Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke

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Items 101–200 of 334

1. Age-related changes in AMP-activated protein kinase after stroke
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2. Function of the master energy regulator adenosine monophosphate‐activated protein kinase in stroke
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3. AMP-activated protein kinase: Structure, function, and role in pathological processes
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4. Acute renal ischemia rapidly activates the energy sensor AMPK but does not increase phosphorylation of eNOS-Ser1177
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5. Blood–Brain Barrier Na Transporters in Ischemic Stroke
   Martha E. O’Donnell · 2014 · Advances in pharmacology
6. Differential mechanisms underlying neuroprotection of hydrogen sulfide donors against oxidative stress
   Jia Jia, Yunqi Xiao, Wei Wang, Lina Qing, Yinxiu Xu, Heng Song, Xuechu Zhen, Gui‐Zhen Ao, Nabil J. Alkayed, Jian Gong Cheng · 2013 · Neurochemistry International
7. Anthocyanins Protect against Kainic Acid‐induced Excitotoxicity and Apoptosis via ROS ‐activated AMPK Pathway in Hippocampal Neurons
   Ikram Ullah, Hyun Young Park, Myeong Ok Kim · 2014 · CNS Neuroscience & Therapeutics
8. Inhibiting ferroptosis: A novel approach for stroke therapeutics
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9. AMPK-mediated regulation of neuronal metabolism and function in brain diseases
   Yu‐Ju Liu, Yijuang Chern · 2015 · Journal of Neurogenetics
10. Bioenergy sensing in the brain
    Stephen Amato, Heng‐Ye Man · 2011 · Cell Cycle
11. Protective effects of AMP‐activated protein kinase in the cardiovascular system
    Qiang Xu, Liang‐Yi Si · 2010 · Journal of Cellular and Molecular Medicine
12. Differential regulation of AMP-activated kinase and AKT kinase in response to oxygen availability in crucian carp (Carassius carassius)
    Kåre‐Olav Stensløkken, Stian Ellefsen, Jonathan A. W. Stecyk, Mai Britt Dahl, Göran Nilsson, Jarle Vaage · 2008 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
13. AMPK activation regulates neuronal structure in developing hippocampal neurons
    Ramamurthy, S., Chang, E., Cao, Y., Zhu, J., Ronnett, G.V. · 2014 · Neuroscience
14. Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy
    Mushfiquddin Khan, Tajinder S. Dhammu, Fumiyo Matsuda, Avtar Kaur Singh, Inderjit Singh · 2015 · BMC Neuroscience
15. Neuroprotection targeting ischemic penumbra and beyond for the treatment of ischemic stroke
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16. Single-Cell Imaging of Bioenergetic Responses to Neuronal Excitotoxicity and Oxygen and Glucose Deprivation
    Connolly, N. M. C., Dussmann, H., Anilkumar, U., Huber, H. J., Prehn, J. H. M. · 2014 · Journal of Neuroscience
17. Vitamin C Neuroprotection Against Dose-Dependent Glutamate-Induced Neurodegeneration in the Postnatal Brain
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18. “Preconditioning” with latrepirdine, an adenosine 5′-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1G93A mice
    Karen S. Coughlan, Mollie R. Mitchem, Marion C. Hogg, Jochen H.M. Prehn · 2014 · Neurobiology of Aging
19. Neuropharmacological Actions of Metformin in Stroke
    Jia Jia, Jian Gong Cheng, Jingshu Ni, Xuechu Zhen · 2015 · Current Neuropharmacology
20. A dual role for AMP ‐activated protein kinase (AMPK) during neonatal hypoxic–ischaemic brain injury in mice
    Catherine I. Rousset, Fiona C. Leiper, Anton Kichev, Pierre Gressèns, David Carling, Henrik Hagberg, Claire Thornton · 2015 · Journal of Neurochemistry
21. Small Molecule Adenosine 5′-Monophosphate Activated Protein Kinase (AMPK) Modulators and Human Diseases
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22. AMP-Activated Protein Kinase (AMPK) and Energy-Sensing in the Brain
    Santosh Ramamurthy, Gabriele V. Ronnett · 2012 · Experimental Neurobiology
23. Photoreceptor glucose metabolism determines normal retinal vascular growth
    Zhongjie Fu, Chatarina Löfqvist, Raffael Gi-Hwan Liegl, Zhongxiao Wang, Ye Sun, Yan Qing Gong, Chi‐Hsiu Liu, Steven S. Meng, Samuel B. Burnim, Ivana A. Arellano et al. · 2017 · EMBO Molecular Medicine
24. Physiological glucose is critical for optimized neuronal viability and AMPK responsiveness in vitro
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25. Mitochondrial Mechanisms of Neuroglobin’s Neuroprotection
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26. Mitochondria-containing extracellular vesicles from mouse vs. human brain endothelial cells for ischemic stroke therapy
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27. Proline restores mitochondrial function and reverses aging hallmarks in senescent cells
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28. Drosophila alicorn Is a Neuronal Maintenance Factor Protecting against Activity-Induced Retinal Degeneration
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29. Prospects of modeling poststroke epileptogenesis
    Doodipala Samba Reddy, Aamir A. Bhimani, Ramkumar Kuruba, Min Jung Park, Farida Sohrabji · 2016 · Journal of Neuroscience Research
30. Diabetes, stroke, and neuroresilience: looking beyond hyperglycemia
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31. The Microtubule-associated Protein EB1 Links AIM2 Inflammasomes with Autophagy-dependent Secretion
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32. Pre-stroke Metformin Treatment is Neuroprotective Involving AMPK Reduction
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33. Foetal-neonatal exposure of Di (2-ethylhexyl) phthalate disrupts ovarian development in mice by inducing autophagy
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34. Hypoxia Signaling Regulates Macrophage Migration Inhibitory Factor (MIF) Expression in Stroke
    Odysseus Zis, Si Zhang, Katerina Dorovini‐Zis, Lijuan Wang, Weihong Song · 2014 · Molecular Neurobiology
35. Effect of fasting on PPARγ and AMPK activity in adipocytes
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36. Globular adiponectin ameliorates metabolic insulin resistance via AMPK‐mediated restoration of microvascular insulin responses
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37. Promising use of metformin in treating neurological disorders: biomarker-guided therapies
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38. Reconsidering repurposing: long-term metformin treatment impairs cognition in Alzheimer’s model mice
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39. Mechanism of Zinc Excitotoxicity: A Focus on AMPK
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40. Effects of prolyl-hydroxylase inhibition and chronic intermittent hypoxia on synaptic transmission and plasticity in the rat CA1 and dentate gyrus
    Audrey M. Wall, Alan E. Corcoran, Ken D. O’Halloran, John Joseph O'Connor · 2013 · Neurobiology of Disease
41. Activation of AMP-activated protein kinase by tributyltin induces neuronal cell death
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42. Preconditioning induces sustained neuroprotection by downregulation of adenosine 5′-monophosphate-activated protein kinase
    Venugopal Reddy Venna, J. Li, Sharon E. Benashski, Sami Tarabishy, Louise D. McCullough · 2011 · Neuroscience
43. Global Reprogramming of Host Kinase Signaling in Response to Fungal Infection
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44. Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase
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45. When Hypothermia Meets Hypotension and Hyperglycemia: The Diverse Effects of Adenosine 5′-Monophosphate on Cerebral Ischemia in Rats
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46. AMPK-dependent and independent effects of AICAR and compound C on T-cell responses
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47. Neuroprotective effects of resveratrol against oxygen glucose deprivation induced mitochondrial dysfunction by activation of AMPK in SH-SY5Y cells with 3D gelatin scaffold
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48. Imaging Brain Activation
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49. RETRACTED: The importance of regulation of blood glucose levels through activation of peripheral 5′-AMP-activated protein kinase on ischemic neuronal damage
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50. Regulation of adenosine levels during cerebral ischemia
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51. Current evidence for AMPK activation involvement on resveratrol-induced neuroprotection in cerebral ischemia
    Narayana Pineda-Ramírez, Germán Fernando Gutiérrez Aguilar, Mónica Espinoza-Rojo, Penélope Aguilera · 2017 · Nutritional Neuroscience
52. To Use or Not to Use Metformin in Cerebral Ischemia: A Review of the Application of Metformin in Stroke Rodents
    Isaac Arbeláez-Quintero, Mauricio Palacios · 2017 · Stroke Research and Treatment
53. ATM at the crossroads of reactive oxygen species and autophagy
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54. Post-Stroke Hypothermia Provides Neuroprotection through Inhibition of AMP-Activated Protein Kinase
    Jun Li, Sharon E. Benashski, Louise D. McCullough · 2011 · Journal of Neurotrauma
55. Deletion of macrophage migration inhibitory factor worsens stroke outcome in female mice
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56. The Outcome of Renal Ischemia-Reperfusion Injury Is Unchanged in AMPK-β1 Deficient Mice
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57. The activation of adenosine monophosphate-activated protein kinase in rat hippocampus contributes to the rapid antidepressant effect of ketamine
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58. Hepatitis B virus (HBV) X protein-mediated regulation of hepatocyte metabolic pathways affects viral replication
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59. AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance
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60. Salvianolic acid A protects human SH-SY5Y neuroblastoma cells against H2O2-induced injury by increasing stress tolerance ability
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61. Stimulation of ovarian follicle growth after AMPK inhibition
    Xiaowei Lu, Song Guo, Yuan Cheng, Jae-hong Kim, Yi Feng, Yun Feng · 2017 · Reproduction
62. L-Cysteine-Derived H2S Promotes Microglia M2 Polarization via Activation of the AMPK Pathway in Hypoxia-Ischemic Neonatal Mice
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63. AMPK Signaling Regulates the Age-Related Decline of Hippocampal Neurogenesis
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64. Anti-flavivirus Properties of Lipid-Lowering Drugs
    Carlos Noe Farfán-Morales, Carlos Daniel Cordero‐Rivera, José Manuel Reyes-Ruíz, Arianna Mahely Hurtado-Monzón, Juan Fidel Osuna‐Ramos, Arely M. González‐González, Luis Adrián De Jesús‐González, Selvin Noé Palacios-Rápalo, Rosa María del Ángel · 2021 · Frontiers in Physiology
65. MiRNA-27b Regulates Angiogenesis by Targeting AMPK in Mouse Ischemic Stroke Model
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66. AMP‐activated protein kinase is involved in induction of protective autophagy in astrocytes exposed to oxygen‐glucose deprivation
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67. α-Synuclein binds and sequesters PIKE-L into Lewy bodies, triggering dopaminergic cell death via AMPK hyperactivation
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68. Modification of Endothelial Nitric Oxide Synthase through AMPK after Experimental Subarachnoid Hemorrhage
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69. Curcumin attenuates hyperglycaemia-mediated AMPK activation and oxidative stress in cerebrum of streptozotocin-induced diabetic rat
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70. Shengmai injection attenuates the cerebral ischemia/reperfusion induced autophagy via modulation of the AMPK, mTOR and JNK pathways
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71. Expression of Na–K–Cl cotransporter and edema formation are age dependent after ischemic stroke
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72. Ischemia-induced stimulation of Na-K-Cl cotransport in cerebral microvascular endothelial cells involves AMP kinase
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73. Inhibition of glycogen synthase kinase-3β enhances cognitive recovery after stroke: the role of TAK1
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74. N‐acetylgalactosaminyltransferase‐4 protects against hepatic ischemia/reperfusion injury by blocking apoptosis signal‐regulating kinase 1 N‐terminal dimerization
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75. Roles of electro-acupuncture in glucose metabolism as assessed by 18F-FDG/PET imaging and AMPKα phosphorylation in rats with ischemic stroke.
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76. The effect of age, sex and strains on the performance and outcome in animal models of stroke
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77. Inhibition of mi RNA ‐27b enhances neurogenesis via AMPK activation in a mouse ischemic stroke model
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78. AMPK protects proximal tubular cells from stress-induced apoptosis by an ATP-independent mechanism: potential role of Akt activation
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79. AMP-activated protein kinase contributes to zinc-induced neuronal death via activation by LKB1 and induction of Bim in mouse cortical cultures
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80. Ischemia-induced stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransport involves p38 and JNK MAP kinases
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81. Evaluation of the Neuroprotective Effect of Sirt3 in Experimental Stroke
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82. Dexmedetomidine pretreatment inhibits cerebral ischemia/reperfusion‑induced neuroinflammation via activation of AMPK
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83. The delivery of miR-21a-5p by extracellular vesicles induces microglial polarization via the STAT3 pathway following hypoxia-ischemia in neonatal mice
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84. Neuroprotective Potential of Mild Uncoupling in Mitochondria. Pros and Cons
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85. Suppression of 5′-AMP-activated protein kinase activity does not impair recovery of contractile function during reperfusion of ischemic hearts
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86. AMPK activates FOXO3a and promotes neuronal apoptosis in the developing rat brain during the early phase after hypoxia-ischemia
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87. Shizukaol D Isolated from Chloranthus japonicas Inhibits AMPK-Dependent Lipid Content in Hepatic Cells by Inducing Mitochondrial Dysfunction
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88. AMPK in the central nervous system: physiological roles and pathological implications
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89. Energy dysfunction in Huntington’s disease: insights from PGC-1α, AMPK, and CKB
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90. Adenosine monophosphate activated protein kinase inhibition is protective in both sexes after experimental stroke
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91. AMP‐activated protein kinase activator AICAR attenuates hypoxia‐induced murine fetal growth restriction in part by improving uterine artery blood flow
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92. Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia
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93. Pathophysiological Relevance of Forkhead Transcription Factors in Brain Ischemia
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94. New Candidate Targets of AMP-Activated Protein Kinase in Murine Brain Revealed by a Novel Multidimensional Substrate-Screen for Protein Kinases
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95. Pretreatment of rats with increased bioavailable berberine attenuates cerebral ischemia-reperfusion injury via down regulation of adenosine-5′monophosphate kinase activity
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96. A comparison of LKB1/AMPK/mTOR metabolic axis response to global ischaemia in brain, heart, liver and kidney in a rat model of cardiac arrest
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97. A pharmacological activator of AMP-activated protein kinase (AMPK) induces astrocyte stellation
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98. Early glycogen synthase kinase‐3β and protein phosphatase 2A independent tau dephosphorylation during global brain ischaemia and reperfusion following cardiac arrest and the role of the adenosine monophosphate kinase pathway
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99. TAK1 inhibition for treatment of cerebral ischemia
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100. Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity
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