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Surface engineered bimetallic nanoparticles based therapeutic and imaging platform: Recent advancements and future perspective
Abstract
The unique physical and chemical properties of monometallic nanoparticles have been comprehensively explored. Analogously, the combination of two metals induces alterations in the system's electron density, termed as Bimetallic nanoparticles (BMNP's) were found to be more desirable than monometallic nanoparticles due to improved stability, activity, and selectivity, thus altering the chemical, optical, and electrical properties. In this review, we showcase the importance in the context of biomedical applications. The article sheds light on utilising BMNP's in the field of theranostics, diagnosis, and therapeutics by focusing on anticancer, antimicrobial and wound healing activity along with the toxicological problems associated with BMNP's. In conclusion, BMNP's can be used as a novel therapeutic and diagnostic system to tackle major health concerns. GRAPHICAL ABSTRACT
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“Based on a previous study, alloy NPs have improved thermophysical properties compared to single-metal NPs [186].”
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Porter, N. S., Wu, H., Quan, Z., & Fang, J. (2013) · Accounts of Chemical Research · doi:10.1021/ar3002238 · Cited by 393
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Cited by
Sorted by citations
Subhan, A., Mourad, A.-H. I., & Al-Douri, Y. (2022) · Nanomaterials · doi:10.3390/nano12132144 · Cited by 95
“Based on a previous study, alloy NPs have improved thermophysical properties compared to single-metal NPs [186].”
Background
Metadata
- Authors
- Kotha, R., Fernandes, G., Nikam, A. N., Kulkarni, S., Pandey, A., Pandey, S., & Mutalik, S.
- Affiliations
- Manipal Academy of Higher Education (IN)
- University of the West Indies (TT)
- Corresponding author
- Mutalik, Srinivas
- Venue
- Materials Science and Technology
- Publisher
- SAGE Publications
- Published
- 2020-11
- Volume
- 36
- Issue
- 16
- Pages
- 1729-1748
- ISSN
- 0267-0836 (ISSN-L)
- 1743-2847
- OpenAlex
- W3093984286
- Cited by
- 17
- References
- 2
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 2 · 2022: 6 · 2021: 4
- FWCI
- 0.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Materials Science and Technology (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Physical Sciences › Materials Science › Materials Chemistry › Nanoparticles: synthesis and applications
- Physical Sciences › Materials Science › Electronic, Optical and Magnetic Materials › Gold and Silver Nanoparticles Synthesis and Applications
- Keywords
- bimetallic nanoparticles, surface engineering, theranostics, cancer therapy, antimicrobial activity, wound healing, nanoparticle toxicity, biomedical applications
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