The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Curcumin as an Inhibitor of Cancer
Abstract
Curcumin I (Cur I) and curcumin III (Cur III) are the yellow coloring phenolic compounds isolated from the spice turmeric. The effect of curcumins on different stages of development of cancer was studied. Cur I inhibited benzopyrene- (BP) induced forestomach tumors in female Swiss mice, and Cur III inhibited dimethylbenzanthracene- (DMBA) induced skin tumors in Swiss bald mice. Cur I also inhibited DMBA-initiated, tetradeconyl phorbol acetate-promoted skin tumors in female Swiss mice. In vitro 3H-BP-DNA interaction studies, and in vivo carcinogen metabolizing enzyme studies revealed that curcumins exert anticarcinogenic activity by altering the activation and/or detoxification process of carcinogen metabolism. Cur I and Cur III also exhibit in vitro cytotoxicity against human chronic myeloid leukemia, which is dose dependent. This study shows that curcumins inhibit cancer at initiation, promotion and progression stages of development.
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Burton, K. (1956) · Biochemical Journal · doi:10.1042/bj0620315 · Cited by 14,090
The Carbon Monoxide-binding Pigment of Liver Microsomes
Omura, T., & Sato, R. (1964) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)82244-3 · Cited by 11,781
Cited by
CURCUMIN: THE INDIAN SOLID GOLD
Aggarwal, B. B., Sundaram, C., Malani, N., & Ichikawa, H. (2007) · ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY · doi:10.1007/978-0-387-46401-5_1 · Cited by 1,647
Surh, Y.-J. (1999) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/s1383-5742(99)00057-5 · Cited by 633
CURCUMIN‐DERIVED TRANSIENTS: A PULSED LASER AND PULSE RADIOLYSIS STUDY
Gorman, A. A., Hamblett, I., Srinivasan, V. S., & Wood, P. D. (1994) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1994.tb05053.x · Cited by 86
Metadata
- Authors
- Nagabhushan, M., & Bhide, S. V.
- Venue
- Journal of the American College of Nutrition
- Publisher
- Informa UK Limited
- Published
- 1992-04-01
- Volume
- 11
- Issue
- 2
- Pages
- 192-198
- ISSN
- 0731-5724 (ISSN-L)
- 1541-1087
- OpenAlex
- W2413775972
- Cited by
- 190
- References
- 2
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
