Large Scale Gene Expression Analysis of Osteoclastogenesisin Vitro and Elucidation of NFAT2 as a Key Regulator

Ishida, Norihiro, Hayashi, Koji, Hoshijima, Mitsuhiro, Ogawa, Takuya, Koga, Shintaro, Miyatake, Yuuki, Kumegawa, Masayoshi, Kimura, Toru, Takeya, Tatsuo·2002·Journal of Biological Chemistry

Cited by (380)

Items 301–380 of 380

  1. Immunolocalization of Tumor Necrosis Factor Receptor–Associated Factor 6 in Rat Periapical Lesions
    Lijie Yang, Chi Zhang, Bin Peng · 2009 · Journal of Endodontics
  2. Overexpression of prohibitin-1 inhibits RANKL-induced activation of p38-Elk-1-SRE signaling axis blocking MKK6 activity
    Chang Hoon Lee, Sik‐Won Choi, Ju‐Young Kim, Seong Hwan Kim, Kwon‐Ha Yoon, Jaemin Oh, Myeung Su Lee · 2015 · Biochemical and Biophysical Research Communications
  3. A novel role of helix‐loop‐helix transcriptional factor Bhlhe40 in osteoclast activation
    Hirohito Hirata, Asana Kamohara, Masatoshi Murayama, Kenichi Nishioka, Hiroaki Honda, Yasuteru Urano, Hidenobu Soejima, Shinya Oki, Toshio Kukita, Shunsuke Kawano et al. · 2022 · Journal of Cellular Physiology
  4. Developmental Pathways in CAVD
    E. Elaine, Elsha Katherine · 2013 · InTech eBooks
  5. Cellular Trans-Differentiation and Morphogenesis Toward the Lymphatic Lineage in Regenerative Medicine
    Filip Laco, Mary Helen Grant, David J. Flint, R.A. Black · 2010 · Stem Cells and Development
  6. Osteoclasts
    Naoyuki Takahashi, Yasuhiro Kobayashi, Nobuyuki Udagawa · 2019 · Elsevier eBooks
  7. Cell-Based Assay Strategy for Identification of Motif-Specific RANK Signaling Pathway Inhibitors
    Taosheng Chen, Xu Feng · 2006 · Assay and Drug Development Technologies
  8. The Activating Protein-1 Transcriptional Complex: Essential and Multifaceted Roles in Bone
    Junro Yamashita, Laurie K. McCauley · 2006 · Clinical Reviews in Bone and Mineral Metabolism
  9. Overexpression of PIK3R1 Promotes Bone Formation by Regulating Osteoblast Differentiation and Osteoclast Formation
    Haitao Zhu, Hua Chen, Degang Ding, Shui Wang, Xiaofeng Dai, Yulong Zhu · 2021 · Computational and Mathematical Methods in Medicine · Retracted
  10. The G9a histone methyltransferase represses osteoclastogenesis and bone resorption by regulating NFATc1 function
    Koichiro Komatsu, Hisashi Ideno, Kazuhisa Nakashima, Nobuyuki Udagawa, Yasuhiro Kobayashi, Hiroshi Kimurâ, Makoto Tachibana, T. Yamashita, Akira Nifuji · 2024 · The FASEB Journal
  11. Contributions to osteoclast biology from Japan
    Tatsuo Suda, Naoyuki Takahashi · 2008 · Proceedings of the Japan Academy Series B
  12. The T-Cell Oncogene Tal2 Is a Target of PU.1 and Upregulated during Osteoclastogenesis
    Nadine Courtial, Christian Mücke, Stefanie C. Herkt, Stephan Kolodziej, Helge Hussong, Jörn Lausen · 2013 · PLoS ONE
  13. Identification and characterization of anti-osteoclastogenic peptides derived from the cytoplasmic tail of receptor activator of nuclear factor kappa B
    Yuu Taguchi, Yoko Kiga, Jin Gohda, Jun‐ichiro Inoue · 2012 · Journal of Bone and Mineral Metabolism
  14. Prostaglandin F2α negatively regulates bone resorption in murine osteoclast development
    Masayoshi Kamon, D. Fujita, Natsuka Goto, Hitoshi Amano, Kazuichi Sakamoto · 2008 · Prostaglandins & Other Lipid Mediators
  15. Effect of N-Vinyl-2-Pyrrolidone (NVP), a Bromodomain-Binding Small Chemical, on Osteoblast and Osteoclast Differentiation and Its Potential Application for Bone Regeneration
    Viviane A. Klemmer, Nupur Khera, Barbara M. Siegenthaler, Indranil Bhattacharya, Franz E. Weber, Chafik Ghayor · 2021 · International Journal of Molecular Sciences
  16. Retrovirus-mediated conditional immortalization and analysis of established cell lines of osteoclast precursor cells
    Shigehisa Kawata, Jun Suzuki, Masahiro Maruoka, Megumi Mizutamari, Norihiro Ishida‐Kitagawa, Keiichiro Yogo, Parmjit Jat, Tomoyuki Shishido · 2006 · Biochemical and Biophysical Research Communications
  17. The prevention of latanoprost on osteoclastgenesis in vitro and lipopolysaccharide‐induced murine calvaria osteolysis in vivo
    Xing Yue Xu, Yufei Yan, Zhuochao Liu, Qi Jin, Niandong Qian, Hanbing Zhou, Qi Zhou, Tianqi Wang, Ping Huang, Lei Guo et al. · 2017 · Journal of Cellular Biochemistry
  18. Siglec15 in blood system diseases: from bench to bedside
    Yujia Fan, Liangliang Sun, Juan He, Yuetong Chen, Hongli Ma, Haitao Ding · 2024 · Frontiers in Immunology
  19. Inhibition of Osteoclast Differentiation and Promotion of Osteogenic Formation by Wolfiporia extensa Mycelium
    Tae Hyun Son, Shin‐Hye Kim, Hye-Lim Shin, Dong‐Soo Kim, Jin-Sung Huh, Rhim Ryoo, Yongseok Choi, Sik‐Won Choi · 2023 · Journal of Microbiology and Biotechnology
  20. Role of nuclear factor of activated T cells in chondrogenesis osteogenesis and osteochondroma formation
    ERNESTO M. CANALIS, Lauren Schilling, Tabitha Eller, Jungeun Yu · 2022 · Journal of Endocrinological Investigation
  21. Monascin abrogates RANKL-mediated osteoclastogenesis in RAW264.7 cells via regulating MAPKs signaling pathways
    Yin Cheng, Haixia Liu, Jing Li, Yujie Ma, Changheng Song, Yuhan Wang, Pei Li, Yanjing Chen, Zhiguo Zhang · 2022 · Frontiers in Pharmacology
  22. Genetics and Mutations Affecting Osteoclast Development and Function
    Mark C. Horowitz, Melissa A. Kacena, Joseph Lorenzo · 2005 · Springer eBooks
  23. Aminocoumarins inhibit osteoclast differentiation and bone resorption via downregulation of nuclear factor of activated T cells c1
    Ting Zheng, A Long Sae Mi Noh, Hyojung Park, Mijung Yim · 2012 · Biochemical Pharmacology
  24. Genetic and Epigenetic Aspects of Bone Development
    Rose D. O’Connor, Mary C. Farach‐Carson, N. Carolyn Schanen · 2010 · Springer eBooks
  25. O-GlcNAcylation: Sagacious Orchestrator of Bone-, Joint-, and Spine-Related Diseases
    Guihuo Wei, Hao Jia, Zhuo Zhang, Jianpu Qin, Jun Ao, Qian Hu · 2025 · Journal of Proteome Research
  26. Protective protein/cathepsin A down-regulates osteoclastogenesis by associating with and degrading NF-κB p50/p65
    Masaaki Masuhara, Takuya Sato, Naoto Hada, Yoshiyuki Hakeda · 2008 · Journal of Bone and Mineral Metabolism
  27. Novel diether compounds inhibiting differentiation of osteoclasts
    Kyung‐Eun Doh, Ju‐Hee Kang, Ting Zheng, Mijung Yim, Hea‐Young Park Choo · 2015 · Archives of Pharmacal Research
  28. Purification and Biological Function of Caldecrin
    Akito Tomomura, Kenjiro Bandow, Mineko Tomomura · 2021 · Medicines
  29. Bovine collagen peptides and peptide–calcium complexes inhibit RANKL ‐induced osteoclast differentiation in RAW 264.7 macrophages
    Yuanyi Liu, Yue Zhu, Yixin Zhao, Jin Wang, Yiying Yu, Jin Zhu, Guofeng Jin · 2025 · Journal of the Science of Food and Agriculture
  30. Is There a Role for NFAT Inhibitors in the Prevention of Bone Destruction?
    Mark S. McMahon · 2009 · HSS Journal® The Musculoskeletal Journal of Hospital for Special Surgery
  31. Effects of gallotannin on osteoclastogenesis and the p38 MAP kinase pathway
    Yukiko Hosoyama, Eisuke Domae, Seiji Goda, Naoyuki Matsumoto · 2016 · Orthodontic Waves
  32. Osteoclast-rich lesions of bone: a clinical and molecular overview
    Adrienne Margaret Flanagan, Roberto Tirabosco, Panagiotis D. Gikas · 2014 · Elsevier eBooks
  33. Breast Cancer Metastases to Bone: Role of the Microenvironment
    E. Jenna, Валерьевна Светлана · 2011 · InTech eBooks
  34. (–)-Epigallocatechingallate Interferes RANKL/RANK Signal Pathway and Induces Apoptosis during Osteoclastogenesis in RAW264 Cell
    Ran Zhao, Masayoshi Kamon, Kazuichi Sakamoto · 2014 · Food and Nutrition Sciences
  35. Skimmianine Attenuates Osteoclast Activity by Suppressing ERp57‐ Driven Calcium Oscillations/Calcineurin/Nfatc1 Signalling in Postmenopausal Osteoporosis
    Yongshuang Lv, Xin Zhang, Qizhen Lu, Yi Zhou, Weiyi Wang, Maosheng Yang, Tao Yuan, Yikai Liu, Shui Sun, Ziqing Li · 2025 · Journal of Cellular and Molecular Medicine
  36. P2 Nucleotide Receptor Signaling in Osteoclasts
    Jasminka Korčok, S. Jeffrey Dixon, Stephen M. Sims · 2006 · CRC Press eBooks
  37. Enhanced BMP signaling via ALK2 in osteoclasts decreases bone density in mice
    Hiroyuki Yamaguchi, Yolanda V Gutierrez, Maryam Faisal, Yuta Nakai, Lauren T Tran, Baohong Zhao, Yuji M. Mishina, Yoshihiro Komatsu · 2025 · Biochemical and Biophysical Research Communications
  38. The l-Ser analog #290 promotes bone recovery in OP and RA mice
    Anton Bahtiar, Takashi Nakamura, Koichi Kishida, Junpei Katsura, Mai Nitta, Norihiro Ishida‐Kitagawa, Takuya Ogawa, Tatsuo Takeya · 2011 · Pharmacological Research
  39. Nuclear factor of activated T-cells 1 increases sensitivity of v-myb transformed monoblasts to all-trans retinoic acid
    Filip Trčka, Jan Šmarda, Lucia Knopfová, Kateřina Kuziaková, Petr Beneš · 2013 · Cellular Signalling
  40. TGF-β Negatively Regulates Mitf-E Expression and Canine Osteoclastogenesis
    Kumiko Asai, Masaharu Hisasue, Fumie Shimokawa, Masayuki Funaba, Masaru Murakami · 2018 · Biochemical Genetics
  41. Genomic Profiling in Bone
    Aimy Sebastian, Gabriela G. Loots · 2017 · Elsevier eBooks
  42. Regulation of transcriptional network system during bone and cartilage development
    Riko Nishimura, Kenji Hata, Fumiyo Ikeda, Takuma Matsubara, Katsuhiko Amano, Koichiro Ono, Yoko Takigawa, Rikako Takashima, Michiko Yoshida, Eriko Nakamura et al. · 2015 · Journal of Oral Biosciences
  43. An Emerging Role of Cathelicidin Antimicrobial Peptides in Bone Biology
    Suttichai Krisanaprakornkit · 2014
  44. Developmental Pathways and Aortic Valve Calcification
    M. Victoria Gomez‐Stallons, Keira R. Hassel, Katherine E. Yutzey · 2020 · Contemporary cardiology
  45. Applied Bioinformatics for Drug Discovery and Development
    Jian Chen, Shujian Wu, Daniel B. Davison · 2005 · Wiley eBooks
  46. RANK signaling pathways as potent and specific therapeutic targets for bone erosion in rheumatoid arthritis
    Xu Feng · 2006 · Future Rheumatology
  47. Meeting report from the 25th annual meeting of the American society for bone and mineral research
    Aubrey Blumsohn, Roberta Faccio, Yebin Jiang, Gérard Karsenty, Robert F. Klein, Mark A. Kotowicz, Ian R. Reid, Pamela Gehron Robey, Ego Seeman, Gordon J Strewler · 2003 · BoneKEy-Osteovision
  48. Osteoclast Signal Transduction Pathways: The RANKL/RANK System
    Zhenqiang Yao, Brendan F. Boyce · 2019 · Elsevier eBooks
  49. Osteoclast Gene Regulation
    Kevin P. McHugh · 2020 · Elsevier eBooks
  50. Receptor activator of nuclear factor кB ligand (RANKL) versus osteoprotegerin (OPG): the yin and yang of joint integrity
    Brad N. Bolon, Victoria Shalhoub, Paul J. Kostenuik, Debra Jeske Zack, Ulrich Feige · 2004 · Birkhäuser Basel eBooks
  51. Osteoclast-rich Lesions of Bone
    Adrienne Margaret Flanagan, Roberto Tirabosco, Panagiotis D. Gikas · 2010 · Elsevier eBooks
  52. The calcitonin gene family of peptides : receptor expression and effects on bone cells
    Susanne Granholm · 2008 · KTH Publication Database DiVA (KTH Royal Institute of Technology)
  53. Identification of Alternatively Spliced Forms of human OSCAR in Osteoclasts
    Nacksung Kim, Hong Yong Park, Hyun Dong Kim · 2012 · Korean Journal of Bone Metabolism
  54. Osteoclast Development and Function
    Mark C. Horowitz, Melissa A. Kacena, Joseph Lorenzo · 2005
  55. Adseverin is a Key Regulator and Marker of Osteoclastogenesis
    Siavash Hassanpour · 2010 · TSpace (University of Toronto)
  56. Regulation of osteoclast differentiation by transcription factors MITF, PU.1 and EOS.
    Rong Hu · 2007 · OhioLink ETD Center (Ohio Library and Information Network)
  57. Critical molecules in bone development and genetic bone diseases
    Qing Wang, Ming Zhang, Tianhui Zhu, Di Chen · 2007
  58. Receptor Activator of NF-κB (RANK) Signaling
    Hiroshi Takayanagi · 2008 · Elsevier eBooks
  59. Elucidating Differences in Osteoclast Activation Mechanisms: Looking for Targets to Prevent Pathological Bone Resorption
    Diana P. Trebec‐Reynolds · 2010 · TSpace (University of Toronto)
  60. Immunopathology of the Musculoskeletal System
    Brad N. Bolon, Jairo S. Nunes · 2017 · Molecular and integrative toxicology
  61. Study on Pulsed Electromagnetic Fields Regulate the mRNA Expression of V-ATPase, CAII, NFAT2 and RANK in an Ovariectomized Rat Model of Osteoporosis Mechanism Analysis
    Hui Huang, Jian Chen, Jian He, Ji Fu · 2017 · Journal of Bioengineering and Biomedical Sciences
  62. DIHYDROTESTOSTERONE DOWNREGULATES BONE RESORPTION ACTIVITY OF OSTEOCLASTS IN DOSE DEPENDENT MANNER: AN IN VITRO MODEL USING RAW 264.7 CELLS
    Hnin Ei Thu, Zahid Hussain, Isa Naina Mohamed, Ahmad Nazrun Shuid · 2017 · International Journal of Pharmacy and Pharmaceutical Sciences
  63. Genomic Profiling in Bone
    Bryan D. Hudson, Gabriela G. Loots · 2012 · Elsevier eBooks
  64. Antibody mediated “Universal” Osteoclast targeting platform
    Madhuri Newa · 2013 · ERA: Education and Research Archive (University of Alberta)
  65. Transcriptional Profiling for Genetic Assessment
    Aimy Sebastian, Gabriela G. Loots · 2018 · Primer on the metabolic bone diseases and disorders of mineral metabolism
  66. Clinical case of mandibular fibro-osseous lesions with giant multinuclear cells: molecular-genetic differential diagnostic analysis
    Е.Г. Свиридов, Roman V. Deev, N. Redko, Aleksey Yu. Drobyshev, A. I. Kadykova · 2019 · Genes and Cells
  67. Effects of pulsed electromagnetic fields on the expression of NFATc1 and CAII in mouse osteoclast-like cells
    Jianquan HeYongsheng, Chen Zhangjian, Suyu ZhengHui, HuangXiaoyu Dong · 2015
  68. RANKL Signaling Pathway: A Potential Target for Antiresorptive Therapy in Rheumatoid Arthritis
    Sidrah Anjum, Attya Bhatti, Fahd Qadir, Usman Ashraf, Peter C. L. John · 2021 · NUST Journal of Natural Sciences
  69. An Osler Commemorative Stamp.
    L Whitby · 1949 · Europe PMC (PubMed Central)
  70. Osteoclast-rich lesions of bone
    Adrienne Margaret Flanagan, Roberto Tirabosco, Fernanda M Amary · 2021 · Elsevier eBooks
  71. P2 Nucleotide Receptor Signaling in Osteoclasts
    Jasminka Korčok, S. Jeffrey Dixon, Stephen M. Sims · 2006 · CRC Press eBooks
  72. Investigação de marcadores moleculares sanguíneos durante a infecção pelo vírus Chikungunya
    Alysson H. Urbanski · 2023
  73. La fonction de résorption des ostéoclastes : mécanismes cellulaires et implication au cours du développement osseux
    Heiani Touaitahuata · 2012 · theses.fr (ABES)
  74. Étude de l'évolution du phénotype osseux et de l'activation de l'inflammasome dans un modèle murin du chérubisme
    B. Rabhi · 2024
  75. Sidt2 Knockdown Aggravates Apical Periodontitis Via Autocrine Tumour Necrosis Factor-Alpha
    Biao Li, Gengming Zhang, Min Quan Du, Hong He · 2026 · International Dental Journal
  76. Non-bone resorbing osteoclasts: Emerging roles in bone homeostasis, pathologies, and translational therapeutics
    Shuo Li, Huibo Ti, Jun-jie Wu, Zhenyu Zhang, Haiting Hu, Feng-lai Yuan, Jun-Xing Ye, Xia Li · 2026 · Materials Today Advances
  77. A NanoBiT-based high-throughput assay system for monitoring osteoclast fusion
    Muneaki Yoshino, Sumire Hanahira, Momoka Nakatani, Wataru Fujii, Norihiro Ishida‐Kitagawa, Takuya Ogawa, Keiichiro Yogo · 2026 · Analytical Biochemistry
  78. BindingDB Entry 50016378: Development of an Orally Active Small-Molecule Inhibitor of Receptor Activator of Nuclear Factor-κB Ligand.
    BindingDB · 2023 · UC San Diego
  79. BindingDB Entry 50046727: 5-Lipoxygenase inhibitors suppress RANKL-induced osteoclast formation via NFATc1 expression.
    BindingDB · 2016 · UC San Diego
  80. BindingDB Entry 50009071: Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-Receptor Activator of Nuclear Factor-κB (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization.
    BindingDB · 2021 · UC San Diego