The DOI matches its Crossref record; 100 of the 100 references it cites were found in a registry or an index.
GATA Switches as Developmental Drivers
Open accessAbstract
Transcriptional networks orchestrate complex developmental processes. Such networks are commonly instigated by master regulators of development. Considerable progress has been made in elucidating GATA factor-dependent genetic networks that control blood cell development. GATA-2 is required for the genesis and/or function of hematopoietic stem cells, whereas GATA-1 drives the differentiation of hematopoietic progenitors into a subset of the blood cell lineages. GATA-1 directly represses Gata2 transcription, and this involves GATA-1-mediated displacement of GATA-2 from chromatin, a process termed a GATA switch. GATA switches occur at numerous loci with critical functions, indicating that they are widely utilized developmental control tools.
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Self-citation
Metadata
- Authors
- Bresnick, E. H., Lee, H.-Y., Fujiwara, T., Johnson, K. D., & Keles, S.
- Venue
- Journal of Biological Chemistry
- Publisher
- Elsevier BV
- Published
- 2010-10
- Volume
- 285
- Issue
- 41
- Pages
- 31087-31093
- ISSN
- 0021-9258 (ISSN-L)
- OpenAlex
- W1985739269
- Cited by
- 269
- References
- 100
- FWCI
- 6.85
- Type
- journal article
- Language
- en
- Open access
- hybrid
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