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The Toxicological Response of Brazilian Chrysotile Asbestos: A Multidose Subchronic 90-Day Inhalation Toxicology Study with 92-Day Recovery to Assess Cellular and Pathological Response

Bernstein, David M., Rogers, Rick, Smith, Paul, Chevalier, Jörg·2006·Inhalation Toxicology
DOI 10.1080/08958370500515871
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Abstract

Inhalation toxicology studies with chrysotile asbestos have in the past been performed at exceedingly high doses without consideration of fiber number or dimensions. As such, the exposures have exceeded lung overload levels, making quantitative assessment of these studies difficult if not impossible. To assess the cellular and pathological response in the rat lung to a well-characterized aerosol of chrysotile asbestos, a 90-day subchronic inhalation toxicology study was performed using a commercial Brazilian chrysotile (CA 300). The protocol was based on that established by the European Commission for the evaluation of synthetic vitreous fibers. The study was also designed to assess the potential for reversibility of any such changes and to permit association of responses with fiber dose in the lung and the influence of fiber length. Wistar male rats were randomly assigned to an air control group and to 2 CA 300 exposure groups at mean fiber aerosol concentrations of 76 fibers L > 20 microm/cm3 (3413 total fibers/cm3; 536 WHO fibers/cm3) or 207 fibers L > 20 microm/cm3 (8941 total fibers/cm3; 1429 WHO fibers/cm3). The animals were exposed using a flow-past, nose-only exposure system for 5 days/wk, 6 h/day, during 13 consecutive weeks (65 exposures), followed by a subsequent nonexposure period lasting for 92 days. Animals were sacrificed after cessation of exposure and after 50 and 92 days of nonexposure recovery. At each sacrifice, subgroups of rats were assessed for the dete…

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Research works printed but not linked: 39

  1. Agency f or, 2003, Report on the Expert Panel on Health Effects of Asbestos and Synthetic Vitreous Fibers: The influence of fiber length
  2. Bellmann B., 1992, Environ. Health. Perspect., 97, 189, 10.1289/ehp.9297189 · DOI
  3. Bellmann B., 2003, Inhal. Toxicol., 15, 1147, 10.1080/08958370390229843 · DOI
  4. Berman D. W., 2003, Technical support document for a protocol to assess asbestos-related risk
  5. Bernstein D. M., 1999, Methods for the determination of the hazardous properties for human health of man made mineral fibers (MMMF)
  6. 10.1289/ehp.94102s515 · DOI · Paper page
  7. Bernstein D. M., 2001, Inhal. Toxicol., 13, 823, 10.1080/089583701752378133 · DOI
  8. Bernstein D. M., 2001, Inhal. Toxicol., 13, 851, 10.1080/089583701752378142 · DOI
  9. Bernstein D. M., 2003, Inhal. Toxicol., 15, 1387, 10.1080/08958370390248888 · DOI
  10. Bernstein D. M., 2004, Inhal. Toxicol., 16, 745, 10.1080/08958370490490176 · DOI · Paper page
  11. Bernstein D. M., 2005, Inhal. Toxicol., 17, 427, 10.1080/08958370591002012 · DOI · Paper page
  12. Bolton R. E., 1983, Br. J. Ind. Med, 40, 264
  13. Cannon W. C., 1983, Am. Ind. Hyg. Assoc. J., 44, 923, 10.1080/15298668391405959 · DOI
  14. Christensen V. R., 1994, Environ. Health Perspect., 102, 83, 10.1289/ehp.94102s583 · DOI
  15. Coin P. G., 1992, Environ. Res., 58, 97, 10.1016/S0013-9351(05)80207-5 · DOI · Paper page
  16. Cossette M., 1979, short course in mineralogical techniques of asbestos determination, 79
  17. Cruxên Barros de Oliveira M., 1989, Mineralogical analysis chrysotile
  18. 10.1089/089426802320282338 · DOI
  19. Gilmour P. S., 2004, Toxicol. Appl. Pharmacol., 195, 35, 10.1016/j.taap.2003.10.003 · DOI
  20. Hesterberg T. W., 1993, Fundam. Appl. Toxicol., 20, 464, 10.1006/faat.1993.1057 · DOI · Paper page
  21. Hesterberg T. W., 1998, Toxicol. Appl. Pharmacol., 151, 262, 10.1006/taap.1998.8472 · DOI · Paper page
  22. Hext P. M, 1994, Hum. Exp. Toxicol., 13, 700, 10.1177/096032719401301009 · DOI
  23. Hodgson A. A, 1979, Asbestos: properties, applications and hazards, 67
  24. McConnell E. E., 2002, Inhal. Toxicol., 14, 263, 10.1080/08958370252809040 · DOI
  25. Morrow P. E, 1988, Fundam. Appl. Toxicol, 10, 369, 10.1016/0272-0590(88)90284-9 · DOI · Paper page
  26. Morrow P. E, 1992, Toxicol. Appl. Pharmacol., 113, 1, 10.1016/0041-008X(92)90002-A · DOI
  27. Muhle H., 1988, Ann. Occup. Hyg., 32, 141
  28. Muhle H., 1987, Ann. Occup. Hyg., 31, 755, 10.1093/annhyg/31.4B.755 · DOI
  29. Muhle H., 1988, Ann. Occup. Hyg., 32, 141, 10.1093/annhyg/32.inhaled_particles_VI.141 · DOI
  30. Oberdörster G, 1995, Regul. Toxicol. Pharmacol., 21, 123, 10.1006/rtph.1995.1017 · DOI · Paper page
  31. Oberdörster G, 1995, Regul. Toxicol. Pharmacol., 21, 233, 10.1006/rtph.1995.1034 · DOI
  32. Oberdörster G, 2002, Inhal. Toxicol, 14, 29, 10.1080/089583701753338622 · DOI · Paper page
  33. Oberdörster G., 1992, Exp. Lung. Res., 18, 87, 10.3109/01902149209020653 · DOI
  34. Rogers R. A., 1999, Environ. Health Perspect., 107, 367
  35. Stoeber W., 1970, Staub-Reinh. Luft., 30, 277
  36. U.S. Environmental Protection Agency, 2003, Report on the Peer Consultation Workshop to discuss a proposed protocol to assess asbestos-related risk
  37. Warheit D. B., 1992, Toxicol. Appl. Pharmacol., 116, 225, 10.1016/0041-008X(92)90302-9 · DOI
  38. World Health Organization, 1985, Reference methods for measuring airborne man-made mineral fibres (MMMF), WHO/EURO MMMF Reference Scheme, 4
  39. Wypych F., 2005, J. Colloid Interface Sci., 283, 107, 10.1016/j.jcis.2004.08.139 · DOI

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Metadata

Authors
Bernstein, D. M., Rogers, R., Smith, P., & Chevalier, J.
Venue
Inhalation Toxicology
Publisher
Informa UK Limited
Published
2006-01
Volume
18
Issue
5
Pages
313-332
ISSN
  • 0895-8378
  • 1091-7691
DOI
10.1080/08958370500515871
Cited by
21
References
2
Language
en

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CoChat. (2026). Citation check: The Toxicological Response of Brazilian Chrysotile Asbestos: A Multidose Subchronic 90-Day Inhalation Toxicology Study with 92-Day Recovery to Assess Cellular and Pathological Response. https://app.cochat.ai/papers/10.1080/08958370500515871
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Bernstein, D. M., Rogers, R., Smith, P., & Chevalier, J. (2006). The Toxicological Response of Brazilian Chrysotile Asbestos: A Multidose Subchronic 90-Day Inhalation Toxicology Study with 92-Day Recovery to Assess Cellular and Pathological Response. Inhalation Toxicology. https://doi.org/10.1080/08958370500515871