Role for KAP1 Serine 824 Phosphorylation and Sumoylation/Desumoylation Switch in Regulating KAP1-mediated Transcriptional Repression

Li, Xu, Lee, Yung-Kang, Jeng, Jen-Chong, Yen, Yun, Schultz, David C., Shih, Hsiu-Ming, Ann, David K.·2007·Journal of Biological Chemistry

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Items 101–169 of 169

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    Ye Xu, Chang Xu, Brendan D. Price · 2012 · Progress in molecular biology and translational science
  2. Phosphatases reverse p53-mediated cell cycle checkpoints
    Lawrence A. Donehower · 2014 · Proceedings of the National Academy of Sciences
  3. Characterization of interaction between Trim28 and YY1 in silencing proviral DNA of Moloney murine leukemia virus
    Andreia Lee, Oya Cingöz, Yosef Sabo, Stephen P. Goff · 2018 · Virology
  4. TRIM28/KAP1 regulates senescence
    Joana Santos, Jesús Gil · 2014 · Immunology Letters
  5. Repression of interrupted and intact rDNA by the SUMO pathway in drosophila melanogaster
    Luo, Yicheng, Fefelova, Elena, Ninova, Maria, Chen, Yung-Chia Ariel, Aravin, Alexei A · 2020 · eLife
  6. KRAB zinc-finger proteins localise to novel KAP1-containing foci that are adjacent to PML nuclear bodies
    S. Briers, C. Crawford, W. Bickmore, Heidi G. E. Sutherland · 2009 · Journal of Cell Science
  7. Inhibition of CDK1 activity by sumoylation
    Yuxuan Xiao, Benjamin Lucas, Elana Molcho, Tania Schiff, Margarita Vigodner · 2016 · Biochemical and Biophysical Research Communications
  8. Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity
    Yasukiyo Yoshioka, Daisuke Namiki, 牧内麻緒, Kouichi Sugaya, Jun‐ichi Onose, Hitoshi Ashida, Naoki Abe · 2016 · Bioorganic & Medicinal Chemistry Letters
  9. KAP1 is a Novel Substrate for the Arginine Methyltransferase PRMT5
    Roberta Di Caprio, Michela Ciano, Giorgia Montano, Paola Costanzo, Elena Cesaro · 2015 · Biology
  10. Buried territories: heterochromatic response to DNA double-strand breaks
    Yi-Li Feng, Ji-Feng Xiang, Na Kong, Xiujun Cai, Anyong Xie · 2016 · Acta Biochimica et Biophysica Sinica
  11. PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma
    Abdallah Gaballa, Anneli Gebhardt-Wolf, Bastian Krenz, Greta Mattavelli, Mara John, Giacomo Cossa, Silvia Andreani, Christina Schülein‐Völk, Francisco Montesinos, Raphael Silveira Vidal et al. · 2024 · Nature Communications
  12. The Complex Role of the ZNF224 Transcription Factor in Cancer.
    Elena Cesaro, Gaetano Sodaro, Giorgia Montano, M. Grosso, A. Lupo, P. Costanzo · 2017 · Advances in Protein Chemistry and Structural Biology
  13. Differential control of retrovirus silencing in embryonic cells by proteasomal regulation of the ZFP809 retroviral repressor
    Cheng Wang, Stephen P. Goff · 2017 · Proceedings of the National Academy of Sciences
  14. The lncRNA BORG: a novel inducer of TNBC metastasis, chemoresistance, and disease recurrence
    Alex J. Gooding, Kimberly A. Parker, Saba Valadkhan, William P. Schiemann · 2019 · Journal of Cancer Metastasis and Treatment
  15. Potential Roles of Intrinsic Disorder in Maternal-Effect Proteins Involved in the Maintenance of DNA Methylation
    Hongliang Liu, Qing Wei, Chen-Yang Huang, Yong Zhang, Ze-Kun Guo · 2017 · International Journal of Molecular Sciences
  16. Inhibition of ATM-directed antiviral responses by HIV-1 Vif
    Hoi Tong Wong, Adeline M. Luperchio, Sean Riley, Daniel J. Salamango · 2023 · PLoS Pathogens
  17. Clinical Utility of KAP-1 Expression in Thyroid Lesions
    Mariana Bonjiorno Martins, Marjory Alana Marcello, Elaine Cristina Morari, Lucas Leite Cunha, Fernando Augusto Soares, José Vassallo, Laura Sterian Ward · 2013 · Endocrine Pathology
  18. The transcription intermediary factor 1β coactivates the androgen receptor.
    Nora Van Tilborgh, Lien Spans, Christine Helsen, Liesbeth Clinckemalie, Vanessa Dubois, E. Lerut, Steven Boonen, Dirk Vanderschueren, Frank Claessens · 2013 · PubMed
  19. The deubiquitinase Usp27x as a novel regulator of cFLIPL protein expression and sensitizer to death-receptor-induced apoptosis
    Manuel Nico Dold, Xiulin Ng, Claudia Alber, Ian Edward Gentle, Georg Alexander Häcker, Arnim Weber · 2022 · APOPTOSIS
  20. Protein phosphatase 4 regulatory subunit 2 (PPP4R2) is recurrently deleted in acute myeloid leukemia and required for efficient DNA double strand break repair
    Julia Herzig, Lars Bullinger, Alpaslan Tasdogan, Philipp Zimmermann, Martin Schlegel, Veronica Teleanu, Daniela Weber, Frank G. Rücker, Peter Paschka, Anna Dolnik et al. · 2017 · Oncotarget
  21. Disruption of RING and PHD Domains of TRIM28 Evokes Differentiation in Human iPSCs
    Sylwia Mazurek, Urszula Oleksiewicz, P. Czerwińska, J. Wróblewska, Marta Klimczak, M. Wiznerowicz · 2021 · Cells
  22. TRIM28 suppresses cancer stem-like characteristics in gastric cancer cells through Wnt/β-catenin signaling pathways
    Tingting Ning, Mengran Zhao, Nan Zhang, Zhaoqing Wang, Shutian Zhang, Mo Liu, Shengtao Zhu · 2023 · Experimental Biology and Medicine
  23. Dynamic Regulation of Steroid Hormone Receptor Transcriptional Activity by Reversible SUMOylation
    Todd Philip Knutson, Carol Ann Lange · 2013 · Vitamins and hormones
  24. Assessment of the role of translationally controlled tumor protein 1 (TPT1/TCTP) in breast cancer susceptibility and ATM signaling
    Katharina Neuhäuser, Leonie Maria Küper, Hans Christiansen, Natalia Viktorovna Bogdanova · 2019 · Clinical and Translational Radiation Oncology
  25. Proteomic Analysis of Nuclei Isolated from Cancer Cell Lines Treated with Indenoisoquinoline NSC 724998, a Novel Topoisomerase I Inhibitor
    Bingnan Han, Luke H. Stockwin, Chad N. Hancock, Sherry X. Yu, Melinda G. Hollingshead, Dianne L. Newton · 2010 · Journal of Proteome Research
  26. Role of Protein Phosphatase 1 and Inhibitor of Protein Phosphatase 1 in Nitric Oxide–Dependent Inhibition of the DNA Damage Response in Pancreatic β-Cells
    Bryndon J. Oleson, Aaron Naatz, Sarah C. Proudfoot, Chay Teng Yeo, John A. Corbett · 2018 · Diabetes
  27. Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells
    Yao-Jen Chang, Steven Lin, Zhifu Kang, Bin-Jon Shen, Wen-Hai Tsai, Wen‐Ching Chen, Hsin-Pin Lu, Yu-Lun Su, Shu‐Jen Chou, Shu‐Yu Lin et al. · 2023 · International Journal of Molecular Sciences
  28. SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes
    Baira K. Godneeva, Maria Ninova, Katalin Fejes Tóth, Alexei A. Aravin · 2023 · eLife
  29. SUMO wrestling with Ras
    Haibo Zhang, Ji Luo · 2016 · Small GTPases
  30. Cocaine-Induced DNA-Dependent Protein Kinase Relieves RNAP II Pausing by Promoting TRIM28 Phosphorylation and RNAP II Hyperphosphorylation to Enhance HIV Transcription
    Adhikarimayum Lakhikumar Sharma, Priya Tyagi, Meenata Khumallambam, Mudit Tyagi · 2024 · Cells
  31. A novel role of TRIM28 B box domain in L1 retrotransposition and ORF2p-mediated cDNA synthesis
    Qianhui Du, Emily C. Stow, Dawn LaCoste, Benjamin Freeman, Melody Baddoo, Afzaal M. Shareef, Kyle M. Miller, Victoria P. Belancio · 2023 · Nucleic Acids Research
  32. The Herculean task of killing cancer cells: Suppression of FOXO3A in acute leukemia involves a hydra of multiple survival kinases
    Peter P. Ruvolo · 2012 · Cell Cycle
  33. Coordinate to Guard: Crosstalk of Phosphorylation, Sumoylation, and Ubiquitylation in DNA Damage Response
    Ching‐Ying Kuo, Christine Shieh, Fei Cai, David Kong Ann · 2012 · Frontiers in Oncology
  34. Analyzing Heterochromatic DNA Double Strand Break (DSB) Repair in Response to Ionizing Radiation
    Karolin Klement, Aaron A. Goodarzi · 2017 · Methods in molecular biology
  35. Sumo Control
    K. Maderbock, Andrea Pichler · 2010 · Sub-cellular biochemistry/Subcellular biochemistry
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  38. [Dacron and polytetrafluoroethylene aorto-bifemoral grafts].
    Lazar B Davidovic, Slobodan I. Lotina, Dusan M. Kostic, Ilija Cinara, Slobodan D. Cvetkovic, P L Stojanović, L B Velimirović, Dragan M. Markovic, Siniša Pejkić, G Pavlović · 1997 · PubMed
  39. Differential Expression of Seven De-sumoylation Enzymes (SENPs) in Major Ocular Tissues of Mouse Eye
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  42. BRCA1 and BRCA2: Role in the DNA Damage Response, Cancer Formation and Treatment
    Kienan I. Savage, Denis Paul Harkin · 2009 · Springer eBooks
  43. Cellular SUMO-specific proteases regulate HAdV-C5 E1B-55K SUMOylation and virus-induced cell transformation
    Wing-Hang Ip, Marie Fiedler, Britta Gornott, Malte Morische, Luca D. Bertzbach, Thomas Dobner · 2024 · Frontiers in Cellular and Infection Microbiology
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  45. Exonuclease-1 interacts with the transcriptional co-repressor KAP1
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  46. DNA damage signaling, cell reprogramming, and differentiation
    Mikio Shimada, Tomoko Miyake · 2022 · Elsevier eBooks
  47. SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes
    Baira K. Godneeva, Maria Ninova, Katalin Fejes Tóth, Alexei A. Aravin · 2023 · eLife
  48. Novel functions of the MOZ double PHD finger domain
    S.E. Deeves · 2012 · Nottingham ePrints (University of Nottingham)
  49. Regulation of cellular signalling pathways by Adenovirus
    Natalie A. Forrester · 2012 · University of Birmingham Institutional Research Archive (University of Birmingham)
  50. Transcriptional silencing of endogenous retroviruses by the novel lysine methyltransferase co-repressor hnRNP K
    Thompson, Peter Jeffrey · 2015 · cIRcle (University of British Columbia)
  51. SENP1 and SENP2 Peptidases
    Edward T.H. Yeh, Hong Dou · 2012 · Handbook of Proteolytic Enzymes
  52. Interactions between the adeno-associated virus replication proteins and host cellular factors
    Sarah C. Smith · 2016
  53. The histone methyltransferase DOT1L is required for DNA damage recognition and repair
    Sanjay Kumar Raul · 2017
  54. Regulation Of Retroviral Silencing In Different Cell Types
    Cheng Wang · 2015
  55. DNA-PK facilitates HIV transcription by regulating the activity of RNA polymerase II and the recruitment of transcription machinery at HIV LTR
    Sonia Zicari, Geetaram Sahu, Larisa Dubrovsky, Lin Sun, Han Yue, Tejaswi Jada, Alex Ochem, Michael Bukrinsky, Gary Leonard Simon, Mudit Tyagi · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  56. Mutation of TRIM28-Lys304 to Gln Attenuates its Interaction with KRAB-ZNFs and Promotes Differentiation of Erythroleukemic K562 Cells
    Yao-Jen Chang, Steven Lin, Zhifu Kang, Bin-Jon Shen, Wen-Hai Tsai, Wen‐Ching Chen, Hsin-Pin Lu, Sheng‐Wei Lin, Shu‐Yu Lin, Shu‐Jen Chou et al. · 2020 · Research Square
  57. SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes
    Baira K. Godneeva, Maria Ninova, Katalin Fejes Tóth, Alexei A. Aravin · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  58. SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes
    Baira K. Godneeva, Maria Ninova, Katalin Fejes Tóth, Alexei A. Aravin · 2023 · eLife
  59. SUMOylation of Bonus, the Drosophila homolog of Transcription Intermediary Factor 1, safeguards germline identity by recruiting repressive chromatin complexes to silence tissue-specific genes
    Baira K. Godneeva, Maria Ninova, Katalin Fejes Tóth, Alexei A. Aravin · 2023 · eLife
  60. Development of transposon-mediated gene delivery systems with improved safety for the use in gene and cell therapy
    Maximilian Amberger · 2023
  61. Additional file 1 of RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment
    Park, Han-Hee, Kim, Hwa-Ryeon, Park, Sang-Yeong, Hwang, Sung-Min, Sun Mi Hong, Sangwook Park, Kang, Ho Chul, Michael John Morgan, Cha, Jong-Ho, Dakeun Lee et al. · 2021 · Figshare
  62. La delta-lactoferrine : un facteur de transcription régulé par SUMOylation
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  63. Etude de la réparation des cassures double-brin de l'ADN dans les cellules souches du muscle squelettique et leurs progéniteurs
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  65. KAP1 : un nouveau facteur répresseur de la transcription du VIH-1
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  69. BindingDB Entry 50010234: Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity.
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