Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke

Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide

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Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

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Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase

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5-Aminoimidazole-4-Carboxamide Ribonucleoside. A Specific Method for Activating AMP-Activated Protein Kinase in Intact Cells?

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Minireview: The AMP-Activated Protein Kinase Cascade: The Key Sensor of Cellular Energy Status

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A Role for AMP-Activated Protein Kinase in Contraction- and Hypoxia-Regulated Glucose Transport in Skeletal Muscle

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AMP‐activated protein kinase phosphorylation of endothelial NO synthase

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Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

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The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism

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Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase

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Anti-obesity effects of α-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase

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Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway

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AMP-activated protein kinase, super metabolic regulator

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AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the α2 isoform

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Role of the AMP-activated protein kinase in the cellular stress response

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Different Responses of Astrocytes and Neurons to Nitric Oxide: The Role of Glycolytically Generated ATP in Astrocyte Protection

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Characterization of the Role of AMP-Activated Protein Kinase in the Regulation of Glucose-Activated Gene Expression Using Constitutively Active and Dominant Negative Forms of the Kinase

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Direct Activation of AMP-activated Protein Kinase Stimulates Nitric-oxide Synthesis in Human Aortic Endothelial Cells*

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The Stimulation of Glycolysis by Hypoxia in Activated Monocytes Is Mediated by AMP-activated Protein Kinase and Inducible 6-Phosphofructo-2-kinase

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Neuroprotective Function of the PGE 2 EP2 Receptor in Cerebral Ischemia

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Intracellular ATP, a switch in the decision between apoptosis and necrosis

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Signaling of Cell Death and Cell Survival Following Focal Cerebral Ischemia: Life and Death Struggle in the Penumbra

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AMP-Activated Protein Kinase is Highly Expressed in Neurons in the Developing Rat Brain and Promotes Neuronal Survival Following Glucose Deprivation

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Ischemic Nitric Oxide and Poly (ADP-Ribose) Polymerase-1 in Cerebral Ischemia: Male Toxicity, Female Protection

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Intra-mitochondrial Poly(ADP-ribosylation) Contributes to NAD+ Depletion and Cell Death Induced by Oxidative Stress

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C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase*

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Physiological and Pathophysiological Roles of Nitric Oxide in the Central Nervous System

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The Regulation of AMP-Activated Protein Kinase by H2O2

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Apoptosis and brain ischaemia

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Cellular Distribution and Developmental Expression of AMP‐Activated Protein Kinase Isoforms in Mouse Central Nervous System

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C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity

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Identification of Phosphorylation Sites in AMP-activated Protein Kinase (AMPK) for Upstream AMPK Kinases and Study of Their Roles by Site-directed Mutagenesis*

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Akt as a mediator of cell death

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Postischemic Estrogen Reduces Hypoperfusion and Secondary Ischemia After Experimental Stroke

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Sustained activation of AMP‐activated protein kinase induces c‐Jun N‐terminal kinase activation and apoptosis in liver cells

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Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression

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NAD+ repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes

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Nitric Oxide Acutely Inhibits Neuronal Energy Production

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Poly(ADP-ribose) Polymerase-1 in the Nervous System

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Modulation by Peroxynitrite of Akt- and AMP-activated Kinase-dependent Ser1179 Phosphorylation of Endothelial Nitric Oxide Synthase

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Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase.

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The AMP‐activated protein kinase prevents ceramide synthesis de novo and apoptosis in astrocytes

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AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase

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AMP-activated protein kinase regulates gene expression by direct phosphorylation of nuclear proteins

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AICA riboside both activates AMP‐activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus

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C75, a Fatty Acid Synthase Inhibitor, Modulates AMP-activated Protein Kinase to Alter Neuronal Energy Metabolism

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The AMP‐Activated Protein Kinase Is Involved in the Regulation of Ketone Body Production by Astrocytes

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Apoptosis and Necrosis in Cerebrovascular Disease

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Ischemic Cerebral Edema

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5′-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells

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Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem

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Feeding active neurons: (re)emergence of a nursing role for astrocytes

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Hypoxic Preconditioning Increases Brain Glycogen and Delays Energy Depletion from Hypoxia-Ischemia in the Immature Rat

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BKCachannel activation by membrane-associated cGMP kinase may contribute to uterine quiescence in pregnancy

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Global brain water increases after experimental focal cerebral ischemia: Effect of hypertonic saline

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Pyruvate prevents cardiac dysfunction and AMP-activated protein kinase activation by hydrogen peroxide in isolated rat hearts

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AMPK in Health and Disease

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AMP-Activated Protein Kinase (AMPK) Controls the Aging Process via an Integrated Signaling Network

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Mitochondria, oxidative metabolism and cell death in stroke

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AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis

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AMPK inhibition in health and disease

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The CAMKK2-AMPK Kinase Pathway Mediates the Synaptotoxic Effects of Aβ Oligomers through Tau Phosphorylation

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Epigallocatechin-3-gallate (EGCG), A Green Tea Polyphenol, Suppresses Hepatic Gluconeogenesis through 5′-AMP-activated Protein Kinase

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AMPK: Lessons from transgenic and knockout animals

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AMPK in the brain: its roles in energy balance and neuroprotection

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AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer’s disease and other tauopathies

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Nerve growth factor activates autophagy in Schwann cells to enhance myelin debris clearance and to expedite nerve regeneration

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Middle Cerebral Artery Occlusion Model in Rodents: Methods and Potential Pitfalls

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AMP-activated Protein Kinase and p38 MAPK Activate O-GlcNAcylation of Neuronal Proteins during Glucose Deprivation

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AMPK: Potential Therapeutic Target for Ischemic Stroke

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Disruption of the Axon Initial Segment Cytoskeleton Is a New Mechanism for Neuronal Injury

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Neuroprotective Effects of Adenosine Monophosphate- Activated Protein Kinase Inhibition and Gene Deletion in Stroke

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Redox implications of AMPK-mediated signal transduction beyond energetic clues

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Roles of AMP-activated Protein Kinase in Alzheimer’s Disease

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Inhibition of AMP-activated protein kinase signaling alleviates impairments in hippocampal synaptic plasticity induced by amyloid β

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Metabolic Regulation of Neuronal Plasticity by the Energy Sensor AMPK

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Microglial IRF5-IRF4 regulatory axis regulates neuroinflammation after cerebral ischemia and impacts stroke outcomes

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Quercetin activates AMP‐activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol‐induced neurotoxicity

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Phospho-Dependent Functional Modulation of GABAB Receptors by the Metabolic Sensor AMP-Dependent Protein Kinase

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Epigallocatechin-3-Gallate Improves Acne in Humans by Modulating Intracellular Molecular Targets and Inhibiting P. acnes

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Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington’s disease

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Regulation of Glucose Transporter 3 Surface Expression by the AMP-Activated Protein Kinase Mediates Tolerance to Glutamate Excitation in Neurons

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A Novel Cell-permeable Antioxidant Peptide, SS31, Attenuates Ischemic Brain Injury by Down-regulating CD36

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Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease

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Effects of Metformin in Experimental Stroke

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Sex Differences in Caspase Activation After Stroke

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AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease

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Developing a head for energy sensing: AMP‐activated protein kinase as a multifunctional metabolic sensor in the brain

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Effects of AMP-Activated Protein Kinase in Cerebral Ischemia

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Functional recovery in aging mice after experimental stroke

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AMPK in the brain: its roles in glucose and neural metabolism

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mTOR/AMPK signaling in the brain: Cell metabolism, proteostasis and survival

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Role of the energy sensor AMP-activated protein kinase in renal physiology and disease

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Activation of Cannabinoid CB2 Receptor–Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury

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SIRT3 Protects Against Acute Kidney Injury via AMPK/mTOR-Regulated Autophagy

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Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke

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AMP kinase–mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

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CaMKII in cerebral ischemia

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Emerging therapeutic interventions against noise-induced hearing loss

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Sex Differences in Ischemic Stroke Sensitivity Are Influenced by Gonadal Hormones, Not by Sex Chromosome Complement

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AMP-activated protein kinase (AMPK) activating agents cause dephosphorylation of Akt and glycogen synthase kinase-3

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Expanding roles for AMP‐activated protein kinase in neuronal survival and autophagy

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Molecular Mechanisms of Neonatal Brain Injury

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Apelin Attenuates Oxidative Stress in Human Adipocytes

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Transient focal cerebral ischemia induces long-term cognitive function deficit in an experimental ischemic stroke model

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Caloric Restriction Stimulates Revascularization in Response to Ischemia via Adiponectin-mediated Activation of Endothelial Nitric-oxide Synthase

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Interleukin-11 treatment protected against cerebral ischemia/reperfusion injury

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Activation of AMP-activated protein kinase by metformin protects against global cerebral ischemia in male rats: Interference of AMPK/PGC-1α pathway

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Resveratrol Activates Neuronal Autophagy Through AMPK in the Ischemic Brain

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AMP-activated protein kinase activity during metabolic rate depression in the hypoxic goldfish, Carassius auratus

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Targeting AMPK in Diabetes and Diabetic Complications: Energy Homeostasis, Autophagy and Mitochondrial Health

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AMP-Activated Protein Kinase (AMPK) Molecular Crossroad for Metabolic Control and Survival of Neurons

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Adiponectin deficiency exacerbates cardiac dysfunction following pressure overload through disruption of an AMPK-dependent angiogenic response

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Ischemic Preconditioning Provides Neuroprotection by Induction of AMP-Activated Protein Kinase-Dependent Autophagy in a Rat Model of Ischemic Stroke

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Berberine: Pathways to protect neurons

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AMP-activated protein kinase is activated in Parkinson’s disease models mediated by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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Reduced Activity of AMP-Activated Protein Kinase Protects against Genetic Models of Motor Neuron Disease

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Mitochondrial dysfunction and Parkinson disease: a Parkin–AMPK alliance in neuroprotection

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Unpredictable chronic mild stress induces anxiety and depression-like behaviors and inactivates AMP-activated protein kinase in mice

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Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation

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Adenosine monophosphate-activated protein kinase overactivation leads to accumulation of α-synuclein oligomers and decrease of neurites

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(ADP-ribose) polymerase 1 and AMP-activated protein kinase mediate progressive dopaminergic neuronal degeneration in a mouse model of Parkinson’s disease

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Insulin as a Bridge between Type 2 Diabetes and Alzheimer Disease – How Anti-Diabetics Could be a Solution for Dementia

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O-GlcNAc Protein Modification in Cancer Cells Increases in Response to Glucose Deprivation through Glycogen Degradation

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The cystathionine β-synthase/hydrogen sulfide pathway contributes to microglia-mediated neuroinflammation following cerebral ischemia

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Synaptic Activity and Bioenergy Homeostasis: Implications in Brain Trauma and Neurodegenerative Diseases

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Metformin improves cardiac function in rats via activation of AMP‐activated protein kinase

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Berberine inhibits platelet-derived growth factor-induced growth and migration partly through an AMPK-dependent pathway in vascular smooth muscle cells

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An Integrated and Unifying Hypothesis for the Metabolic Basis of Sporadic Alzheimer's Disease

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Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots

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Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms

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Resveratrol activates AMPK and suppresses LPS-induced NF-κB-dependent COX-2 activation in RAW 264.7 macrophage cells

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Regulation of AMP-activated protein kinase activity by G-protein coupled receptors: Potential utility in treatment of diabetes and heart disease

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Hydrogen-rich saline promotes microglia M2 polarization and complement-mediated synapse loss to restore behavioral deficits following hypoxia-ischemic in neonatal mice via AMPK activation

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A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of β-caryophyllene, a dietary cannabinoid

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AMPK: The key to ischemia‐reperfusion injury

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AMPK-induced activation of Akt by AICAR is mediated by IGF-1R dependent and independent mechanisms in acute lymphoblastic leukemia

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Role of 5′-Adenosine Monophosphate-Activated Protein Kinase in Cell Survival and Death Responses in Neurons

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AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells

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Poly(ADP-ribose)polymerase-1 hyperactivation in neurodegenerative diseases: The death knell tolls for neurons

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Adiponectin protects rat hippocampal neurons against excitotoxicity

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Structural basis for compound C inhibition of the human AMP-activated protein kinase α2 subunit kinase domain

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Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma

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Upregulation of fibronectin and the α5β1 and αvβ3 integrins on blood vessels within the cerebral ischemic penumbra

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The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe Disease

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AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease

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