CoChat
Sign Up
Cited by 15Personality Disorders and PsychopathologyAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesTreatment of Major Depression

Long-term outcome of patients with dysthymia and panic disorder: A naturalistic 9-year follow-up study

Svanborg, Cecilia, Wistedt, Anna Åberg, Svanborg, Pär·2008·Nordic Journal of Psychiatry
DOI 10.1080/08039480801960123
Open this paper in CoChat — free account

Abstract

The highly prevalent psychiatric disorders dysthymia and panic disorder have often a chronic or recurrent course with superimposed major depression. The prominent comorbidity between these diagnoses constitutes a confounding factor in the study of long-term outcome. We performed a 9-year follow-up of 38 patients with "pure" diagnoses, i.e. without comorbid dysthymia and panic disorder, selected from two 2-year naturalistic treatment studies with psychotherapy and antidepressant medication. The aims of the present study were to investigate 1) the stability of change, and 2) the impact of comorbid personality disorders (PDs) on long-term outcome. Patients were reassessed with SCID-I and SCID-II interviews, SCL-90/BSI and a detailed, modified life-charting interview, investigating course and treatment over time. About 50% of patients showed substantial improvement, of whom about half were in remission. Comorbid PD was a negative prognostic factor independently of Axis I diagnosis. Although patients with panic disorder had a lower frequency of comorbid PD, later onset, shorter duration of illness and better outcome after the original studies, there was no difference in the long-term outcome. The less stable outcome among panic patients suggests that standard treatments are not resulting in enduring remission. In order to achieve remission, it is necessary to 1) address comorbid PDs, 2) perform careful assessments of all comorbid diagnoses, and 3) build routines for the follow-up and augmentation of treatments.

Integrity signals

Registry

Crossref · 10.1080/08039480801960123

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Svanborg, C., Wistedt, A. Å., & Svanborg, P.
Affiliations
  • Karolinska Institutet (SE)
  • Karolinska University Hospital (SE)
Corresponding author
Svanborg, Cecilia
ORCID
Svanborg, Cecilia
Venue
Nordic Journal of Psychiatry
Publisher
Informa UK Limited
Published
2008-01
Volume
62
Issue
1
Pages
17-24
ISSN
  • 0029-1455 (ISSN-L)
  • 0803-9488
  • 1502-4725
DOI
10.1080/08039480801960123
OpenAlex
W2134424491
Cited by
15
References
37
Citations by year
2021: 2 · 2017: 2 · 2016: 2 · 2013: 2 · 2012: 2
FWCI
1.86
Type
journal article
Language
en
Open access
closed
Locations
  • Nordic Journal of Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
Eli Lilly and Company
Topics
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Keywords
dysthymia, panic disorder, long-term outcomes, personality disorders, comorbidities, remission, prognosis, major depressive disorder, psychotherapy, antidepressants
MeSH terms
Adult, Antidepressive Agents, Combined Modality Therapy, Female, Follow-Up Studies, Humans, Interview, Psychological, Male, Personality Disorders, Prognosis, Surveys and Questionnaires, Severity of Illness Index, Comorbidity, Cognitive Behavioral Therapy, Panic Disorder, Treatment Outcome, Selective Serotonin Reuptake Inhibitors, Dysthymic Disorder, Diagnostic and Statistical Manual of Mental Disorders

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review