The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Epidemiology and predictors of post-concussive syndrome after minor head injury in an emergency population
Abstract
OBJECTIVE: To determine if clinical variables or neurobehavioural test (NBT) scores obtained in the ED within 24 hours of minor head injury (MHI) predict the development of postconcussive syndrome (PCS). METHODS: Prospective, observational study of 71 MHI patients and 60 orthopaedic controls. MHI defined as loss of consciousness < 10 minutes or amnesia, GCS 15, no skull fracture or new neurologic focality on PE, and no brain injury on CT (if done). All patients received a seven part NBT battery in the ED. Telephone follow-up was done at 1, 3 and 6 months to determine if patients met the DSM IV definition of PCS. ANALYSIS: Stepwise, multivariate, logistic regression. RESULTS: Predictors of PCS at 1 month were female gender (OR = 7.8; 95% CI = 41.6, 1.98), presence of both retrograde and anterograde amnesia (OR = 0.055; CI = 0.002, 0.47), Digit Span Forward Scores (OR = 0.748; CI = 0.52, 1.03) and Hopkins Verbal Learning A scores (OR = 0.786; CI = 0.65, 0.91); at 3 months, presence of both retrograde and anterograde amnesia (OR = 0.13; CI = 0.0, 0.93), Digit Span Forward Scores (OR = 0.744; CI = 0.58, 0.94). No variables fit the model at 6 months. 92% of males scoring > 25 on Hopkins Verbal Learning A did not have PCS at 1 month, and 89% of females scoring < 9 on Digit Span Forward did have PCS at 1 month. CONCLUSIONS: Gender and two NBTs can help predict PCS after MHI.
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“Most human studies of mild TBI report that women experience a greater number, severity, and/or duration of post-concussive symptoms, such as headaches, fatigue, sleep disturbances, dizziness, irritability, aggressiveness, anxiousness, depression, work or relationship troubles, or short-term memory impairment. 52”
From Sex Differences in Traumatic Brain Injury: What We Know and What We Should Know (2019) · cites this paper as [52]
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Metadata
- Authors
- BAZARIAN, J. J., WONG, T., HARRIS, M., LEAHEY, N., MOOKERJEE, S., & DOMBOVY, M.
- Affiliations
- University of Rochester Medicine (US)
- ORCID
- BAZARIAN, JEFFREY J.
- Venue
- Brain Injury
- Publisher
- Informa UK Limited
- Published
- 1999-01
- Volume
- 13
- Issue
- 3
- Pages
- 173-189
- ISSN
- 0269-9052 (ISSN-L)
- 1362-301X
- OpenAlex
- W2068260202
- Cited by
- 332
- References
- 33
- Citations by year
- 2026: 3 · 2025: 11 · 2024: 12 · 2023: 7 · 2022: 7 · 2021: 10 · 2020: 18 · 2019: 23 · 2018: 11 · 2017: 8 · 2016: 13 · 2015: 18 · 2014: 22 · 2013: 16 · 2012: 20
- FWCI
- 3.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Brain Injury (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury and Neurovascular Disturbances
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Keywords
- post-concussion syndrome, mild traumatic brain injury, concussion, amnesia, digit span, verbal learning, gender differences, prognostic factors, emergency department
- MeSH terms
- Adult, Amnesia, Retrograde, Brain Concussion, Cognition Disorders, Emergencies, Female, Follow-Up Studies, Humans, Male, Neuropsychological Tests, Predictive Value of Tests, Prospective Studies, Sex Factors, Syndrome, Glasgow Coma Scale, Injury Severity Score
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Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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