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Cited by 78

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Asialoglycoprotein Receptor Deficiency in Mice Lacking the Major Receptor Subunit

Tozawa, Ryu-ichi, Ishibashi, Shun, Osuga, Jun-ichi, Yamamoto, Kazuo, Yagyu, Hiroaki, Ohashi, Ken, Tamura, Yoshiaki, Yahagi, Naoya, Iizuka, Yoko, Okazaki, Hiroaki, Harada, Kenji, Gotoda, Takanari, Shimano, Hitoshi, Kimura, Satoshi, Nagai, Ryozo, Yamada, Nobuhiro·2001·Journal of Biological Chemistry
DOI 10.1074/jbc.m011063200
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Crossref · 10.1074/jbc.m011063200

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  • Previously established Asgr1-knockout mice by replacing exons 2-3 were unable to clear asialofetuin and asialo-orosomucoid.

    “Previously, Asgr1-knockout mice were established by replacing exons 2–3, which contain the ATG translational initiation codon and transmembrane domain (27). These ASGR1-knockout mice were unable to clear asialofetuin and asialo-orosomucoid.”

    From Hypomorphic ASGR1 modulates lipid homeostasis via INSIG1-mediated SREBP signaling suppression (2021) · cites this paper as [27]

    The Experimental Procedures describe replacing the fragment containing exons 2–3 to generate MHL-1 knockout mice. The Results report severely impaired clearance of both asialofetuin and asialo-orosomucoid, but not an inability to clear them: at 30 minutes, 40% and 65% of the respective doses remained in knockout mice. (LLM, conf=0.91)

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  • In previously established Asgr1-knockout mice, measurements of LDL and VLDL revealed a decreased trend with large standard deviations without a statistical difference, and serum TC and TG contents had no significant difference.

    “However, the measurements of LDL and VLDL revealed a decreased trend with large standard deviations without a statistical difference, and the serum TC and TG contents also had no significant difference.”

    From Hypomorphic ASGR1 modulates lipid homeostasis via INSIG1-mediated SREBP signaling suppression (2021) · cites this paper as [27]

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Research works printed but not linked: 33

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Metadata

Authors
Tozawa, R.-I., Ishibashi, S., Osuga, J.-I., Yamamoto, K., Yagyu, H., Ohashi, K., Tamura, Y., Yahagi, N., Iizuka, Y., Okazaki, H., Harada, K., Gotoda, T., Shimano, H., Kimura, S., Nagai, R., & Yamada, N.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
2001-04
Volume
276
Issue
16
Pages
12624-12628
ISSN
0021-9258
DOI
10.1074/jbc.m011063200
Cited by
78
References
1
Language
en
Licence

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