Systematic review of the impact of demographic and socioeconomic factors on quality of life in ostomized colorectal cancer survivors
Open accessAbstract
Background: Formation of a fecal stoma may be necessary to ensure radical resection in colorectal cancer (CRC) patients but will substantially impact the health-related quality of life (HRQoL) in about 20% of cases. Little is known about patient-related risk factors for reduced HRQoL in patients with a permanent stoma. We, therefore, reviewed the current literature on how demographic and socioeconomic factors affect HRQoL in CRC survivors with a stoma.Material and methods: The databases Pubmed, Embase, CINAHL, and PsycINFO were systematically searched. Two independent reviewers extracted and quality-assessed eligible publications. Studies assessing HRQoL using a validated questionnaire at least 6 months after surgery for CRC were included if data on the impact of demographic and/or socioeconomic, factors on HRQoL were analyzed and presented.Results: Eligible studies predominantly presented small cross-sectional cohorts. Age showed equivocal results; hence, some studies found younger patients had inferior HRQoL compared with older patients, and others found no difference. Subdivision into age groups differed widely. Several studies found that both generic and stoma-specific HRQoL was lower in females compared with males. Most studies found that socioeconomic factors did not affect HRQoL while one study found lower education correlated to reduced HRQoL. Categorization of these factors also varied widely.Conclusions: This is to our knowledge the first systematic review on the impact of patient-related factors on HRQoL in long-term CRC survivors. We found that a stoma had more impact in younger ostomates than older and that HRQoL in females was reduced more than in males. Conclusions regarding other factors were difficult due to few studies and contradictory results. Further research in this subject is much needed in order to target preventive measures when planning surgery in patients in high risk of reduced HRQoL.
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Son et al. reportaron que, para la mayoría de los estudios, el efecto de las intervenciones psicosociales sobre la CdV no resultó ser estadísticamente significativo.
“Son et al. (23) realizaron un meta-análisis con el objetivo de identificar la efectividad de las intervenciones psicosociales sobre la CdV en pacientes con CCR, reportando que, para la mayoría de los estudios, el efecto de las intervenciones psicosociales sobre la CdV no resultó ser estadísticamente significativo”
From Efecto de intervenciones psicológicas sobre variables psicosociales en pacientes con cáncer colorrectal: una revisión narrativa de la literatura. (2022) · cites this paper as [23]
The cited paper’s Material and methods section explicitly says that variation among the included studies made a meta-analysis impossible, contrary to the citing sentence’s description of it as a meta-analysis. Its Results and Discussion concern demographic and socioeconomic factors in ostomized colorectal cancer survivors, not the effectiveness of psychosocial interventions; the claimed finding about statistical significance is not reported. (LLM, conf=0.89)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measuredSon et al. detectaron leves mejoras en la CdV en todos los grupos de intervención.
“sin embargo, se detectaron leves mejoras en la CdV en todos los grupos de intervención.”
From Efecto de intervenciones psicológicas sobre variables psicosociales en pacientes con cáncer colorrectal: una revisión narrativa de la literatura. (2022) · cites this paper as [23]
The Results (page unavailable) describe studies of demographic and socioeconomic factors affecting quality of life in ostomized colorectal cancer survivors, not improvements across intervention groups. Searches for Son and for quality-of-life improvements in intervention groups found no passage addressing the claimed finding. (LLM, conf=0.75)
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- Authors
- Kristensen, H. Ø., Thyø, A., & Christensen, P.
- Affiliations
- Aarhus University Hospital (DK)
- Corresponding author
- Kristensen, Helle Ø
- Venue
- Acta Oncologica
- Published
- 2019-01-30
- Volume
- 58
- Issue
- 5
- Pages
- 566-572
- ISSN
- 0284-186X (ISSN-L)
- 1651-226X
- OpenAlex
- W2914519264
- Cited by
- 23
- References
- 26
- Citations by year
- 2026: 7 · 2025: 1 · 2024: 5 · 2023: 3 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 1
- FWCI
- 0.36
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Acta Oncologica (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Stoma care and complications
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Health Sciences › Medicine › Oncology › Colorectal Cancer Surgical Treatments
- Keywords
- colorectal cancer, ostomy, health-related quality of life, colorectal cancer survivors, demographic factors, socioeconomic factors, age, sex differences, educational attainment, risk factors
- MeSH terms
- Cancer Survivors, Aged, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Ostomy, Quality of Life, Socioeconomic Factors, Colorectal Neoplasms
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