Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation

Cited by (248)

Items 201–248 of 248

  1. Animal Models and Ethics in the Testing of Drugs for Alzheimer’s Disease
    Parikshit Roychowdhury, Antony Justin, Mirunalini Gobinath, Veera Venkata Satyanarayana Reddy Karri, Gowthamarajan Kuppusamy · 2024 · Springer eBooks
  2. Exploring sex-specific alterations in early Alzheimer’s disease using network MRI analyses
    Ines Ben Abdallah, Marion Sourty, Marion Rame, Laëtitia Degiorgis, Aminé Isik, Chantal Mathis, Laura Adela Harsan · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  3. Reviewer #2 (Public review): Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer’s disease
    2025 · eLife
  4. Author response: Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer’s disease
    Vibhavari Aysha Bansal, Jia Min Tan, Hui Rong Soon, Norliyana Zainolabidin, Takaomi C. Saido, Toh Hean Ch’ng · 2025 · eLife
  5. Reviewer #2 (Public review): Misclassification in memory modification in AppNL-G-F knock-in mouse model of Alzheimer’s disease
    2025 · eLife
  6. Misclassification in memory modification in AppNL-G-F knock-in mouse model of Alzheimer’s disease
    Mei-Lun Huang, Yusuke Suzuki, Hiroki Sasaguri, Takashi Saito, Takaomi C. Saido, Itaru Imayoshi · 2025 · eLife
  7. Misclassification in memory modification in AppNL-G-F knock-in mouse model of Alzheimer’s disease
    Mei-Lun Huang, Yusuke Suzuki, Hiroki Sasaguri, Takashi Saito, Takaomi C. Saido, Itaru Imayoshi · 2025 · eLife
  8. Amyloid- and Tau-Targeted Therapies in Alzheimer’s Disease
    Alexander J. Rajic, Douglas R Galasko, Mark H. Tuszynski · 2025 · Springer eBooks
  9. BAG3 in traumatic brain injury: A cell-type-specific modulator of tau hyperphosphorylation
    Nicholas Sweeney, Tae Yeon Kim, Hongjun Fu · 2025 · Neural Regeneration Research
  10. Stem Cell-Derived 3D Models to Study Alzheimer’s Disease
    José Inzunza, Aphrodite Demetriou, Patricia Muñoz, Jonathan Arias, Ivan Nalvarte · 2025 · Stem cell biology and regenerative medicine
  11. Additional file 3 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia
    Diana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
  12. Additional file 12 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Li, Hao, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Gobom, Johan et al. · 2022 · Figshare
  13. Additional file 1 of Hsp90 co-chaperones, FKBP52 and Aha1, promote tau pathogenesis in aged wild-type mice
    Marangelie Criado‐Marrero, Niat T. Gebru, Danielle M. Blazier, Lauren A. Gould, Jeremy D. Baker, David Beaulieu‐Abdelahad, Laura J. Blair · 2021 · Figshare
  14. Additional file 5 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia
    Diana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
  15. Additional file 2 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia
    Diana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
  16. Additional file 11 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Li, Hao, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Gobom, Johan et al. · 2022 · Figshare
  17. Additional file 10 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Li, Hao, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Gobom, Johan et al. · 2022 · Figshare
  18. Additional file 6 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia
    Diana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
  19. Additional file 4 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Li, Hao, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Gobom, Johan et al. · 2022 · Figshare
  20. Additional file 4 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia
    Diana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
  21. Additional file 9 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Li, Hao, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Gobom, Johan et al. · 2022 · Figshare
  22. Additional file 1 of Torpor induces reversible tau hyperphosphorylation and accumulation in mice expressing human tau
    Christina F. de Veij Mestdagh, Witte, M. E., Wiep Scheper, A.B. Smit, Henning, R. H., Ronald E. van Kesteren · 2024 · Figshare
  23. Additional file 1 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microglia
    Diana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
  24. Additional file 3 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Li, Hao, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Gobom, Johan et al. · 2022 · Figshare
  25. Additional file 6 of Increased CSF-decorin predicts brain pathological changes driven by Alzheimer’s Aβ amyloidosis
    Richeng Jiang, Una Smailović, Hazal Haytural, Betty Marije Tijms, Li, Hao, Robert Mihai Haret, Ganna Shevchenko, Gefei Chen, Axel Abelein, Gobom, Johan et al. · 2022 · Figshare
  26. Mouse models of Alzheimer’s disease pathology
    Sunwoo Kim, Nora E. Gray · 2025 · Elsevier eBooks
  27. A critical appraisal of the link between apolipoprotein E and Tau
    Sudeshna Das, Bradley T. Hyman, Alberto Serrano‐Pozo · 2026 · Current Opinion in Neurology
  28. Humanized tau and amyloid-β deposition accelerate tau propagation, neuronal cell loss and neurophysiological dysfunction in novel mouse models of primary age-related tauopathy and Alzheimer’s disease
    Arun Reddy Ravula, Ayaka Hagita-Tatsumoto, Brendan J. Gibbs, Nibedita Basu Ray, J. W Ellison, Alejandro Longtree‐Preciado, Stephanie Radhakishun, Wenhui Qiao, Na Zhao, Takashi Saito et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  29. Propagation axonale des pathologies Tau et Aβ dans la maladie d'Alzheimer : à la recherche de propagons dans le circuit subiculo-fornico-mamillaire
    Manon Thierry · 2020 · theses.fr (ABES)
  30. Étude du rôle de la microglie dans la propagation de la protéine Tau : mise en place de nouveaux modèles
    Charlotte Duwat · 2021 · theses.fr (ABES)
  31. The Use of Localized Proteomics to Understand the Pathogenesis of Alzheimer's Disease
    Geoffrey Pires · 2021 · theses.fr (ABES)
  32. Étude de la forme sporadique de la maladie d'Alzheimer à partir de modèles in vivo et de neurones humains reprogrammés
    Camille Thiberge · 2023 · theses.fr (ABES)
  33. Using β-strand and β-hairpin peptidomimetics induced by constrained amino acids to modulate the aggregation of the microtubule associated protein Tau : design, synthesis and evaluation
    Davide Di Lorenzo · 2023 · theses.fr (ABES)
  34. Etude des mécanismes physiοpathοlοgiques de la maladie d'Alzheimer : appοrt de l'étude des variants du gène SΟRL1
    Romain Castelot · 2024 · theses.fr (ABES)
  35. Caractérisation et modulation du microbiote intestinal dans le contexte de la maladie d’Alzheimer : vers une nouvelle piste thérapeutique
    Caroline Ismeurt · 2021 · theses.fr (ABES)
  36. The Role of Tubulin Polyglutamylation in Controlling the Binding and Activity of Microtubule-Interacting Proteins
    Mariya Genova · 2023 · theses.fr (ABES)
  37. The light at the end of the tunnel : study of early-stage brain dynamics alterations in Alzheimer’s disease and beneficial effects of light stimulation in the AppNL-F/MAPT mouse model
    Matthieu Aguilera · 2024 · theses.fr (ABES)
  38. Vertebrate Animal Models of Primary 4-Repeat Tauopathies
    Denglei Ma, Edward A. Burton · 2026 · Contemporary clinical neuroscience
  39. Amyloid beta exacerbates Tau-seeded pathology and drives tangle formation in human neuronal xenografts
    Bart De Strooper, Jacqueline F. M. van Vierbergen, Sriram Balusu, Katrien Horré, Nóra Baligács, Dries T'svyen, Iordana Chrysidou, Annerieke S. R. Sierksma, Lutgarde Serneels, Dietmar Rudolf Thal et al. · 2026 · Research Square
  40. Robust tauopathy and memory deficits in a mouse model constitutively overexpressing human P301L MAPT
    Matthew J. Hamm, Kevin McNaught, Christopher Janus, Emely A. Gazarov, Zachary Strickland, Jessica Shubin, Jessica Reinhardt, Jinho Park, Sruti Rayaprolu, William V. Antropov et al. · 2026 · Neurobiology of Disease
  41. Amyloid exacerbates tau and alpha‐synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model
    Benjamin E. Rabichow, Lacey Nixon, Lauren Tallant, Katelin A. Gibson, David G. Nascari, J. Hudson Barnett, Nashali Massa, John Denis Fryer · 2026 · Alzheimer s & Dementia
  42. Tau Isoform Expression Drives Disease Outcomes Following a Single Closed Head Injury
    Rachel Furhang, Riley Morrone, Elena Nikulina, Mahdavi Jere, Ashmeet Kaur, Fizza Nayab, Takashi Saito, Takaomi C. Saido, Peter John Bergold · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  43. Retinal manifestations of Alzheimer's Disease: Insights from animal models, clinical detection, and future translation
    Xiayin Zhang, Dongli Zhuang, Chunran Lai, Chunwen Zheng, Zhi Da Soh, Siegfried K. Wagner, Vera Yuan Cai, Zhongwei Yang, Shan Wang, Xingchen Geng et al. · 2026 · Progress in Retinal and Eye Research
  44. Are mouse models of Alzheimer’s disease truly flawed, or are we misusing them?
    Frédéric Calon, Léa Otaegui, Mohamed Lala Bouali, Sébastien S. Hébert · 2026 · Neuroscience
  45. Tau isoforms modulate the axon initial segment controlling axonal trafficking and neuronal excitability
    Cayetana Arnaiz, Gonzalo Escalante, Lautaro Rodriguez Donghi, Mariana Inés Holubiec, Olivia Pedroncini, Indiana Páez Paz, Clara Gaguine, Julieta Bianchelli, Jordi Navarro, Micaela D. García et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  46. Effect of tau silencing on tau pathology propagation, a treatment efficient at the earliest stages of the disease?
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  47. Gene therapy in Alzheimer’s disease (AD)
    Maryam Bemanalizadeh, Mitra Ashrafi, Mahdieh Eslami, Shiva Moein, Asad Kazemi, Vahid Mansouri · 2026 · Elsevier eBooks
  48. Protein Quality Control Systems in Neurodegeneration—Chaperones, Cytoskeleton, and the Pathogenic Transition of Tau
    Anjali Bisht, Srikanth Pippadpally, Vimlesh Kumar · 2026 · Molecular Neurobiology