The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A R2R3 Type MYB Transcription Factor Is Involved in the Cold Regulation of CBF Genes and in Acquired Freezing Tolerance
Open accessAbstract
Cold temperatures trigger the expression of the CBF family of transcription factors, which in turn activate many downstream genes that confer freezing tolerance to plants. It has been shown previously that the cold regulation of CBF3 involves an upstream bHLH-type transcription factor, ICE1. ICE1 binds to the Myc recognition sequences in the CBF3 promoter. Apart from Myc recognition sequences, CBF promoters also have Myb recognition sequences. We report here that the Arabidopsis MYB15 is involved in cold-regulation of CBF genes and in the development of freezing tolerance. The MYB15 gene transcript is up-regulated by cold stress. The MYB15 protein interacts with ICE1 and binds to Myb recognition sequences in the promoters of CBF genes. Overexpression of MYB15 results in reduced expression of CBF genes whereas its loss-of-function leads to increased expression of CBF genes in the cold. The myb15 mutant plants show increased tolerance to freezing stress whereas its overexpression reduces freezing tolerance. Our results suggest that MYB15 is part of a complex network of transcription factors controlling the expression of CBFs and other genes in response to cold stress.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Liu, Q., Kasuga, M., Sakuma, Y., Abe, H., Miura, S., Yamaguchi-Shinozaki, K., & Shinozaki, K. (1998) · The Plant Cell · doi:10.1105/tpc.10.8.1391 · Cited by 3,044
Stockinger, E. J., Gilmour, S. J., & Thomashow, M. F. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.3.1035 · Cited by 1,807
Cited by
MYB transcription factors in Arabidopsis
Dubos, C., Stracke, R., Grotewold, E., Weisshaar, B., Martin, C., & Lepiniec, L. (2010) · Trends in Plant Science · doi:10.1016/j.tplants.2010.06.005 · Cited by 4,865
Arisz, S. A., van Wijk, R., Roels, W., Zhu, J.-K., Haring, M. A., & Munnik, T. (2013) · Frontiers in Plant Science · doi:10.3389/fpls.2013.00001 · Cited by 1,922
Self-citationImpact of Climate Change on Crops Adaptation and Strategies to Tackle Its Outcome: A Review
Raza, A., Razzaq, A., Mehmood, S. S., Zou, X., Zhang, X., Lv, Y., & Xu, J. (2019) · Plants · doi:10.3390/plants8020034 · Cited by 1,762
Lin-Wang, K., Bolitho, K., Grafton, K., Kortstee, A., Karunairetnam, S., McGhie, T. K., Espley, R. V., Hellens, R. P., & Allan, A. C. (2010) · BMC Plant Biology · doi:10.1186/1471-2229-10-50 · Cited by 699
Saibo, N. J. M., Lourenço, T., & Oliveira, M. M. (2009) · Annals of Botany · doi:10.1093/aob/mcn227 · Cited by 483
Metadata
- Authors
- Agarwal, M., Hao, Y., Kapoor, A., Dong, C.-H., Fujii, H., Zheng, X., & Zhu, J.-K.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2006-12
- Volume
- 281
- Issue
- 49
- Pages
- 37636-37645
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W2142269897
- Cited by
- 949
- References
- 2
- FWCI
- 18.98
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A R2R3 Type MYB Transcription Factor Is Involved in the Cold Regulation of CBF Genes and in Acquired Freezing Tolerance. https://app.cochat.ai/papers/10.1074/jbc.m605895200
- The paper
- Agarwal, M., Hao, Y., Kapoor, A., Dong, C.-H., Fujii, H., Zheng, X., & Zhu, J.-K. (2006). A R2R3 Type MYB Transcription Factor Is Involved in the Cold Regulation of CBF Genes and in Acquired Freezing Tolerance. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.m605895200
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
