A review of mild head trauma. Part I: Meta-analytic review of neuropsychological studies.
Abstract
We conducted a meta-analytic review of neuropsychological studies of mild head trauma (MHT). Studies were included if they met these criteria: patients studied at least 3 months after MHT; patients selected because of a history of MHT rather than because they were symptomatic; and attrition rate of less than 50% for longitudinal studies. Studies of children were not considered. We found a total of 8 published papers with 11 samples that met these criteria. Using the g statistics, the overall effect size of 0.07 was nonsignificant, but the d statistic yielded an effect size of 0.12, p < .03. Measurers of attention had the largest effect, g = 0.17. p < .02 and d = 0.20, p < .006. Severity of injury accounted for far more variance than did specific neuropsychological domain, however. The small effect size suggests that the maximum prevalence of persistent neuropsychological deficit is likely to be small and neuropsychological assessment is likely to have positive predictive value of less than 50%. Consequently, clinicians will more likely be correct when not diagnosing brain injury than when diagnosing a brain injury in cases with chronic disability after MHT.
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These findings align with prior studies and provide some of the strongest evidence to date that in unselected mTBI cases, lower cognitive performance does not chronically persist relative to controls.
“These findings align with prior studies and provide some of the strongest evidence to date that in unselected mTBI cases, lower cognitive performance does not chronically persist relative to controls (Belanger et al., 2005; Binder et al., 1997; Frencham et al., 2005; Karr et al., 2014; Rohling et al., 2011; Schretlen & Shapiro, 2003).”
From Can mild traumatic brain injury alter cognition chronically? A LIMBIC-CENC multicenter study. (2023) · cites this paper as Binder et al., 1997
Objective, late cognitive deficits after mTBI have been elusive to document at the group level, with multiple meta-analytic reviews concluding insufficient evidence for deleterious effects of mTBI on objective cognitive assessment beyond the first few months post-injury.
“In general, objective, late cognitive deficits after mTBI have been elusive to document at the group level, with multiple, meta-analytic reviews concluding insufficient evidence for deleterious effects of mTBI on objective cognitive assessment beyond the first few months post-injury”
From Can mild traumatic brain injury alter cognition chronically? A LIMBIC-CENC multicenter study. (2023) · cites this paper as Binder et al., 1997
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References 39 · Cited by 502
- Authors
- Binder, L. M., Rohling, M. L., & Larrabee, G. J.
- Affiliations
- Oregon Health & Science University (US)
- University of Nebraska–Lincoln (US)
- ORCID
- Rohling, Martin L.
- Venue
- Journal of Clinical and Experimental Neuropsychology
- Publisher
- Informa UK Limited
- Published
- 1997-06
- Volume
- 19
- Issue
- 3
- Pages
- 421-431
- ISSN
- 0165-0475 (ISSN-L)
- 1380-3395
- 1744-411X
- OpenAlex
- W2095792933
- Cited by
- 502
- References
- 39
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 5 · 2023: 5 · 2022: 6 · 2021: 12 · 2020: 13 · 2019: 26 · 2018: 16 · 2017: 13 · 2016: 23 · 2015: 21 · 2014: 34 · 2013: 32 · 2012: 25
- FWCI
- 9.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical and Experimental Neuropsychology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
- Keywords
- mild traumatic brain injury, concussion, attention deficits, injury severity, effect size, positive predictive value, chronic disability, brain injury diagnosis
- MeSH terms
- Clinical Trials as Topic, Craniocerebral Trauma, Humans, Neuropsychological Tests, Predictive Value of Tests
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