Reciprocal Phosphorylation and Regulation of Endothelial Nitric-oxide Synthase in Response to Bradykinin Stimulation

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Liu, J., Farmer, J. D., Lane, W. S., Friedman, J., Weissman, I., & Schreiber, S. L. (1991) · Cell · doi:10.1016/0092-8674(91)90124-h · Cited by 4,116

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

Dimmeler, S., Fleming, I., Fisslthaler, B., Hermann, C., Busse, R., & Zeiher, A. M. (1999) · Nature · doi:10.1038/21224 · Cited by 3,591

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Vlahos, C. J., Matter, W. F., Hui, K. Y., & Brown, R. F. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)37680-9 · Cited by 3,248

Nitric oxide: an endogenous modulator of leukocyte adhesion.

Kubes, P., Suzuki, M., & Granger, D. N. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.11.4651 · Cited by 3,036

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

Fulton, D. J., Gratton, J., McCabe, T. J. D., Fontana, J. T., Fujio, Y., Walsh, K. X., Franke, T. F., Papapetropoulos, A., & Sessa, W. C. (1999) · Nature · doi:10.1038/21218 · Cited by 2,616

Okadaic acid: a new probe for the study of cellular regulation

Cohen, P., Holmes, C. F. B., & Tsukitani, Y. (1990) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(90)90192-e · Cited by 1,373

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells.

Papapetropoulos, A., García‐Cardeña, G., Madri, J. A., & Sessa, W. C. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119868 · Cited by 1,195

The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

Radomski, M. W., Palmer, R. M. J., & Moncada, S. (1987) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1987.tb11367.x · Cited by 1,158

Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation

Coffer, P. J., Jin, J., & Woodgett, J. R. (1998) · Biochemical Journal · doi:10.1042/bj3350001 · Cited by 1,064

Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide.

Boulanger, C. M., & Lüscher, T. F. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114477 · Cited by 1,044

Inhibition of metastasis of syngeneic murine melanoma in vivo and vasculogenesis in vitro by monoclonal antibody C11C1 targeted to domain 5 of high molecular weight kininogen

Khan, S. T., Pixley, R. A., Liu, Y., Bakdash, N., Gordon, B. R. E., Agelan, A., Huang, Y., Achary, M. P., & Colman, R. W. (2010) · Cancer Immunology Immunotherapy · doi:10.1007/s00262-010-0915-0 · Cited by 7

Cellular mechanisms and intracellular signaling pathways for the modulation of eNOS in pulmonary arteries by 15-HETE

Yu, L., Liu, Y., Qiu, Z., Liu, S., Gao, X., & Zhu, D. (2012) · Journal of Receptors and Signal Transduction · doi:10.3109/10799893.2012.660530 · Cited by 7

Phosphorylation of myocardial eNOS is altered in patients suffering from type 2 diabetes

Streit, U., Reuter, H., Bloch, W., Wahlers, T., Schwinger, R. H. G., & Brixius, K. (2012) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00011.2011 · Cited by 7

Endothelial modulation of a nitric oxide donor complex-induced relaxation in normotensive and spontaneously hypertensive rats

Potje, S. R., Troiano, J. A., Grando, M. D., Graton, M. E., da Silva, R. S., Bendhack, L. M., & Antoniali, C. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.03.055 · Cited by 7

Effects of S-nitrosation of nitric oxide synthase

(2007) · Advances in experimental biology · doi:10.1016/s1872-2423(07)01007-1 · Cited by 7

Sodium orthovanadate induced tyrosine phosphorylation of platelet nitric oxide synthase negatively regulates enzyme activity

Milward, A. D., Riba, R., Patel, B., Oberprieler, N. G., & Naseem, K. M. (2006) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2006.06.004 · Cited by 7

Molecular Cloning of Ovine Endothelial Nitric Oxide Synthase and Expression in COS-7 Cells

Cale, J. M., Tsoi, S. C. ‐., Toppe, M., Grummer, M. A., Ochiai, M., Magness, R. R., & Bird, I. M. (2005) · Journal of the Society for Gynecologic Investigation · doi:10.1016/j.jsgi.2004.11.006 · Cited by 7

Telmisartan-induced eNOS gene expression is partially independent of its PPAR-gamma agonist property

Buset-Ríos, N., Rodríguez‐Esparragón, F., & Pérez, J. C. R. (2012) · Clinical and investigative medicine · doi:10.25011/cim.v35i2.16289 · Cited by 6

Interactive effects of in vitro binge-like alcohol and ATP on umbilical endothelial nitric oxide synthase post-translational modifications and redox modulation

Subramanian, K., Naik, V. D., Sathishkumar, K., Sawant, O. B., Washburn, S. E., Wu, G., Yallampalli, C., Saade, G. R., Hankins, G. D. V., & Ramadoss, J. (2013) · Reproductive Toxicology · doi:10.1016/j.reprotox.2013.11.006 · Cited by 6

Shear Stress and RBC-NOS Serine1177 Phosphorylation in Humans: A Dose Response

Horobin, J. T., Sabapathy, S., Kuck, L., & Simmonds, M. J. (2021) · Life · doi:10.3390/life11010036 · Cited by 6

Erythropoietin attenuates hypertrophy of neonatal rat cardiac myocytes induced by angiotensin‐IIin vitro

Wen, Y., Zhang, X., Ma, Y., Xu, X., Hong, L.-F., & Lu, Z. (2009) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365510902802286 · Cited by 6

Enhancing amplification of late‐outgrowth endothelial cells by bilobalide

Liu, S., Hou, X., Chen, L., Hu, H., Sun, Q., Zhao, F. H., & Liu, C. (2018) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13609 · Cited by 6

Omeprazole suppresses endothelial calcium response and eNOS Ser1177 phosphorylation in porcine aortic endothelial cells

Kamiya, C., Odagiri, K., Hakamata, A., Sakurada, R., Inui, N., & Watanabe, H. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06561-0 · Cited by 6

Hypertension, cancer and angiogenesis: Relevant Hypertension, cancer and angiogenesis: Relevant Hypertension, cancer and angiogenesis: Relevant Hypertension, cancer and angiogenesis: Relevant Hypertension, cancer and angiogenesis: Relevant epidemiological and pharmacological aspects epidemiological and pharmacological aspects epidemiological and pharmacological aspects epidemiological and pharmacological aspects epidemiological and pharmacological aspects

Ray, A., Ray, S., & Koner, B. C. (2004) · TSpace (University of Toronto) · Cited by 6

The Basal Phosphorylation Sites of Endothelial Nitric Oxide Synthase at Serine (Ser)1177, Ser116, and Threonine (Thr)495 in Rat Molar Epithelial Rests of Malassez

Korkmaz, Y., Bloch, W., Addicks, K., Schneider, K., Baumann, M. A., & Raab, W. H.-M. (2005) · Journal of Periodontology · doi:10.1902/jop.2005.76.9.1513 · Cited by 6

Biology of Nitric Oxide Synthases

Fleming, I. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-374530-9.00003-6 · Cited by 6

Investigation of the structure and dynamic of calmodulin-nitric oxide synthase complexes using NMR spectroscopy

Guillemette, J. G. (2018) · Frontiers in bioscience · doi:10.2741/4680 · Cited by 5

The developmental stage and cell type dependent phosphorylation of eNOS in murine enteric mucosa and myenteric plexus

Korkmaz, H., Bloch, W., Bölck, B., Labbé, D., Addicks, K., & Arnhold, S. (2007) · Journal of Molecular Histology · doi:10.1007/s10735-007-9091-8 · Cited by 5

Mechanisms of acupuncture and herbal medicine in hypertension

Kim, D. D., Sánchez, F. A., Borić, M. P., & Durán, W. N. (2008) · Americanae (AECID Library) · Cited by 5

Angiotensin Type 2 Receptor-Dependent Vasodilation

Yayama, K., & OKAMOTO, H. (2007) · YAKUGAKU ZASSHI · doi:10.1248/yakushi.127.1357 · Cited by 5

Endothelial nitric oxide synthase regulation is altered in pancreas from cirrhotic rats

Frossard, J., Quadri, R. A., Hadengue, A., Morel, P., & Pastor, C. M. (2006) · World Journal of Gastroenterology · doi:10.3748/wjg.v12.i2.228 · Cited by 4

Electrical stimulation of the carotid sinus lowers arterial pressure and improves heart rate variability in l-NAME hypertensive conscious rats

Domingos-Souza, G., Santos‐Almeida, F. M., Meschiari, C. A., Ferreira, N. S., Pereira, C. A., Martínez, D., Dias, D. P. M., Silva, L. E. V., Castania, J. A., Tostes, R. C., et al. (2020) · Hypertension Research · doi:10.1038/s41440-020-0448-7 · Cited by 4

Molecular mechanisms of exercise-induced cardiac rehabilitation

Ren, H., Jiang, C., Luo, Y., Liang, F., Nie, Z., Zhuo, P., Ke, X., & Wen, Y. (2026) · Life Sciences · doi:10.1016/j.lfs.2026.124476 · Cited by 5

Calcium-Dependent Interaction of Nitric Oxide Synthase with Cytochrome c Oxidase: Implications for Brain Bioenergetics

Haynes, V. L., & Giulivi, C. (2023) · Brain Sciences · doi:10.3390/brainsci13111534 · Cited by 3

Acanthopanax divaricatus var. chiisanensis reduces blood pressure via the endothelial nitric oxide synthase pathway in the spontaneously hypertensive rat model

Park, S.-Y., Do, G.-M., Lee, S., Lim, Y., Shin, J.-H., & Kwon, O. (2014) · Nutrition Research · doi:10.1016/j.nutres.2014.08.013 · Cited by 3

Attenuation of nitric oxide bioavailability in porcine aortic endothelial cells by classical swine fever virus

Wang, C.-Y. J., Yeh, H., Chang, T., Hsiao, H.-J., Tsai, M.-S., Tsai, S.-M., & Liu, P.-A. (2011) · Archives of Virology · doi:10.1007/s00705-011-0972-5 · Cited by 3

Nitric oxide synthase 3

Michel, T. M. (2009) · AfCS-Nature Molecule Pages · doi:10.1038/mp.a001660.01 · Cited by 3

NO Signaling Defects in Hypertension

Fleming, I. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804273-1.00023-5 · Cited by 3

Keratin-1 is a novel binding protein for C-reactive protein on the membrane of endothelial cells

Chu, Y., & Huang, K. (2015) · Journal of the Taiwan Institute of Chemical Engineers · doi:10.1016/j.jtice.2015.04.019 · Cited by 3

The Ca2+/calmodulin kinase/AMP-activated protein kinase pathway regulates the lectin phaseolus vulgaris agglutinin induced NO production in human platelets

Signorello, M. G., & Leoncini, G. (2019) · Integrative Molecular Medicine · doi:10.15761/imm.1000369 · Cited by 3

Protein phosphatase 4 mediates palmitic acid-induced endothelial dysfunction by decreasing eNOS phosphorylation at serine 633 in HUVECs

Liang, Z., Sun, G., Zhang, J., Zhang, Q., Li, X., Qin, S., Lv, S., Ding, J., Zhang, Q., Xia, Y., et al. (2024) · Experimental Cell Research · doi:10.1016/j.yexcr.2024.113998 · Cited by 3

Harboring of NOS to the Cell Membrane

Rőszer, T. (2012) · Springer eBooks · doi:10.1007/978-94-007-2819-6_6 · Cited by 2

Post-translational regulation of eNOS activity in inflammation

Desjardins, F., & Gratton, J. (2010) · Springer eBooks · doi:10.1007/978-3-0346-0168-9_4 · Cited by 1

Nitric Oxide in Human Physiology

Mohammed, M. K., & Zuckerbraun, B. S. (2022) · Wiley eBooks · doi:10.1002/9781119783435.ch8 · Cited by 1

The role of aryl hydrocarbon receptor in blood pressure regulation and vascular homeostasis

Zhang, N. (2009) · UNM’s Digital Repository (University of New Mexico)

Regulation of Kinin Receptor Expression in Heart Failure with a Focus on Vascular Endothelium

Liesmaa, I. (2010) · Työväentutkimus Vuosikirja

Down Syndrome and Vascular Disease: DSCR1 and NFAT Signaling

Monica, Y., & Brian, R. (2011) · InTech eBooks · doi:10.5772/22449

Cardioprotective mechanisms by inhibition of the HMG-CoA reductase pathway and stimulation of peroxisome proliferator-activated receptors in myocardial ischaemia-reperfusion

Bulhak, A. (2007) · Figshare

PMCA as a regulator of calcium/calmodulin-dependent signal transduction pathways

Holton, M. (2009) · Wolverhampton Intellectual Repository and E-Theses (University of Wolverhampton)

The Role of Argininosuccinate Synthase Serine 328 Phosphorylation in Nitric Oxide Production

Thompson, R. J. (2012) · Digital Commons - University of South Florida (University of South Florida)

Reatividade vascular e atividade da ECA em resposta ao treinamento físico são moduladas pelo polimorfismo +9/-9 do gene do receptor B2 de bradicinina

Alves, C. R. (2009) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.5.2009.tde-03022010-142937

revisão Bases Moleculares da Glomerulopatia Diabética

Lagranha, C. J., Fiorino, P., Casarini, D. E., & Irigoyen, M. C. (2007)

Genetic Disruption of Nitric Oxide Synthases and Cardiovascular Disease: Lessons from a Candidate Gene

Huang, P. L. (2004) · Handbook of experimental pharmacology · doi:10.1007/978-3-662-06214-2_11

Evaluation of pharmacological properties of Danshen compounds by computational and biochemical approaches

Zhou, Z. (2016) · RMIT Research Repository (RMIT University Library) · doi:10.25439/rmt.27581778

Kinins and kinin receptors in the pathogenesis of heart failure

Kuoppala, A. (2002) · Työväentutkimus Vuosikirja

The Reciprocal Regulation of Nitric Oxide Synthase and Alpha-subunit of Eukaryotic Initiation Factor 2 Post Ultraviolet B Irradiation

Lü, W. (2010) · OhioLink ETD Center (Ohio Library and Information Network)

Influence of Race, Gender, Age and Diabetes on Blood Flow

PETROFSKY, J. S. (2015) · Springer eBooks · doi:10.1007/978-3-642-27814-3_61-2

Effects of aging and exercise training on eNOS uncoupling and reactive oxygen species signaling in the endothelium of skeletal muscle arterioles

Sindler, A. L. (2009) · doi:10.33915/etd.2847

Hypertension, cancer and angiogenesis: Relevant Hypertension, cancer and angiogenesis: Relevant Hypertension, cancer and angiogenesis: Relevant Hypertension, cancer and angiogenesis: Relevant Hypertension, cancer and angiogenesis: Relevant epidemiological and pharmacological aspects epidemiological and pharmacological aspects epidemiological and pharmacological aspects epidemiological and pharmacological aspects epidemiological and pharmacological aspects

Ray, A., Ray, S., & Koner, B. C. (2004)

Hemodynamic Regulation of Endothelial Cell Gene Expression: Effects of p65 Expression Level on Constitutive and TNFα Induced NF-κB Signalling

Won, D. (2009) · TSpace (University of Toronto)

Acute Regulation of Vascular Tone by AMP-activated Protein Kinase in Arteries of Healthy, Hypertensive and Aged Rats

Ford, R. J. (2011) · UWSpace (University of Waterloo)

Nitric Oxide

Schini‐Kerth, V. B., & Vanhoutte, P. M. (2008) · doi:10.1002/9783527626236.ch16

A case of acute respiratory distress syndrome responsive to methylene blue during a carcinoid crisis Un cas de syndrome de detresse respiratoire aiguerepondant au bleu de methylene pendant une crise carcinoõ ¨de

van Diepen, S., Singh, G., & Mullen, J. C. (2013)

Nitric Oxide in Cardiovascular Biology and Pathophysiology

Corson, M. A. (2007) · Humana Press eBooks · doi:10.1007/978-1-59259-878-6_23

Influence of Race, Gender, Age, and Diabetes on Blood Flow

PETROFSKY, J. S. (2016) · Springer eBooks · doi:10.1007/978-3-662-47398-6_61

17 Kallikrein-kinin system in diabetes

Kakoki, M., & Smithies, O. (2011) · De Gruyter eBooks · doi:10.1515/9783110252354.273

表氧化二十碳三烯对eNOS磷酸化水平的影响

要是通过调节血管张力和血压, 抑., 蒋建刚, 肖啸, & 汪道文 (2005) · Science in China Series C-Life Sciences (in Chinese) · doi:10.1360/052004-36

Einfluss epigenetischer Modifikationen auf die Regulation des Gefäßtonus

Janetzko, P. (2022) · Publication Server of Goethe University Frankfurt am Main (Goethe University Frankfurt) · doi:10.21248/gups.67959

PI3K Isoforms in Vascular Biology, A Focus on the Vascular System-Immune Response Connection

Carnevale, D., Lembo, G., & Perrotta, S. (2022) · Current topics in microbiology and immunology · doi:10.1007/978-3-031-06566-8_12

Biology of Nitric Oxide Synthases

Fleming, I. (1984) · Comprehensive physiology · doi:10.1002/j.2040-4603.1984.tb01012.x

Redox regulation of protein serine/threonine phosphatase calcineurin

Namgaladze, D. (2002) · KOPS (University of Konstanz)

Fonctions catalytique et non-catalytique de la PI3Ky dans la réponse artérielle aux stress

Lupieri, A. (2017) · theses.fr (ABES) · doi:10.70675/61332ef3z8a76z49cbz83ecze3e6bfe1d31b

Biodisponibilidade cardiovascular do oxdo nitrico em camundongos LDLr-/-

Wanschel, A. C. B. A. (2010) · doi:10.47749/t/unicamp.2010.480714

Identification of Regulatory Sites of Phosphorylation of the Bovine Endothelial Nitric-oxide Synthase at Serine 617 and Serine 635

Michell, B. J., Harris, M. B., Chen, Z.-P., Ju, H., Venema, V. J., Blackstone, M. A., Huang, W., Venema, R. C., & Kemp, B. E. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205144200 · Cited by 212

Phosphorylation of Thr(495) regulates Ca(21)/calmodulin-dependent endothelial nitric oxide synthase activity. Circ Res 2001; 88:E68–E75

Fleming, I., Fißlthaler, B., Dimmeler, S., Kemp, B. E., & Busse, R. (2016)

Phosphorylation of Thr 495 Regulates Ca 2+ /Calmodulin-Dependent Endothelial Nitric Oxide Synthase Activity

Fleming, I., Fisslthaler, B., Dimmeler, S., Kemp, B. E., & Busse, R. (2001) · Circulation Research · doi:10.1161/hh1101.092677 · Cited by 770

Rapid increase in endothelial nitric oxide production by bradykinin is mediated by protein kinase A signaling pathway

Bae, S. W., Kim, H. S., Nam, Y., Park, Y. S., Jo, S. A., & Jo, I. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)01086-6 · Cited by 106

Bradykinin-regulated Interactions of the Mitogen-activated Protein Kinase Pathway with the Endothelial Nitric-oxide Synthase

Bernier, S. G., Haldar, S. M., & Michel, T. M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m005116200 · Cited by 190