Structural Basis for Catalysis and Inhibition ofN-Glycan Processing Class I α1,2-Mannosidases

Cited by (156)

Items 101–156 of 156

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    Carine Chevrier, Albert Defoin, Céline Tarnus · 2007 · Bioorganic & Medicinal Chemistry
  2. Glycoprotein Folding in the Endoplasmic Reticulum
    Adam M. Benham, Ineke Braakman · 2000 · Critical Reviews in Biochemistry and Molecular Biology
  3. Use of Transient Transfection for cGMP Manufacturing of eOD-GT8 60mer, a Self-Assembling Nanoparticle Germline-Targeting HIV-1 Vaccine Candidate
    Vaneet Kumar Sharma, Sergey Menis, Evan T. Brower, Eddy Sayeed, Jim Ackland, Angela M. Lombardo, Christopher A. Cottrell, Jonathan L. Torres, Thomas Hassell, Andrew B. Ward et al. · 2024 · Pharmaceutics
  4. Serum alpha-mannosidase as an additional barrier to eliciting oligomannose-specific HIV-1-neutralizing antibodies
    Jean-François Bruxelle, Tess Kirilenko, Quratulain Qureshi, Naiomi Lu, Nino Trattnig, Paul Kosma, Ralph A. Pantophlet · 2020 · Scientific Reports
  5. Pharmacologic inhibition of N-linked glycan trimming with kifunensine disrupts GLUT1 trafficking and glucose uptake
    Evans K. Lodge, Jedediah D. Bell, Emily M. Roloff, Kathryn E. Hamilton, Larry L. Louters, Brendan D. Looyenga · 2020 · Biochimie
  6. Conformational Behaviour of Azasugars Based on Mannuronic Acid
    Erwin R. van Rijssel, Antonius P. A. Janssen, Alexandra Males, G.J. Davies, Gijsbert A. van der Marel, Herman S. Overkleeft, Jeroen D. C. Codée · 2017 · ChemBioChem
  7. Bacteroides thetaiotaomicron generates diverse α-mannosidase activities through subtle evolution of a distal substrate-binding motif
    Andrew J. Thompson, Richard J. Spears, Yanping Zhu, Michael D. L. Suits, Spencer John Williams, Harry John Gilbert, G.J. Davies · 2018 · Acta Crystallographica Section D Structural Biology
  8. Alkaloid Glycosidase Inhibitors
    Alan D. Elbein, Russell J. Molyneux · 2010 · Elsevier eBooks
  9. Evolving spike-protein N -glycosylation in SARS-CoV-2 variants
    Sabyasachi Baboo, Jolene K. Diedrich, Jonathan L. Torres, Jeffrey Copps, Bhavya Singh, Patrick T. Garrett, Andrew B. Ward, James C. Paulson, John R. Yates · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  10. Conformational analysis of seven-membered 1-N-iminosugars by NMR and molecular modelling
    Javier Pérez‐Castells, Marco Maria Fontanella, Ana Ardá, Francisco Javier Cañada, Matthieu Sollogoub, Yves Blériot, Jesús Jiménez‐Barbero · 2012 · New Journal of Chemistry
  11. Hematoxylin binds to mutant calreticulin and disrupts its abnormal interaction with thrombopoietin receptor
    Ruochen Jia, Thomas Balligand, Vasyl Atamanyuk, Harini Nivarthi, Erica Xu, Leon Kutzner, Jakob Weinzierl, Audrey Nédélec, Stefan Kubicek, Roman Lesyk et al. · 2020 · Blood
  12. The Reaction Coordinate of a Bacterial GH47 α‐Mannosidase: A Combined Quantum Mechanical and Structural Approach
    Andrew J. Thompson, Jérôme Dabin, Javier Iglesias‐Fernández, Albert Ardèvol, Zoran Dinev, Spencer John Williams, Omprakash P. Bande, Aloysius H. Siriwardena, Carl Moreland, Ting‐Chou Hu et al. · 2012 · Angewandte Chemie
  13. Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases
    Asha R. Johal, Brock Schuman, Javier A. Alfaro, Svetlana N. Borisova, Nina O.L. Seto, Stephen V. Evans · 2012 · Acta Crystallographica Section D Biological Crystallography
  14. GH47 and Other Glycoside Hydrolases Catalyze Glycosidic Bond Cleavage with the Assistance of Substrate Super-Arming at the Transition State
    Jonathan C.K. Quirke, David Crich · 2021 · ACS Catalysis
  15. The fate of β-d-mannopyranose after its formation by endoplasmic reticulum α-(1→2)-mannosidase I catalysis
    Chandrika Mulakala, Wim Nerinckx, Peter J. Reilly · 2006 · Carbohydrate Research
  16. Virtual screening and QSAR study of some pyrrolidine derivatives as α-mannosidase inhibitors for binding feature analysis
    N. S. Hari Narayana Moorthy, Natércia F. Brás, Maria João Ramos, Pedro Alexandrino Fernandes · 2012 · Bioorganic & Medicinal Chemistry
  17. Chemical Regulation of Glycosylation Processes
    Xue‐Long Sun · 2018 · Trends in Glycoscience and Glycotechnology
  18. Mitotic phosphorylation inhibits the Golgi mannosidase MAN1A1
    Shijiao Huang, Yoshimi Haga, Jie Li, Jianchao Zhang, Hye Kyong Kweon, Junichi Seino, Hiroto Hirayama, Morihisa Fujita, Kelley W. Moremen, Philip Andrews et al. · 2022 · Cell Reports
  19. Novel tools for the study of class I α-mannosidases: a chromogenic substrate and a substrate-analog inhibitor
    Tom Desmet, Wim Nerinckx, Ingeborg Stals, Nico Callewaert, Roland Contreras, Marc Claeyssens · 2002 · Analytical Biochemistry
  20. Processing of Protein-Bound N-Glycans
    Harry Schachter · 2007 · Elsevier eBooks
  21. Conversion of α1,2-mannosidase E-I from Candida albicans to α1,2-mannosidase E-II by limited proteolysis
    Hector Manuel Mora-Montes, Everardo López-Romero, Samuel Zinker, Patricia Ponce‐Noyola, Arturo Flores-Carreón · 2007 · Antonie van Leeuwenhoek
  22. Theory and computation show that Asp463 is the catalytic proton donor in human endoplasmic reticulum α-(1→2)-mannosidase I
    David C. Cantu, Wim Nerinckx, Peter J. Reilly · 2008 · Carbohydrate Research
  23. Middle East and Africa
    Carol Allais · 2006 · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
  24. Recombinant α-NAcetylgalactosaminidase from Marine Bacterium-Modifying A Erythrocyte Antigens
    Larissa Balabanova, Vasily Golotin, Irina Yu. Bakunina, Lubov Slepchenko, Vladimir V. Isakov, Анна Борисовна Подволоцкая, Valery A. Rasskazov · 2015 · Acta Naturae
  25. Modulation of activity by Arg407: structure of a fungal α-1,2-mannosidase in complex with a substrate analogue
    Yuri D. Lobsanov, Takashi Yoshida, Tom Desmet, Wim Nerinckx, Patrick Yip, Marc Claeyssens, Annette A. Herscovics, P. Lynne Howell · 2008 · Acta Crystallographica Section D Biological Crystallography
  26. Characterization of Solitalea canadensis α-mannosidase with specific activity towards α1,3-Mannosidic linkages
    Fangfang Liu, Meng Wang, Guan‐Hua Ma, Anna Kulinich, Li Liu, Josef Voglmeir · 2024 · Carbohydrate Research
  27. Expression, purification and preliminary crystallographic analysis ofDrosophila melanogasterlysosomal α-mannosidase
    Ivana Nemčovičová, Marek Nemčovič, Sergej Šesták, M. Plšková, Iain B. H. Wilson, J. Mucha · 2012 · Acta Crystallographica Section F Structural Biology and Crystallization Communications
  28. Mannosidase, Alpha, Class 1 (MAN1A1 (Golgi Alpha-Mannnosidase IA), Man1A2 (Golgi Alpha-Mannosidase IB), MAN1B1(ER Alpha-Mannosidase I), MAN1C1 (Golgi Alpha-Mannosidase IC))
    Kelley W. Moremen, Alison V. Nairn · 2014 · Springer eBooks
  29. Glycoproteins: Roles in Cellular Homeostasis and Disease
    Michael W. King · 2006 · Encyclopedia of Molecular Cell Biology and Molecular Medicine
  30. Improved expression and characterization of recombinant human Golgi α1,2-mannosidase I isoforms (IA2 and IC) by Escherichia coli
    Junko Isoyama-Tanaka, Koji Dohi, Ryo Misaki, Kazuhito Fujiyama · 2011 · Journal of Bioscience and Bioengineering
  31. Design and synthesis of iso- allo -DNJ and l -isoDALDP derivatives: pursuit of potent and selective inhibitors of α-glucosidase
    Linfeng Yang, Min Zhang, Yuna Shimadate, Atsushi Kato, Tian‐Yang Liu Hou, Yi‐Xian Li, Yue‐Mei Jia, George W. J. Fleet, Chu‐Yi Yu · 2023 · Organic & Biomolecular Chemistry
  32. Characterization of an extracellularly derived α-mannosidase from the liquid exudate of the sclerotia of Sclerotinia sclerotiorum (Lib.) de Bary
    Zhengli Liu, Ran Wei, Wen He, Ying Ruan, Chunlin Liu · 2015 · Antonie van Leeuwenhoek
  33. A new view of missense mutations in α ‐mannosidosis using molecular dynamics conformational ensembles
    Špela Mandl, Bruno Di Geronimo, Santiago Alonso‐Gil, Christoph Grininger, Gibu George, Ulrika Ferstl, Sereina Annik Herzog, Bojan Žagrović, Christoph Nusshold, Tea Pavkov‐Keller et al. · 2025 · Protein Science
  34. Shaping the Glycan Landscape: Hidden Relationships between Linkage and Ring Distortions Induced by Carbohydrate-Active Enzymes
    Isabell Louise Grothaus, Paul Spellerberg, Carme Rovira, Lucio Colombi Ciacchi · 2025 · Journal of the American Chemical Society
  35. Enzymes Involved in Generation and Degradation of the Free Oligosaccharides in the Cytosol of Caenorhabditis elegans
    Hisashi Ashida, Toshihiko Kato, Akihito Kawahara, Yuki Tanaka, Midori Umekawa, Kenji Yamamoto · 2009 · Journal of Applied Glycoscience
  36. Asparagine-Linked Glycosylational Modifications in Yeast
    Jyh-Ming Wu, Cheng‐Kang Lee, Tsu‐An Hsu · 2006 · Kluwer Academic Publishers eBooks
  37. FAM134B regulates ER-to-lysosome-associated degradation of misfolded proteins upon pharmacologic or genetic inactivation of ER-associated degradation
    Elisa Fasana, Ilaria Fregno, Carmela Galli, Maurizio Molinari · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  38. A ‘chiron’ approach to divergent synthesis of 2-C-tridecyl 1-N-iminosugar mimetics and their anticancer profile
    Monika Tvrdoňová, Peter Michalčin, Tatiana Pončáková, Yuliia Zuzak, Martina Bago Pilátová, Juraj Kuchár, Miroslava Litecká, Miroslava Martinková · 2025 · Carbohydrate Research
  39. Substrate Distortion by a Lichenase Highlights the Different Conformational Itineraries Harnessed by Related Glycoside Hydrolases
    V.A. Money, Nicola L. Smith, Adrian Scaffidi, Robert V. Stick, Harry John Gilbert, G.J. Davies · 2006 · Angewandte Chemie
  40. Structure and substrate specificity of GH47 alpha 1,2-mannosidases
    Yong Xiang · 2015
  41. Some Pathways of Carbohydrate Metabolism
    David E. Metzler, Carol M. Metzler, David J. Sauke · 2001 · Elsevier eBooks
  42. N-Linked Glycan Processing Glucosidases and Mannosidases
    Linda O. Tremblay, Annette A. Herscovics · 2004 · Encyclopedia of Biological Chemistry
  43. [Review: Symposium on Amylases and Related Enzymes] Catalytic Structure of GH47 α-Mannosidase
    Takashi Yoshida, Yohta Tatara, Yuri D. Lobsanov, Lynne Howell · 2011 · Bulletin of Applied Glycoscience
  44. Lysosomal storage disease: Disorders related to glycans and sialic acid
    Shyamasree Ghosh · 2020 · Elsevier eBooks
  45. Identification of New Metabolic Mutations in the Fission Yeast Schizosaccharomyces pombe that Sensitize the Cell to Hydroxyurea
    Alaa Taha A. Mahdi · 2020 · Journal of Bioresource Management
  46. Carbohydrate processing: an indispensable platform of pneumococcal virulence
    Edward P W Meier · 2021 · UVic’s Research and Learning Repository (University of Victoria)
  47. N-glycan Dependent Protein Quality Control System in the Endoplasmic Reticulum
    Satoshi Ninagawa · 2021 · Trends in Glycoscience and Glycotechnology
  48. N-glycan Dependent Protein Quality Control System in the Endoplasmic Reticulum
    Satoshi Ninagawa · 2021 · Trends in Glycoscience and Glycotechnology
  49. Enzymic Glycoside Hydrolysis and Transglycosylation: Kinetics and Mechanism
    2013 · Royal Society of Chemistry eBooks
  50. C-terminal domain mobility underpins substrate engagement by the Chaetomium thermophilum EDEM:PDI ERAD-L checkpoint complex
    Charlie J. Hitchman, Andrea Lia, Mohammed Bhogadia, Geander M. Pessoa, Gabriela N. Chirițoiu, Cristian V. A. Munteanu, Juan Ortigosa, Jorge Octavio Lannot, Simona Ghenea, Ikuo Wada et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  51. Conception et synthèse d’iminosucres multivalents bioactifs à motif glycoimidazole : développement d’une méthode de déshydroxylation sélective
    Maëva M. Pichon · 2018
  52. Biochemical characterization of the mannojirimycin biosynthetic enzymes reveals metal ion- and pH-dependent catalysis in Bacillus atrophaeus MBLB1156 isolated from red fermented bean curd (Hong fu ru)
    Hyo Jung Lim, Jeonghye Chun, Suhyeon Baek, Sanggil Lee, Jong‐Hyun Jung, Myung‐Ji Seo · 2026 · International Journal of Biological Macromolecules
  53. BindingDB Entry 50040964: Virtual screening and QSAR study of some pyrrolidine derivatives asa-mannosidase inhibitors for binding feature analysis.
    BindingDB · 2013 · UC San Diego
  54. BindingDB Entry 50004421: Mechanistic insights into a Ca2+-dependent family of alpha-mannosidases in a human gut symbiont.
    BindingDB · 2020 · UC San Diego
  55. BindingDB Entry 50037558: Biological properties of D- and L-1-deoxyazasugars.
    BindingDB · 2012 · UC San Diego
  56. BindingDB Entry 50037948: Synthesis and evaluation of amino-threoses in D- and L-series: are five membered ring amino-sugars more potent glycosidase inhibitors than the six membered ones?
    BindingDB · 2012 · UC San Diego