Large Scale Gene Expression Analysis of Osteoclastogenesisin Vitro and Elucidation of NFAT2 as a Key Regulator

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Identification of a Novel l-Serine Analog That Suppresses Osteoclastogenesis in Vitro and Bone Turnover in Vivo

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Lectin-like oxidized low-density lipoprotein receptor-1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state

Nakayachi, M., Ito, J., Hayashida, C., Ohyama, Y., Kakino, A., Okayasu, M., Sato, T., Ogasawara, T., Kaneda, T., Suda, N., et al. (2015) · Bone · doi:10.1016/j.bone.2015.02.025 · Cited by 15

Protocatechualdehyde inhibits receptor activator of nuclear factor kappa‐B ligand ‐induced osteoclastogenesis and attenuates lipopolysaccharide‐induced inflammatory osteolysis

Huang, H., Jiang, W., Hong, K., Cai, J., He, Y., Ma, X., Wu, P., Lang, J., Ma, Y., Huang, C., et al. (2021) · Phytotherapy Research · doi:10.1002/ptr.7088 · Cited by 14

Nuclear factor of activated T cells 1 and 2 are required for vertebral homeostasis

CANALIS, E. M., Schilling, L., Eller, T., & Yu, J. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29696 · Cited by 15

PC‐PLC is involved in osteoclastogenesis induced by TNF‐α through upregulating IP3R1 expression

Xia, L., Zhang, D.-Y., Wang, C., Wei, F.-C., & Hu, Y.-W. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.07.015 · Cited by 13

L-type Ca2+ channel agonist inhibits RANKL-induced osteoclast formation via NFATc1 down-regulation

Noh, A. L. S. M., Park, H., Zheng, T., Ha, H., & Yim, M. (2011) · Life Sciences · doi:10.1016/j.lfs.2011.05.009 · Cited by 14

Dental Application of Natural Products

Sakagami, H., & Tomomura, M. (2018) · Medicines · doi:10.3390/medicines5010021 · Cited by 14

Eurycoma longifolia, a promising suppressor of RANKL-induced differentiation and activation of osteoclasts: An in vitro mechanistic evaluation

Thu, H. E., Hussain, Z., Mohamed, I. N., & Shuid, A. N. (2018) · Journal of Ayurveda and Integrative Medicine · doi:10.1016/j.jaim.2017.07.014 · Cited by 14

Effect of Kiwifruit on Bone Resorption in Ovariectomized Mice

Katsumata, S.-I., Wolber, F. M., Tadaishi, M., Tousen, Y., Ishimi, Y., & Kruger, M. C. (2015) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.61.332 · Cited by 14

Siglec-15 as multifunctional molecule involved in osteoclast differentiation, cancer immunity and microbial infection

Huang, R., Zheng, J., Shao, Y., Zhu, L., & Yang, T. (2022) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2022.10.006 · Cited by 13

Mechanical control of osteoclast fusion by membrane-cortex attachment and BAR proteins

Wan, Y., Nemoto, Y. L., Oikawa, T., Takano, K., Fujiwara, T. K., Tsujita, K., & Itoh, T. (2025) · The Journal of Cell Biology · doi:10.1083/jcb.202411024 · Cited by 13

Effects of Type 2 Diabetes Mellitus on Osteoclast Differentiation, Activity, and Cortical Bone Formation in POSTmenopausal MRONJ Patients

Park, S.-M., & Lee, J. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11092377 · Cited by 14

Osteoclast Apoptosis in Rheumatic Diseases Characterized by a High Level of Bone Resorption (Osteoporosis, Rheumatoid Arthritis, Myeloma and Pagets Disease of Bone)

Roux, S., & Brown, J. P. (2009) · Current Rheumatology Reviews · doi:10.2174/157339709788298428 · Cited by 12

Nuclear factor of activated T cells 2 is required for osteoclast differentiation and function in vitro but not in vivo

Yu, J., Zanotti, S., Schilling, L., & CANALIS, E. M. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.27212 · Cited by 11

SH3BP2 mutations potentiate osteoclastogenesis via PLCγ

Lietman, S. A., Yin, L., & Levine, M. A. (2010) · Journal of Orthopaedic Research® · doi:10.1002/jor.21164 · Cited by 11

9-Demethoxy-medicarpin promotes peak bone mass achievement and has bone conserving effect in ovariectomized mice: Positively regulates osteoblast functions and suppresses osteoclastogenesis

Goel, A., Raghuvanshi, A., Kumar, A., Gautam, A. K., Srivastava, K., Kureel, J., & Singh, D. R. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.04.023 · Cited by 11

Critical role of NFATc1 in periapical lesions

Zhang, C., Yang, L., & Peng, B. (2010) · International Endodontic Journal · doi:10.1111/j.1365-2591.2009.01649.x · Cited by 10

Adenovirus-Encoding Virus-Associated RNAs Suppress HDGF Gene Expression to Support Efficient Viral Replication

Kondo, S., Yoshida, K., Suzuki, M., Saito, I., & Kanegae, Y. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108627 · Cited by 10

CMT3 alters mitochondrial function in murine osteoclast lineage cells

Holmes, S., Smith, S., Borthwick, L. A., Dunford, J. E., Rogers, M., Bishop, N. J., & Grabowski, P. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.11.054 · Cited by 10

Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity

Peng, B., Li, Z., Cheng, Y., Jiang, H., Ye, Q., & Han, G. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04146-3 · Cited by 9

Yangonin treats inflammatory osteoporosis by inhibiting the secretion of inflammatory factors and RANKL expression

Lu, F., Wu, X., Hu, H., Zhang, J., Song, X., Jin, X., Chen, L., Sun, J., & Chen, H. (2022) · Inflammopharmacology · doi:10.1007/s10787-022-00985-1 · Cited by 9

Acid sphingomyelinase regulates osteoclastogenesis by modulating sphingosine kinases downstream of RANKL signaling

Bao, X., Ogawa, T., Se, S., Akiyama, M., Bahtiar, A., Takeya, T., & Ishida‐Kitagawa, N. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.01.061 · Cited by 9

Irreversible inhibition of RANK expression as a possible mechanism for IL-3 inhibition of RANKL-induced osteoclastogenesis

Khapli, S. M., Tomar, G. B., Barhanpurkar, A. P., Gupta, N., Yogesha, S. D., Pote, S. T., & Wani, M. R. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.07.143 · Cited by 9

Negative autoregulation of RANKL and c-Src signaling in osteoclasts

Yogo, K., Ishida‐Kitagawa, N., & Takeya, T. (2007) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-007-0751-2 · Cited by 8

Gene array identification of osteoclast genes: Differential inhibition of osteoclastogenesis by cyclosporin A and granulocyte macrophage colony stimulating factor

Day, C. J., Kim, M. S., Stephens, S., Simcock, W. E., Aitken, C. J., Nicholson, G. C., & Morrison, N. A. (2004) · Journal of Cellular Biochemistry · doi:10.1002/jcb.10780 · Cited by 52

RANK-L induces the expression of NFATc1, but not of NFκB subunits during osteoclast formation

Zhu, L., Zaidi, S., Moonga, B. S., Troen, B. R., & Sun, L. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.10.212 · Cited by 23

The Calcineurin/Nuclear Factor of Activated T Cells Signaling Pathway Regulates Osteoclastogenesis in RAW264.7 Cells

Hirotani, H., Tuohy, N. A., Woo, J.-T., Stern, P. H., & Clipstone, N. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m213067200 · Cited by 248

Receptor Activator of Nuclear Factor-κB Ligand-Induced Nuclear Factor of Activated T Cells (C1) Autoregulates Its Own Expression in Osteoclasts and Mediates the Up-Regulation of Tartrate-Resistant Acid Phosphatase

Fretz, J. A., Shevde, N. K., Singh, S., Darnay, B. G., & Pike, J. W. (2007) · Molecular Endocrinology · doi:10.1210/me.2007-0333 · Cited by 27

CCR1 Acts Downstream of NFAT2 in Osteoclastogenesis and Enhances Cell Migration

Ishida, N., Hayashi, K., Hattori, A., Yogo, K., Kimura, T., & Takeya, T. (2006) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.051001 · Cited by 41