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Cited by 411

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Adipose Tissue Resistin Expression Is Severely Suppressed in Obesity and Stimulated by Peroxisome Proliferator-activated Receptor γ Agonists

Open access
Way, James M., Görgün, Cem Z., Tong, Qiang, Uysal, K. Teoman, Brown, Kathleen K., Harrington, W. Wallace, Oliver, William R., Willson, Timothy M., Kliewer, Steven A., Hotamisligil, Gökhan S.·2001·Journal of Biological Chemistry
DOI 10.1074/jbc.c100189200
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Abstract

Elevated levels of the hormone resistin, which is secreted by fat cells, are proposed to cause insulin resistance and to serve as a link between obesity and type 2 diabetes. In this report we show that resistin expression is significantly decreased in the white adipose tissue of several different models of obesity including the ob/ob, db/db, tub/tub, and KKA(y) mice compared with their lean counterparts. Furthermore, in response to several different classes of antidiabetic peroxisome proliferator-activated receptor gamma agonists, adipose tissue resistin expression is increased in both ob/ob mice and Zucker diabetic fatty rats. These data demonstrate that experimental obesity in rodents is associated with severely defective resistin expression, and decreases in resistin expression are not required for the antidiabetic actions of peroxisome proliferator-activated receptor gamma agonists.

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Registry

Crossref · 10.1074/jbc.c100189200

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Metadata

Authors
Way, J. M., Görgün, C. Z., Tong, Q., Uysal, K. T., Brown, K. K., Harrington, W. W., Oliver, W. R., Willson, T. M., Kliewer, S. A., & Hotamisligil, G. S.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
2001-07
Volume
276
Issue
28
Pages
25651-25653
ISSN
0021-9258 (ISSN-L)
DOI
10.1074/jbc.c100189200
OpenAlex
W2051820078
Cited by
411
References
12
FWCI
40.17
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Adipose Tissue Resistin Expression Is Severely Suppressed in Obesity and Stimulated by Peroxisome Proliferator-activated Receptor γ Agonists. https://app.cochat.ai/papers/10.1074/jbc.c100189200
The paper
Way, J. M., Görgün, C. Z., Tong, Q., Uysal, K. T., Brown, K. K., Harrington, W. W., Oliver, W. R., Willson, T. M., Kliewer, S. A., & Hotamisligil, G. S. (2001). Adipose Tissue Resistin Expression Is Severely Suppressed in Obesity and Stimulated by Peroxisome Proliferator-activated Receptor γ Agonists. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.c100189200

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.