Nutrition and maternal morbidity and mortality
Open accessAbstract
Nearly 600 000 women die every year from pregnancy related conditions and the maternal mortality rates (MMR = deaths per 100 000 live births) in developing countries may be as high as 1000 compared with less than ten in industrialised countries. In the light of the striking impact of deficiencies of micronutrients such as vitamin A and zinc on immune function, morbidity and mortality in children it seems reasonable to suggest that such deficiencies might play a contributing role in the high rates of morbidity and mortality in mothers. Hitherto, there has been rather little published on the contribution of malnutrition to maternal morbidity or mortality but recent results of micronutrient supplementation show a major effect of vitamin A or beta carotene supplementation on maternal mortality in Nepal and an impressive effect of a multiple micronutrient mixture on pregnancy outcome in Tanzania. There is now data showing that subclinical mastitis, a potential risk factor for mother to child transmission of HIV by increasing levels of virus in breast milk, is influenced by maternal diet in Tanzania and feeding patterns in South Africa. Considering the massive tragedy of maternal mortality the recent data provides opportunities for new, innovative nutritional interventions for the reduction of the global burden of maternal morbidity and mortality.
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Historical studies do not isolate the effect of Sweden's midwifery policies from other potentially important influences, such as the introduction of antiseptic technology and changes in nutrition.
“However, these studies do not isolate the effect of Sweden's midwifery policies from other potentially important influences, such as the introduction of antiseptic technology and changes in nutrition (Högberg, Wall, and Broströmc 1986; Tomkins 2001).”
From Occupational Licensing and Maternal Health: Evidence from Early Midwifery Laws (2020) · cites this paper as Tomkins 2001
The “Measurement issues and trends” section (page not provided) says historical analyses of maternal mortality in the UK were limited and describes several concurrent changes in obstetric care. This supports the general concern about separating influences, but the paper does not assess Sweden’s midwifery policies or identify antiseptic technology as a concurrent influence. (LLM, conf=0.82)
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“In Nepal also, it was established that there was a 44% reduction in maternal mortality because of this vitamin supplementation programme (Tomkins 2001).”
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“Maternal mortality rates are calculated as death per 100,000 births, extending from 28 weeks of pregnancy to 6 weeks postpartum (Tomkins, 2001).”
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“It has been suggested that improved antioxidant intake may reduce maternal morbidity (Tomkins, 2001).”
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- Authors
- Tomkins, A.
- Affiliations
- University College London (GB)
- Corresponding author
- Tomkins, Andrew
- ORCID
- Tomkins, Andrew
- Venue
- British Journal of Nutrition
- Publisher
- Cambridge University Press (CUP)
- Published
- 2001-05
- Volume
- 85
- Issue
- S2
- Pages
- S93-S99
- ISSN
- 0007-1145 (ISSN-L)
- 1475-2662
- OpenAlex
- W2047037904
- Cited by
- 61
- References
- 86
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 3 · 2021: 2 · 2020: 1 · 2018: 2 · 2017: 1 · 2016: 2 · 2014: 4 · 2013: 1 · 2012: 3
- FWCI
- 0.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- British Journal Of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- ePrints Soton (University of Southampton) (submittedVersion)
- Funders
- Wellcome Trust
- Department for International Development
- Great Ormond Street Hospital for Children
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Child Nutrition and Water Access
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Global Maternal and Child Health
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Public Health and Nutrition
- Keywords
- maternal mortality, maternal morbidity, micronutrient deficiency, vitamin A supplementation, beta-carotene, multiple micronutrient supplementation, subclinical mastitis, mother-to-child HIV transmission, maternal diet, pregnancy outcomes, malnutrition, immune function
- MeSH terms
- Adolescent, Adult, Breath Tests, Energy Intake, Carbon Dioxide, Carbon Isotopes, Child, Child Nutritional Physiological Phenomena, Dietary Fats, Digestion, Digestive System, Feces, Female, Follow-Up Studies, Glycocholic Acid, Humans, Male, Nutrition Disorders, Respiration, Triglycerides, Weight Gain
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