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Regulated Co-translational Ubiquitination of Apolipoprotein B100
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When there is insufficient lipidation of nascent APOB in the ER, APOB undergoes ER-associated degradation (ERAD), which is mediated by the proteasome.
“When there is insufficient lipidation of nascent APOB in the ER, APOB undergoes ER-associated degradation (ERAD), which is mediated by the proteasome (21).”
From Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism (2012) · cites this paper as [21]
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Cited by
Sorted by citations
Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance
Choi, S. H., & Ginsberg, H. N. (2011) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2011.04.007 · Cited by 418
Self-citationChiang, K. P. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh216 · Cited by 278
Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism
Strong, A., Ding, Q., Edmondson, A. C., Millar, J. S., Sachs, K. V., Li, X., Kumaravel, A., Wang, M. Y., Ai, D., Guo, L., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci63563 · Cited by 222
Self-citationMeex, S. J. R., Andreo, U., Sparks, J. D., & Fisher, E. A. (2011) · Journal of Lipid Research · doi:10.1194/jlr.d008888 · Cited by 129
Self-citation
Metadata
- Authors
- Zhou, M., Fisher, E. A., & Ginsberg, H. N.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 1998-09
- Volume
- 273
- Issue
- 38
- Pages
- 24649-24653
- ISSN
- 0021-9258
- Cited by
- 139
- References
- 0
- Language
- en
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