The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Compensatory Roles of Foxa1 and Foxa2 during Lung Morphogenesis
Open accessAbstract
Foxa1 and Foxa2 are closely related family members of the Foxa group of transcription factors that are coexpressed in subsets of respiratory epithelial cells throughout lung morphogenesis. Shared patterns of expression, conservation of DNA binding, and transcriptional activation domains indicate that they may serve complementary functions in the regulation of gene expression during lung morphogenesis. Whereas branching morphogenesis of the fetal lung occurs normally in the Foxa2Delta/Delta and Foxa1-/- mice, deletion of both Foxa1 and Foxa2 (in Foxa2Delta/Delta, Foxa1-/- mice) inhibited cell proliferation, epithelial cell differentiation, and branching. Dilation of terminal lung tubules and decreased branching were observed as early as embryonic day 12.5. Foxa1 and Foxa2 regulated Shh (sonic hedgehog) and Shh-dependent genes in the respiratory epithelial cells that influenced the expression of genes in the pulmonary mesenchyme that are required for branching morphogenesis. Epithelial cell differentiation, as indicated by lack of expression of surfactant protein B, surfactant protein C, the Clara cell secretory protein, and Foxj1, was inhibited. Foxa family members regulate signaling and transcriptional programs required for morphogenesis and cell differentiation during formation of the lung.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Ang, S.-L., Wierda, A., Wong, D., Stevens, K. A., Cascio, S., Rossant, J., & Zaret, K. S. (1993) · Development · doi:10.1242/dev.119.4.1301 · Cited by 618
Self-citation
Cited by
Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development
Morrisey, E. E., & Hogan, B. L. M. (2010) · Developmental Cell · doi:10.1016/j.devcel.2009.12.010 · Cited by 964
Lung development: orchestrating the generation and regeneration of a complex organ
Herriges, M., & Morrisey, E. E. (2014) · Development · doi:10.1242/dev.098186 · Cited by 613
DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning
Angermueller, C., Lee, H. J., Reik, W., & Stegle, O. (2017) · Genome Biology · doi:10.1186/s13059-017-1189-z · Cited by 536
Hinds, D. A., McMahon, G., Kiefer, A. K., Do, C. B., Eriksson, N., Evans, D. M., St Pourcain, B., Ring, S. M., Mountain, J. L., Francke, U., et al. (2013) · Nature Genetics · doi:10.1038/ng.2686 · Cited by 246
Foxa1 and Foxa2 regulate bile duct development in mice
Li, Z., White, P., Tuteja, G., Rubins, N., Sackett, S., & Kaestner, K. H. (2009) · Journal of Clinical Investigation · doi:10.1172/jci38201 · Cited by 131
Self-citation
Metadata
- Authors
- Wan, H., Dingle, S., Xu, Y., Besnard, V., Kaestner, K. H., Ang, S.-L., Wert, S., Stahlman, M. T., & Whitsett, J. A.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2005-04
- Volume
- 280
- Issue
- 14
- Pages
- 13809-13816
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2024931422
- Cited by
- 278
- References
- 1
- FWCI
- 12.33
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Compensatory Roles of Foxa1 and Foxa2 during Lung Morphogenesis. https://app.cochat.ai/papers/10.1074/jbc.m414122200
- The paper
- Wan, H., Dingle, S., Xu, Y., Besnard, V., Kaestner, K. H., Ang, S.-L., Wert, S., Stahlman, M. T., & Whitsett, J. A. (2005). Compensatory Roles of Foxa1 and Foxa2 during Lung Morphogenesis. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.m414122200
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
