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The psychoneuroimmunology of pregnancy
Abstract
This review develops the hypothesis that psychosocial stress during the prenatal period has negative effects on pregnancy and birth outcome via altering maternal immune function. Clinical literature addressing the role of prenatal stress in pregnancy and infant outcome, immunity and infection during pregnancy, and the impact of stress on health in non-pregnant adults is synthesized to support a model of the psychoneuroimmunology of pregnancy in which stress-induced immunosuppression in pregnancy contributes to pregnancy complications and suboptimal infant development. Possible mechanisms for the impact of stress on pregnancy and birth are discussed as well as suggested avenues for exploration of these connections.
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“Since that time, several studies have supported these conclusions (see Coussons-Reide, Okun, and Simms 2003 for a review of such studies).”
From Resistance and Resilience: The Sojourner Syndrome and the Social Context of Reproduction in Cenral Harlem (2005) · cites this paper as Coussons-Reide, Okun, and Simms 2003
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Schetter, C. D. (2010) · Annual Review of Psychology · doi:10.1146/annurev.psych.031809.130727 · Cited by 977
Psychosocial stress increases inflammatory markers and alters cytokine production across pregnancy
Coussons-Read, M. E., Okun, M. L., & Nettles, C. D. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2006.08.006 · Cited by 459
Self-citationPrenatal Stress Alters Cytokine Levels in a Manner That May Endanger Human Pregnancy
Coussons‐Read, M. E., Okun, M. L., Schmitt, M. P., & Giese, S. (2005) · Psychosomatic Medicine · doi:10.1097/01.psy.0000170331.74960.ad · Cited by 252
Self-citationMullings, L. (2005) · Transforming Anthropology · doi:10.1525/tran.2005.13.2.79 · Cited by 216
Effects of integrated yoga on quality of life and interpersonal relationship of pregnant women
Rakhshani, A., Maharana, S., Nagarathna, R., Nagendra, H. R., & Padmalatha, V. (2010) · Quality of Life Research · doi:10.1007/s11136-010-9709-2 · Cited by 95
Metadata
- Authors
- Coussons-Read, M., Okun, M., & Simms, S.
- Affiliations
- University of Colorado Denver (US)
- Venue
- Journal of Reproductive and Infant Psychology
- Publisher
- Informa UK Limited
- Published
- 2003-05
- Volume
- 21
- Issue
- 2
- Pages
- 103-112
- ISSN
- 0264-6838 (ISSN-L)
- 1469-672X
- OpenAlex
- W1977591750
- Cited by
- 22
- References
- 0
- Citations by year
- 2023: 1 · 2022: 2 · 2021: 1 · 2019: 1 · 2018: 2 · 2016: 1 · 2014: 3
- FWCI
- 1.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Reproductive and Infant Psychology (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Keywords
- psychoneuroimmunology, pregnancy, prenatal stress, maternal immune function, immunosuppression, pregnancy complications, birth outcomes, infant development, infection during pregnancy
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Cite CoChat for the checks on this page, and the paper for its own findings.
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- CoChat. (2026). Citation check: The psychoneuroimmunology of pregnancy. https://app.cochat.ai/papers/10.1080/0264683031000124064
- The paper
- Coussons-Read, M., Okun, M., & Simms, S. (2003). The psychoneuroimmunology of pregnancy. Journal of Reproductive and Infant Psychology. https://doi.org/10.1080/0264683031000124064
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.