Successful non-surgical treatment of Candida tropicalis endocarditis with liposomal amphotericin-B (AmBisome
Abstract
Fungal endocarditis in children is most commonly a complication of palliative or curative surgery for congenital heart disease, rheumatic valvulitis and prolonged indwelling central venous and umbilical catheters. We describe here the case of a 3-y-old patient with chronic diarrhoea and prolonged total parenteral alimentation who developed severe C. tropicalis endocarditis and was treated successfully using a liposomal preparation of amphotericin-B (AmBisome) without surgical intervention.
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Successful primary therapy with fluconazole and liposomal amphotericin B has been described for patients with native valve Candida endocarditis.
“Successful primary therapy with fluconazole [105] and liposomal amphotericin B [230] has been described for patients with native valve infections.”
From Guidelines for Treatment of Candidiasis (2004) · cites this paper as [230]
Cites
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- Authors
- Rimma Melamed, E. L.
- Venue
- Scandinavian Journal of Infectious Diseases
- Publisher
- Informa UK Limited
- Published
- 2000-01
- Volume
- 32
- Issue
- 1
- Pages
- 86-89
- ISSN
- 0036-5548 (ISSN-L)
- 1651-1980
- OpenAlex
- W2167392143
- Cited by
- 32
- References
- 11
- Citations by year
- 2024: 1 · 2022: 1 · 2021: 1 · 2018: 1 · 2017: 1 · 2015: 1 · 2014: 1 · 2013: 3 · 2012: 4
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Scandinavian Journal of Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Ophthalmology › Ocular Infections and Treatments
- Keywords
- Candida tropicalis, fungal endocarditis, liposomal amphotericin B, conservative treatment, pediatric patients, total parenteral nutrition, chronic diarrhea, central venous catheters, congenital heart disease
- MeSH terms
- Amphotericin B, Antifungal Agents, Candida, Candidiasis, Child, Preschool, Chronic Disease, Diarrhea, Drug Carriers, Echocardiography, Endocarditis, Heart Atria, Humans, Liposomes, Male, Treatment Outcome
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