PGC-1α Integrates Insulin Signaling, Mitochondrial Regulation, and Bioenergetic Function in Skeletal Muscle

Pagel-Langenickel, Ines, Bao, Jianjun, Joseph, Joshua J., Schwartz, Daniel R., Mantell, Benjamin S., Xu, Xiuli, Raghavachari, Nalini, Sack, Michael N.·2008·Journal of Biological Chemistry

Cited by (124)

Items 101–124 of 124

  1. miR-193b-3p/ PGC-1α pathway regulates an insulin dependent anti-inflammatory response in Parkinson's disease
    Lucia Mesarosova, Mirte Scheper, Anand M. Iyer, Jasper J. Anink, James Dominic Mills, Eleonora Aronica · 2024 · Neurobiology of Disease
  2. Ursolic Acid-Regulated Energy Metabolism—Reliever or Propeller of Ultraviolet-Induced Oxidative Stress and DNA Damage?
    Yuan‐Hao Lee, Youping Sun, Randolph D. Glickman · 2014 · Proteomes
  3. Rab4a signaling unmasks a pivotal link between myocardial homeostasis and metabolic remodeling in the diabetic heart
    Michael N. Sack · 2010 · Journal of Molecular and Cellular Cardiology
  4. Impact of Bariatric Surgery on the Expression of Fertility-Related Genes in Obese Women: A Systematic Review of LEP, LEPR, MC4R, FTO, and POMC
    Charalampos Voros, Ioakeim Sapantzoglou, Aristotelis-Marios Koulakmanidis, Diamantis Athanasiou, Despoina Mavrogianni, Kyriakos Bananis, Antonia Iliana Athanasiou, Aikaterini V. Athanasiou, George K. Papadimas, Ioannis Papapanagiotou et al. · 2025 · International Journal of Molecular Sciences
  5. Extracellular vesicles from obese and diabetic mouse plasma alter C2C12 myotube glucose uptake and gene expression
    Christopher R. Pitzer, Hector G. Paez, Peter J. Ferrandi, Junaith Shaik Mohamed, Stephen E. Alway · 2024 · Physiological Reports
  6. Modifying muscle metabolic dysregulation in inclusion body myositis with pioglitazone: a single-arm trial
    Brittany L. Adler, Michael R. Bene, Cissy Zhang, Conrad Say, Pratik Khare, Christopher A. Mecoli, Eleni Tiniakou, Julie J. Paik, Tae Chung, Erika Darrah et al. · 2026 · Nature Communications
  7. Thyroid hormones and metabolic flexibility: tissue-specific control of energy homeostasis
    Annunziata Gaetana Cicatiello, Caterina Miro, Serena Sagliocchi, Annarita Nappi, Monica Dentice · 2026 · Frontiers in Physiology
  8. Mitochondrial Dysfunction in Insulin Insensitivity and Type 2 Diabetes and New Insights for Their Prevention and Management
    Chih‐Hao Wang, Kun-Ting Chi, Yau‐Huei Wei · 2012 · InTech eBooks
  9. Immunometabolism of IRF4 in adipose, muscle, and immune cells influences obesity and MASLD
    Daniel M. Marko, Jonathan D. Schertzer · 2026 · American Journal of Physiology-Endocrinology and Metabolism
  10. Peppermint oil prevented oxidative stress in experimental animal – induced acute single bout of eccentric exercise (ASBEE) : study on blood catalase and hydrogen peroxide (H 2 O 2) and glucose transporter-4 (GLUT-4) expression on the muscle cells
    Dewi Aryanti, Mae Sri Hartati Wahyuningsih, Denny Agustiningsih · 2018 · Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
  11. Energy expenditure related biomarkers following bariatric surgery: a prospective six-month cohort study
    Mahsa Hatami, Mohammad Hassan Javanbakht, Neda Haghighat, Zahra Sohrabi, Rahman Yavar, Abdolreza Pazouki, Gholamreza Mohammadi Farsani · 2024 · BMC Surgery
  12. ROLES OF PGC-1α/PPARS PATHWAY IN REGULATING INSULIN SENSITIVITY IN MOUSE SKELETAL MUSCLE CELLS UNDER PROLONGED HYPOXIA (Roles of PGC-1α/PPARs in insulin sensitivity regulation under hypoxia) (Thesis format: Monograph)
    Yunyan Zhang · 2012 · Scholarship@Western (Western University)
  13. ROLES OF PGC-1α/PPARS PATHWAY IN REGULATING INSULIN SENSITIVITY IN MOUSE SKELETAL MUSCLE CELLS UNDER PROLONGED HYPOXIA (Roles of PGC-1α/PPARs in insulin sensitivity regulation under hypoxia) (Thesis format: Monograph)
    Yunyan Zhang · 2012
  14. The Drosophila PGC-1 homologue Spargel coordinates mitochondrial biogenesis to insulin-signalling
    Stefanie K. Tiefenböck · 2009 · Repository for Publications and Research Data (ETH Zurich)
  15. Angewandte Biochemie VI: Insulinsensitivität
    Christoph Michalk · 2019 · Springer eBooks
  16. Cardiac Energy Metabolism in Heart Failure Associated with Obesity and Diabetes
    Gary D. Lopaschuk · 2014 · Springer eBooks
  17. Mitophagy in Heart Failure: A Selective Autophagic Degradation of Mitochondria
    Kai‐Chun Yang · 2009
  18. Current World Literature
    2009 · Current Opinion in Lipidology
  19. Biochanin A has anti-inflammatory effects on diet-induced obesity and ovariectomy in mice
    Jéssica Maria Dantas Araújo Aragão, Luana Heimfarth, Wemerson de Santana Neres, Franciel Batista Félix, Patrícia Rabelo dos Santos, Fabiula Francisca de Abreu, Luana Mendonça Cercato, Ana Carla Silva Nascimento, Alan Bruno Silva Vasconcelos, Rosilene Calazans Soares et al. · 2024 · Research Square
  20. Molecular Pathways in Diabetic Cardiomyopathy and the Role of Anti-hyperglycemic Drugs Beyond Their Glucose Lowering Effect
    Jie-Eun Lee, Byung Gyu Kim, Jong Chul Won · 2025 · Journal of Lipid and Atherosclerosis
  21. Disruption of the retinoid X receptor–PPAR-γ axis is associated with appetite hormone dysregulation and cognitive dysfunction: A cross-sectional study of adolescents with first-episode bipolar disorder
    Mu‐Hong Chen, Ju-Wei Hsu, Li-Chi Chen, Shih‐Jen Tsai, Ya‐Mei Bai · 2025 · Journal of Affective Disorders
  22. Adaptations environnementales de la protéosynthèse et de la protéolyse dans le muscle de poulet : voies de signalisation impliquées
    S. Boussaid-Om Ezzine · 2011 · theses.fr (ABES)
  23. South African Herbal Teas and Diabetes‐Mediated Mitochondrial Dysfunction: Emerging Evidence and Mechanistic Insights
    Shanika Reddy, Naeem Sheik Abdul, Taskeen Fathima Docrat, Jeanine Lucasta Marnewick · 2026 · Journal of Food Science
  24. Neuroprotective Role of PGC-1α Against Oxidative Stress and Mitochondrial Dysfunction in Chronic Pain Pathophysiology: A Review
    Mubarak Hussaini Ahmad, Garba M. Khalid, Yau Adamu, Mustapha Mohammed, Abubakar Ibrahim Jatau, Ismaeel U. Yunusa · 2026 · Biomedicines