Among U.S. Men and Women?

Wu, T., Willett, W. C., Rifai, N., Shai, I., Manson, J. E., & Rimm, E. B. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.03.057 · Cited by 85

Foam cell formation containing lipid droplets enriched with free cholesterol by hyperlipidemic serum

Mori, M., Itabe, H., Higashi, Y., Fujimoto, Y., Shiomi, M., Yoshizumi, M., Ouchi, Y., & Takano, T. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31503-0 · Cited by 82

HIV-1 Vpr induces TLR4/MyD88-mediated IL-6 production and reactivates viral production from latency

Hoshino, S., Konishi, M., Mori, M., Shimura, M., Nishitani, C., Kuroki, Y., Koyanagi, Y., Kano, S., Itabe, H., & Ishizaka, Y. (2010) · Journal of Leukocyte Biology · doi:10.1189/jlb.0809547 · Cited by 86

The effect of oxidized phospholipids on phenotypic polarization and function of macrophages

Serbulea, V., DeWeese, D. E., & Leitinger, N. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.02.035 · Cited by 79

Separation of peroxidation products of diacyl‐phosphatidylcholines by reversed‐phase liquid chromatography–mass spectrometry

Reis, A., Domingues, M. R., Amado, F. M. L., Ferrer-Correia, A. J. V., & Domingues, P. M. (2004) · Biomedical Chromatography · doi:10.1002/bmc.429 · Cited by 73

Simple and practical sandwich-type enzyme immunoassay for human oxidatively modified low density lipoprotein using antioxidized phosphatidylcholine monoclonal antibody and antihuman apolipoprotein-B antibody

Kohno, H., Sueshige, N., Oguri, K., Izumidate, H., Masunari, T., Kawamura, M., Itabe, H., Takano, T., Hasegawa, A., & Nagai, R. (2000) · Clinical Biochemistry · doi:10.1016/s0009-9120(00)00065-5 · Cited by 73

Lipid peroxidation and decomposition — Conflicting roles in plaque vulnerability and stability

Parthasarathy, S., Litvinov, D. Y., Selvarajan, K., & Garelnabi, M. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2008.03.002 · Cited by 71

C-Reactive Protein and Annexin A5 Bind to Distinct Sites of Negatively Charged Phospholipids Present in Oxidized Low-Density Lipoprotein

van Tits, L., Graaf, J. D., Toenhake-Dijkstra, H., van Heerde, W. L., & Stalenhoef, A. F. H. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000157979.51673.2c · Cited by 71

Tandem mass spectrometry of intact oxidation products of diacylphosphatidylcholines: evidence for the occurrence of the oxidation of the phosphocholine head and differentiation of isomers

Reis, A., Domingues, P. M., Ferrer-Correia, A. J. V., & Domingues, M. R. (2004) · Journal of Mass Spectrometry · doi:10.1002/jms.751 · Cited by 62

Chronic Alcohol Exposure Increases Circulating Bioactive Oxidized Phospholipids

Yang, L., Latchoumycandane, C., McMullen, M. R., Pratt, B. T., Zhang, R., Papouchado, B. G., Nagy, L. E., Feldstein, A. E., & McIntyre, T. M. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.119982 · Cited by 61

Differential Effects of Glycolipid Biosynthesis Inhibitors on Ceramide‐Induced Cell Death in Neuroblastoma Cells

Bieberich, E., Freischütz, B., Suzuki, M., & Yu, R. K. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0721040.x · Cited by 61

Diagnostic implications of circulating oxidized low density lipoprotein levels as a biochemical risk marker of coronary artery disease

Suzuki, T., Kohno, H., Hasegawa, A., Toshima, S., Amaki, T., Kurabayashi, M., & Nagai, R. (2002) · Clinical Biochemistry · doi:10.1016/s0009-9120(02)00326-0 · Cited by 58

Radical peroxidation of palmitoyl-lineloyl-glycerophosphocholine liposomes: Identification of long-chain oxidised products by liquid chromatography–tandem mass spectrometry

Reis, A., Domingues, M. R., Amado, F. M. L., Ferrer-Correia, A. J. V., & Domingues, P. M. (2007) · Journal of Chromatography B · doi:10.1016/j.jchromb.2007.05.006 · Cited by 55

Vitamin E-bonded hemodialyzer improves neutrophil function and oxidative stress in patients with end-stage renal failure

Tsuruoka, S., Kawaguchi, A., Nishiki, K., Hayasaka, T., Fukushima, C., Sugimoto, K., Saito, T., & Fujimura, A. (2002) · American Journal of Kidney Diseases · doi:10.1053/ajkd.2002.29901 · Cited by 54

Mass spectrometry analysis of oxidized phosphatidylcholine and phosphatidylethanolamine

O’Donnell, V. B. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.07.018 · Cited by 53

Fragmentation study of short‐chain products derived from oxidation of diacylphosphatidylcholines by electrospray tandem mass spectrometry: identification of novel short‐chain products

Reis, A., Domingues, P. M., Ferrer-Correia, A. J. V., & Domingues, M. R. (2004) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.1686 · Cited by 50

Oxidative Modification of Lipoproteins

Arai, H. (2013) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-007-7920-4_9 · Cited by 47

Long-term cadmium exposure accelerates age-related mitochondrial changes in renal epithelial cells

Takaki, A., Jimi, S., Segawa, M., Hisano, S., Takebayashi, S., & Iwasaki, H. (2004) · Toxicology · doi:10.1016/j.tox.2004.06.005 · Cited by 47

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK‐AGE Project

Weber, D., Stuetz, W., Toussaint, O., Debacq-Chainiaux, F., Dollé, M. E. T., Jansen, E., Gonos, E. S., Franceschi, C., Sikora, E., Hervonen, A., et al. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/1401452 · Cited by 46

Formation of Lipid-Protein Adducts in Low-Density Lipoprotein by Fluxes of Peroxynitrite and Its Inhibition by Nitric Oxide

Trostchansky, A., Batthyány, C., Botti, H., Radí, R., Denicola, A., & Rubbo, H. (2001) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2001.2583 · Cited by 46

A redox-sensitive pathway mediates oxidized LDL-induced downregulation of insulin-like growth factor-1 receptor

Higashi, Y., Peng, T., Du, J., Sukhanov, S., Li, Y., Itabe, H., Parthasarathy, S., & Delafontaine, P. (2005) · Journal of Lipid Research · doi:10.1194/jlr.m400478-jlr200 · Cited by 45

Oxidized Phospholipids in Oxidized Low-Density Lipoprotein Reduce the Activity of Tissue Factor Pathway Inhibitor Through Association with Its Carboxy-Terminal Region

Ohkura, N., Hiraishi, S., Itabe, H., Hamuro, T., Kamikubo, Y., Takano, T., Matsuda, J., & Horie, S. (2004) · Antioxidants and Redox Signaling · doi:10.1089/1523086041361686 · Cited by 44

Atherosclerosis — do we know enough already to prevent it?

Narasimhulu, C. A., Fernández-Ruíz, I., Selvarajan, K., Jiang, X., Sengupta, B., Riad, A., & Parthasarathy, S. (2016) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2016.02.006 · Cited by 45

Lysosomal accumulation of oxidized phosphatidylcholine-apolipoprotein B complex in macrophages: intracellular fate of oxidized low density lipoprotein

Itabe, H., Suzuki, K., Tsukamoto, Y., Komatsu, R., Ueda, M., Mori, M., Higashi, Y., & Takano, T. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(00)00098-6 · Cited by 42

Antiphospholipid antibodies associated with alcoholic liver disease specifically recognise oxidised phospholipids

Rolla, R., Vay, D., Mottaran, E., Parodi, M., Vidali, M., Sartori, M., Rigamonti, C., Bellomo, G., & Albano, E. (2001) · Gut · doi:10.1136/gut.49.6.852 · Cited by 42

A systematic review of the effect of the Excebrane dialyser on biomarkers of lipid peroxidation

Sosa, M. A., Balk, E. M., Lau, J. S. M., Liangos, O., Balakrishnan, V. S., Madias, N. E., Pereira, B. J. G., & Jaber, B. L. (2006) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfl376 · Cited by 41

Distinguished effects of antiphospholipid antibodies and anti-oxidized LDL antibodies on oxidized LDL uptake by macrophages

Kobayashi, K., Tada, K., Itabe, H., Ueno, T., Liu, P.-H., Tsutsumi, A., Kuwana, M., Yasuda, T., Shoenfeld, Y., de Groot, P. G., et al. (2007) · Lupus · doi:10.1177/0961203307084170 · Cited by 40

Metabolism of Oxidized Phosphatidylcholines Formed in Oxidized Low Density Lipoprotein by Lecithin-Cholesterol Acyltransferase

Itabe, H., Hosoya, R., Karasawa, K., Jimi, S., Saku, K., Takebayashi, S., Imanaka, T., & Takano, T. (1999) · The Journal of Biochemistry · doi:10.1093/oxfordjournals.jbchem.a022416 · Cited by 39

Gold nanoparticle–antibody conjugates for specific extraction and subsequent analysis by liquid chromatography–tandem mass spectrometry of malondialdehyde-modified low density lipoprotein as biomarker for cardiovascular risk

Haller, E., Lindner, W. F., & Lämmerhofer, M. (2014) · Analytica Chimica Acta · doi:10.1016/j.aca.2014.12.024 · Cited by 38

Separation and Analysis of Peptides and Proteins

Hühmer, A. F. R., Aced, G. I., Perkins, M. D., Gürsoy, R. N., JOIS, D. S. S., Larive, C. K., Siahaan, T. J., & Schöneich, C. (1997) · Analytical Chemistry · doi:10.1021/a1970003s · Cited by 34

Antibodies against electronegative LDL inhibit atherosclerosis in LDLr-/- mice

Grosso, D. M., Ferderbar, S., Wanschel, A. C. B. A., Krieger, M. H., Higushi, M. L., & Abdalla, D. S. P. (2008) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2008001200007 · Cited by 31

Detection of Oxidized Phospholipid-protein Adducts Using Anti-15-Hydroperoxyeicosatetraenoic Acid-Modified Protein Antibody: Contribution of Esterified Fatty Acid–Protein Adduct to Oxidative Modification of LDL

Kato, Y., & Osawa, T. (1998) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1997.0519 · Cited by 28

Oxidized Phosphatidylcholine in AlveolarMacrophages in Idiopathic Interstitial Pneumonias

Yoshimi, N., Ikura, Y., Sugama, Y., Kayo, S., Ohsawa, M., Yamamoto, S., Inoue, Y., Hirata, K., Itabe, H., Yoshikawa, J., et al. (2005) · Lung · doi:10.1007/s00408-004-2525-0 · Cited by 27

Structural identification of phosphatidylcholines having an oxidatively shortened linoleate residue generated through its oxygenation with soybean or rabbit reticulocyte lipoxygenase

Tokumura, A., Sumida, T., Toujima, M., Kogure, K., Fukuzawa, K., Takahashi, Y., & Yamamoto, S. (2000) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)32038-1 · Cited by 27

Oxidised Low-Density Lipoprotein-Induced Platelet Hyperactivity—Receptors and Signalling Mechanisms

Berger, M., & Naseem, K. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23169199 · Cited by 31

Activation of phospholipase A2 by 1-palmitoyl-2-(9'-oxo-nonanoyl)-sn-glycero-3-phosphocholine in vitro.

Code, C., Mahalka, A., Bry, K., & Kinnunen, P. (2010) · Biochimica et Biophysica Acta · doi:10.1016/j.bbamem.2010.05.002 · Cited by 26

Time course-changes in phosphatidylcholine profile during oxidative modification of low-density lipoprotein

Sasabe, N., Keyamura, Y., Obama, T., Inoue, N., Masuko, Y., Igarashi, Y., Aiuchi, T., Kato, R., Yamaguchi, T., Kuwata, H., et al. (2014) · Lipids in Health and Disease · doi:10.1186/1476-511x-13-48 · Cited by 26

Lipidomic Profiling on Oxidized Phospholipids in Type 2 Diabetes Mellitus Model Zebrafish

Chen, Z., Zang, L., Wu, Y., Nakayama, H., Shimada, Y., Shrestha, R., Zhao, Y., Miura, Y., Chiba, H., Hui, S., et al. (2018) · Analytical Sciences · doi:10.2116/analsci.18p281 · Cited by 25

Regulation of platelet adhesion by oxidized lipoproteins and oxidized phospholipids

Hartwich, J., Dembinska-Kiec, A., Gruca, A., Motyka, M., Partyka, Ł., Skrzeczyńska, J., Bzowska, M., Pryjma, J. R., Huber, J., Leitinger, N., et al. (2002) · Platelets · doi:10.1080/09533710022149368 · Cited by 25

Circulating oxidized LDL, increased in patients with acute myocardial infarction, is accompanied by heavily modified HDL

Sawada, N., Obama, T., Koba, S., Takaki, T., Iwamoto, S., Aiuchi, T., Kato, R., Kikuchi, M., Hamazaki, Y., & Itabe, H. (2020) · Journal of Lipid Research · doi:10.1194/jlr.ra119000312 · Cited by 24

Lipid nitration and formation of lipid-protein adducts: biological insights

Trostchansky, A., & Rubbo, H. (2006) · Amino Acids · doi:10.1007/s00726-006-0426-7 · Cited by 24

The Significance of Oxidized Low-Density Lipoprotein in Body Fluids as a Marker Related to Diseased Conditions

Itabe, H., Kato, R., Sawada, N., Obama, T., & Yamamoto, M. (2018) · Current Medicinal Chemistry · doi:10.2174/0929867325666180307114855 · Cited by 23

Different Effects of Homocysteine and Oxidized Low Density Lipoprotein on Methylation Status in the Promoter Region of the Estrogen Receptor α Gene

Huang, Y., Peng, K., Su, J., Huang, Y., Xu, Y., & Wang, S. (2007) · Acta Biochimica et Biophysica Sinica · doi:10.1111/j.1745-7270.2007.00251.x · Cited by 23

Transfer and Enzyme-Mediated Metabolism of Oxidized Phosphatidylcholine and Lysophosphatidylcholine between Low- and High-Density Lipoproteins

Sawada, N., Obama, T., Mizuno, M., Fukuhara, K., Iwamoto, S., Aiuchi, T., Makiyama, T., & Itabe, H. (2020) · Antioxidants · doi:10.3390/antiox9111045 · Cited by 22

Appearance of cross linked proteins in human atheroma and rat pre-fibrotic liver detected by a new monoclonal antibody

Itabe, H., Jimi, S., Kamimura, S., Suzuki, K., Uesugi, N., Imanaka, T., Shijo, H., & Takano, T. (1998) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/s0925-4439(97)00069-0 · Cited by 22

Doxazosin, an α1-adrenergic antihypertensive agent, decreases serum oxidized LDL

Kinoshita, M. (2001) · American Journal of Hypertension · doi:10.1016/s0895-7061(00)01263-2 · Cited by 21

Mass spectrometry of complex lipids

Kuksis, A. (1998) · Springer eBooks · doi:10.1007/978-1-4613-1131-7_6 · Cited by 20

Oxidized Low Density Lipoprotein : The Occurrence and Metabolism in Circulation and in Foam Cells

Itabe, H., & Takano, T. (2000) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat1994.7.123 · Cited by 20

Inhibition of endothelium-dependent arterial relaxation by oxidized phosphatidylcholine

Rikitake, Y., Hirata, K., Kawashima, S., Inoue, N., Akita, H., Kawai, Y., Nakagawa, Y., & Yokoyama, M. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00453-0 · Cited by 20

Identification of free radicals of glycerophosphatidylcholines containing ω-6 fatty acids using spin trapping coupled with tandem mass spectrometry

Reis, A., Domingues, P. M., Ferrer-Correia, A. J. V., & Domingues, M. R. (2006) · Free Radical Research · doi:10.1080/10715760601118353 · Cited by 19

Global analysis of differentially expressed genes in oxidized LDL-treated human aortic smooth muscle cells

Sukhanov, S., Song, Y. H., & Delafontaine, P. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)00990-2 · Cited by 17

Lipidomic Analysis of Glycerolipid and Cholesteryl Ester Autooxidation Products

Kuksis, A., Suomela, J., Tarvainen, M., & Kallio, H. P. T. (2009) · Molecular Biotechnology · doi:10.1007/s12033-009-9146-z · Cited by 17

Oxidative Damage to Biomimetic Membrane Systems: In Situ Fe(II)/Ascorbate Initiated Oxidation and Incorporation of Synthetic Oxidized Phospholipids

Knobloch, J. J., Nelson, A. R. J., Köper, I., James, M., & McGillivray, D. J. (2015) · Langmuir · doi:10.1021/acs.langmuir.5b02458 · Cited by 16

Peptide-phospholipid cross-linking reactions: Identification of leucine enkephalin-alka(e)nal-glycerophosphatidylcholine adducts by tandem mass spectrometry

Reis, A., Domingues, P. M., Ferrer-Correia, A. J. V., & Domingues, M. R. (2006) · Journal of the American Society for Mass Spectrometry · doi:10.1016/j.jasms.2006.01.006 · Cited by 16

Identification by electrospray tandem mass spectrometry of spin‐trapped free radicals from oxidized 2‐oleoyl‐1‐palmitoyl‐ sn ‐glycero‐3‐phosphocholine

Reis, A., Domingues, P. M., Ferrer-Correia, A. J. V., & Domingues, M. R. (2004) · Rapid Communications in Mass Spectrometry · doi:10.1002/rcm.1444 · Cited by 15

Treatment B) Drug Therapy

Teramoto, T., Sasaki, J., Ishibashi, S., Birou, S., Daida, H., Dohi, S., Egusa, G., Hiro, T., Hirobe, K., Iida, M., et al. (2013) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.19166 · Cited by 13

A simple method to generate oxidized phosphatidylcholines in amounts close to one milligram

Zschörnig, K., & Schiller, J. (2014) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2014.09.003 · Cited by 11

Oxidized LDL and paraoxanase status in ischemic stroke patients.

Sarkar, P. D., & Rautaray, S. S. (2008) · PubMed · Cited by 11

Biomarkers in ROS and Role of Isoprostanes in Oxidative Stress

Chandra, M., Panchatcharam, M., & Miriyala, S. (2016) · InTech eBooks · doi:10.5772/64706 · Cited by 13

Development and Clinical Application of an Enzyme-Linked Immunosorbent Assay for Oxidized High-Density Lipoprotein

Okada, T., Sumida, M., Ohama, T., Katayama, Y., Saga, A., Inui, H., Kanno, K., Masuda, D., Koseki, M., Nishida, M., et al. (2020) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.56887 · Cited by 10

A comparison of PC oxidation products as detected by MALDI-TOF and ESI-IT mass spectrometry

Engel, K. M., & Schiller, J. (2017) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2016.12.007 · Cited by 10

Methods for Measurements of Oxidized LDL, Homocysteine and Nitric Oxide as Clinical Parameters of Oxidative Stress and Endothelial Dysfunction

Mačvanin, M., Stanimirović, J., & Isenović, E. R. (2022) · Current Analytical Chemistry · doi:10.2174/1573411018666220827142613 · Cited by 8

Separation of (Phospho)Lipids by Thin-Layer Chromatography

Fuchs, B., Popkova, Y., Süß, R., & Schiller, J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-417223-4.00014-5 · Cited by 8

A monoclonal antibody against oxidized lipoprotein recognizes foam cells in atherosclerotic lesions. Complex formation of oxidized phosphatidylcholines and polypeptides.

Itabe, H., Takeshima, E., Iwasaki, H., Kimura, J., Yoshida, Y., Imanaka, T., & Takano, T. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)36602-4 · Cited by 282

A New Anti-oxidized LDL Monoclonal Antibody that Recognizes Foam Cells

Itabe, H., Takeshima, E., Iwasaki, H., Kimura, J., Yoshida, Y., Imanaka, T., & Takano, T. (1994) · The Journal of Japan Atherosclerosis Society · doi:10.5551/jat1973.22.4_275 · Cited by 2

Monoclonal Antibodies Recognizing Atherosclerotic Lesions

Imanaka, T., Itabe, H., & Takano, T. (1996) · The Journal of Japan Atherosclerosis Society · doi:10.5551/jat1973.23.6_351

Oxidized phospholipids formed in oxidized LDL

Itabe, H. (2001) · The Journal of Japan Atherosclerosis Society · doi:10.5551/jat1973.28.3_63

Oxidized Low-density Lipoproteins: What Is Understood and What Remains to Be Clarified.

Itabe, H. (2003) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.26.1 · Cited by 148