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The M2 Proton Channels of Influenza A and B Viruses

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Pinto, Lawrence H., Lamb, Robert A.·2006·Journal of Biological Chemistry

Abstract

Influenza A virus and influenza B virus are two different enveloped, negative stranded RNA viruses that cause epidemic infections. The virion (virus particle) of each virus contains a small integral membrane protein (A/M2 and BM2, respectively) that functions as a proton channel and is essential to viral replication. These proton channels are of interest because they are among the smallest bona fide ion channel proteins (with the properties of ion selectivity and activation), and they succeed in accomplishing the same function with only a meager similarity in primary amino acid sequence.

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Metadata

Authors
Pinto, L. H., & Lamb, R. A.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
2006-04
Volume
281
Issue
14
Pages
8997-9000
ISSN
0021-9258 (ISSN-L)
OpenAlex
W2155734592
Cited by
459
References
0
FWCI
6.33
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: The M2 Proton Channels of Influenza A and B Viruses. https://app.cochat.ai/papers/10.1074/jbc.r500020200
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Pinto, L. H., & Lamb, R. A. (2006). The M2 Proton Channels of Influenza A and B Viruses. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.r500020200

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.