Epidural analgesia associations with depression, PTSD, and bonding at 2 months postpartum
Abstract
The research aim was to study the possible effect of epidural analgesia, as well as other possible demographic/obstetric variables and subjective birth experience on postpartum depression, PTSD, and impaired bonding. This was a longitudinal study of 254 women who gave birth at the maternity wards of a large tertiary health center and responded to questionnaires at T1 (Childbirth Experience Questionnaire and level of fatigue question; in person, 1-4 days postpartum) and at T2 (Postnatal Depression Scale, Postpartum Bonding Questionnaire, and the City Birth Trauma Scale; online-two months postpartum). Obstetric and demographic data were taken from medical files. Having a previous psychiatric diagnosis and higher levels of fatigue significantly predicted worse outcomes in all measures (level of fatigue was not associated with the City Birth Trauma birth-related symptoms factor). Having higher education, being primiparous, worse birth experience, and longer second stage of birth predicted worse outcomes in some measures. Although epidural administration had no effect on any of the outcome variables, special attention should be devoted to women who had long second-stage births and/or suffering from postpartum fatigue to prevent postpartum psychopathology. In addition, demographic variables, such as primiparity, education, and prior psychopathology diagnosis should be considered to treat women and prevent postpartum psychopathology.
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Prolonged second-stage births and postpartum fatigue are associated with increased risk of postpartum psychopathology.
“Special attention should also be devoted to women who experience prolonged second-stage births and/or suffer from postpartum fatigue, as both are associated with increased risk of postpartum psychopathology.83”
Primiparity, education, and prior psychological diagnosis are factors associated with postpartum psychopathology.
“Additional factors such as primiparity, education, and prior psychological diagnosis should be considered to guide preventive efforts against postpartum psychopathology.83”
Cites
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Postpartum fatigue and depression: A systematic review and meta-analysis
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Fagan, J., Dufour, S., Duet, S., Downs, E., Siddaiah, H., Viswanath, O., Shekoohi, S., & Kaye, A. (2026) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s579920
- Authors
- Handelzalts, J. E., Levy, S., Krissi, H., & Peled, Y.
- Affiliations
- University of Michigan (US)
- Academic College of Tel Aviv-Yafo (IL)
- Tel Aviv University (IL)
- Corresponding author
- Handelzalts, Jonathan E.
- Venue
- Journal of Psychosomatic Obstetrics & Gynecology
- Publisher
- Informa UK Limited
- Published
- 2022-06-28
- Volume
- 43
- Issue
- 4
- Pages
- 488-494
- ISSN
- 0167-482X (ISSN-L)
- 1743-8942
- OpenAlex
- W4283643531
- Cited by
- 7
- References
- 5
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 2
- FWCI
- 1.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Obstetrics & Gynecology (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Health Sciences › Medicine › Surgery › Anesthesia and Pain Management
- Keywords
- epidural analgesia, postpartum depression, post-traumatic stress disorder, postpartum bonding, childbirth experience, birth trauma, postpartum fatigue, primiparity, educational attainment, second stage of labor, obstetric factors
- MeSH terms
- Depression, Female, Humans, Longitudinal Studies, Pregnancy, Surveys and Questionnaires, Stress Disorders, Post-Traumatic, Analgesia, Epidural, Depression, Postpartum, Postpartum Period
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