Impact of Nutritional Intervention on Length of Hospital Stay and Mortality among Hospitalized Patients with Malnutrition: A Clinical Randomized Controlled Trial
Abstract
Objective The objective of this study was to evaluate the impact of a nutritional intervention on hospital stay and mortality among hospitalized patients with malnutrition. Methods Hospitalized patients with a diagnosis of malnutrition were enrolled and randomly allocated to either an intervention or control group. Participants in the intervention group received an individualized nutrition plan according to energy and protein (1.0-1.5 g/kg) intake requirements as well as dietary advice based on face-to-face interviews with patients and their caregivers or family members. Individuals in the control group received standard nutritional management according to the Hospital Nutrition Department. Nutritional status and disease severity were assessed using nutritional risk screening. Length of hospital stay was defined by the number of days of hospitalization from hospital admission to medical discharge. Reference to another service or death were criteria for study withdrawal. To evaluate mortality, individuals were followed up for 6 months after hospital discharge. Hospital stay and mortality were the intention-to-treat analysis. Results A total of 55 patients with an average age of 57.1 ± 20.7 years were included into intervention (n = 28) and control (n = 27) groups, respectively. At basal condition, nutritional status, measured by nutritional risk screening score, was similar between the study groups (4.1 ± 0.8 vs 4.2 ± 1.2, p = 0.6). The average hospital stay was lower in the i…
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Eight studies investigate the effect of dietary enrichment.
“Eight studies investigate the effect of dietary enrichment [25-32].”
From ESPEN guideline on hospital nutrition (2021) · cites this paper as [32]
There is evidence of moderate to very low quality to suggest that supportive interventions to improve nutritional care result in minimal weight gain.
“there is evidence of moderate to very low 472 quality to suggest those supportive interventions to improve nutritional care result in minimal 473 weight gain [32].”
From ESPEN guideline on hospital nutrition (2021) · cites this paper as [32]
The recommended level for protein intake varies between studies but most studies referring to a recommendation are in the span between 1.0 and 1.5 g/kg BW/day.
“The recommended level for protein intake varies between 513 studies but most studies referring to a recommendation are in the span between 1.0 – 1.5 g/kg 514 BW/day [28, 29, 32, 36].”
From ESPEN guideline on hospital nutrition (2021) · cites this paper as [32]
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“Participants in the intervention group received an individualized nutrition plan according to energy (estimated by Mifflin’s predictive equation) [16] and protein (1.”
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ESPEN guideline on hospital nutrition
Thibault, R., Abbasoglu, O., Ioannou, E., Meija, L., Ottens-Oussoren, K., Pichard, C., Rothenberg, E., Rubin, D., Siljamäki-Ojansuu, U., Vaillant, M.-F., et al. (2021) · Clinical Nutrition · doi:10.1016/j.clnu.2021.09.039 · Cited by 259 · see citing works
- Authors
- Cano-Torres, E. A., Simental-Mendía, L. E., Morales-Garza, L. A., Ramos-Delgado, J. M., Reyes-Gonzalez, M. M., Sánchez-Nava, V. M., Barragán-Berlanga, A. D. J., Rangel-Rodríguez, I., & Guerrero-Romero, F.
- Affiliations
- Tecnológico de Monterrey (MX)
- Biomedical Research Unit of the Mexican Social Security Institute at Durango, Durango, Dgo., México
- Hospital San José, Escuela Nacional de Medicina del Tecnológico de Monterrey, Monterrey, Nuevo León, México
- Hospital Metropolitano Dr. Bernardo Sepúlveda, Secretaria de Salud de Nuevo León, Monterrey, Nuevo León, México
- Venue
- Journal of the American College of Nutrition
- Publisher
- Informa UK Limited
- Published
- 2017-03-20
- Volume
- 36
- Issue
- 4
- Pages
- 235-239
- ISSN
- 0731-5724 (ISSN-L)
- 1541-1087
- OpenAlex
- W2603709845
- Cited by
- 26
- References
- 3
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 9 · 2020: 1 · 2019: 2 · 2017: 1
- FWCI
- 0.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American College of Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Health Professions › Health Information Management › Dietetics, Nutrition, and Education
- Keywords
- malnutrition, dietary intervention, hospitalized patients, length of hospital stay, mortality, dietary recommendations, protein intake, energy requirements, nutritional risk screening, hospital discharge
- MeSH terms
- Adult, Aged, Diet, Female, Hospitalization, Humans, Inpatients, Length of Stay, Male, Middle Aged, Nutritional Status, Risk Factors, Malnutrition, Nutrition Therapy
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