Heat exposure and chronic kidney disease: a temporal link in a Taiwanese agricultural county
Abstract
Heat stress-related kidney injury has drawn public health attention. This study explored the temporal relationships between impaired kidney function and preceding outdoor heat exposure Taiwan. Data of participants collected through a health screening program was used to assess the association between chronic kidney disease (CKD) and average ambient temperature with various time lag structures. A total of 1,243 CKD cases and 38,831 non-CKD participants were included in the study. After adjusting for demographic, socioeconomic, lifestyle factors, and comorbidities, CKD was positively associated with the ambient temperature within 1-9 months. The 9-month average ambient temperature yielded the highest odds ratio of CKD (OR = 1.22; 95% CI = 1.09-1.37). Furthermore, females and farmers were found to be more vulnerable to CKD risk after outdoor heat exposure. These findings suggest that the prevention of heat stress-related kidney injury should consider relevant time frames and focus on vulnerable populations.
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Cites
KDIGO 2024 clinical practice guideline for the evaluation and management of chronic kidney disease
Stevens, P. E., Ahmed, S. B., Carrero, J. J., Foster, B., Francis, A., Hall, R. K., Herrington, W. G., Hill, G., Inker, L. A., Kazancıoğlu, R., et al. (2024) · Kidney International · doi:10.1016/j.kint.2023.10.018 · Cited by 8,530 · see citing works
Mortality risk attributable to high and low ambient temperature: a multicountry observational study
Gasparrini, A., Guo, Y., Hashizume, M., Lavigne, E., Zanobetti, A., Schwartz, J., Tobias, A., Tong, S., Rocklöv, J., Forsberg, B., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(14)62114-0 · Cited by 2,965 · see citing works
Pathophysiology of Acute Kidney Injury
Basile, D. P., Anderson, M. D., & Sutton, T. A. (2012) · Comprehensive physiology · doi:10.1002/cphy.c110041 · Cited by 1,115 · see citing works
Modeling exposure–lag–response associations with distributed lag non‐linear models
Gasparrini, A. (2013) · Statistics in Medicine · doi:10.1002/sim.5963 · Cited by 839 · see citing works
Heat stress in older individuals and patients with common chronic diseases
Kenny, G. P., Yardley, J., Brown, C., Sigal, R. J., & Jay, O. (2010) · Canadian Medical Association Journal · doi:10.1503/cmaj.081050 · Cited by 771 · see citing works
Bunker, A., Wildenhain, J., Vandenbergh, A., Henschke, N., Rocklöv, J., Hajat, S., & Sauerborn, R. (2016) · EBioMedicine · doi:10.1016/j.ebiom.2016.02.034 · Cited by 651 · see citing works
The effect of weather on respiratory and cardiovascular deaths in 12 U.S. cities.
Braga, A. L. F., Zanobetti, A., & Schwartz, J. D. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.02110859 · Cited by 618 · see citing works
Modeling the Wet Bulb Globe Temperature Using Standard Meteorological Measurements
Liljegren, J. C., Carhart, R. A., Lawday, P., Tschopp, S., & Sharp, R. (2008) · Journal of Occupational and Environmental Hygiene · doi:10.1080/15459620802310770 · Cited by 404 · cited 1× · see citing works
“…such as humidity, wind, and sun exposure, we further calculated wet bulb globe temperature (WBGT) from air temperature, dew point temperature, solar radiation, and wind speed using an R package implementation (https://github.com/anacv/ HeatStress) of the Liljegren formula (Liljegren et al. 2008).”
MethodChronic Kidney Disease of Unknown Cause in Agricultural Communities
Johnson, R. J., Wesseling, C., & Newman, L. S. (2019) · New England Journal of Medicine · doi:10.1056/nejmra1813869 · Cited by 376 · see citing works
Fructokinase activity mediates dehydration-induced renal injury
Jimenez, C. A. R., Ishimoto, T., Lanaspa, M. A., Rivard, C. J., Nakagawa, T., Ejaz, A. A., Cicerchi, C., Inaba, S., Le, M. T., Miyazaki, M., et al. (2013) · Kidney International · doi:10.1038/ki.2013.492 · Cited by 271 · see citing works
Decreased Kidney Function Among Agricultural Workers in El Salvador
Peraza, S., Wesseling, C., Aragón, A., Leiva, R., Gárcía-Trabanino, R., Torres, C., Jakobsson, K., Elinder, C. G., & Hogstedt, C. (2012) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2011.11.039 · Cited by 266 · see citing works
Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka
Athuraliya, N. T. C., Abeysekera, T. D. J., Amerasinghe, P., et al. (2011) · Kidney International · doi:10.1038/ki.2011.258 · Cited by 242 · see citing works
Samoli, E., Stafoggia, M., Rodopoulou, S., Ostro, B. D., Declercq, C., Alessandrini, E., Díaz, J., Karanasiou, A., Kelessis, A. G., Tertre, A. L., et al. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1206124 · Cited by 234 · see citing works
Hsu, C., Hwang, S., Wen, C.-P., Chang, H., Chen, T., Shiu, R.-S., Horng, S.-S., Chang, Y.-K., & Yang, W. (2006) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2006.07.018 · Cited by 207 · see citing works
Individual Responses to Heat Stress: Implications for Hyperthermia and Physical Work Capacity
Foster, J., Hodder, S., Lloyd, A. B., & Havenith, G. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.541483 · Cited by 159 · see citing works
Occupational heat stress and economic burden: A review of global evidence
Borg, M., Xiang, J., Anikeeva, O., Pisaniello, D., Hansen, A. L., Zander, K. K., Dear, K. B. G., Sim, M. R., & Bi, P. (2021) · Environmental Research · doi:10.1016/j.envres.2021.110781 · Cited by 149 · see citing works
Nanayakkara, S., Senevirathna, L., Abeysekera, T. D. J., et al. (2013) · Journal of Occupational Health · doi:10.1539/joh.13-0172-oa · Cited by 144 · see citing works
Chapman, C. L., Johnson, B. D., Parker, M., Hostler, D., Pryor, R. R., & Schlader, Z. (2020) · Temperature · doi:10.1080/23328940.2020.1826841 · Cited by 143 · see citing works
Hansson, E., Glaser, J. R., Jakobsson, K., Weiss, I., Wesseling, C., Lucas, R. A. I., LEE, J. K. W., Ekström, U., Wijkström, J., Bodin, T., et al. (2020) · Nutrients · doi:10.3390/nu12061639 · Cited by 129 · see citing works
Mortality Displacement as a Function of Heat Event Strength in 7 US Cities
Saha, M. V., Davis, R. E. L., & Hondula, D. M. (2013) · American Journal of Epidemiology · doi:10.1093/aje/kwt264 · Cited by 116 · see citing works
Short-term air pollution exposure aggravates Parkinson’s disease in a population-based cohort
Lee, H., Myung, W., Kim, D. K., Kim, S. E., Kim, C. T., & Kim, H. (2017) · Scientific Reports · doi:10.1038/srep44741 · Cited by 114 · see citing works
Lin, S., Hsu, W.-H., Van Zutphen, A. R., Saha, S., Luber, G., & Hwang, S.-A. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104728 · Cited by 105 · see citing works
Wondmagegn, B. Y., Xiang, J., Williams, S. S., Pisaniello, D., & Bi, P. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.11.479 · Cited by 101 · see citing works
Workload and cross-harvest kidney injury in a Nicaraguan sugarcane worker cohort
Hansson, E., Glaser, J. R., Weiss, I., Ekström, U., Apelqvist, J., Hogstedt, C., Peraza, S., Lucas, R. A. I., Jakobsson, K., Wesseling, C., et al. (2019) · Occupational and Environmental Medicine · doi:10.1136/oemed-2019-105986 · Cited by 100 · see citing works
Van Someren, E. J. W. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00557.2006 · Cited by 89 · see citing works
Sorensen, C. J., Butler-Dawson, J., Dally, M. J., Krisher, L. K., Griffin, B. R., Johnson, R. J., Lemery, J. M., Asensio, C., Tenney, L., & Newman, L. S. (2018) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0000000000001529 · Cited by 86 · see citing works
Economic Burden of Hospitalizations for Heat-Related Illnesses in the United States, 2001–2010
Schmeltz, M. T., Petkova, E. P., & Gamble, J. L. (2016) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph13090894 · Cited by 78 · see citing works
High Temperatures and Kidney Disease Morbidity: A Systematic Review and Meta-analysis
Lee, W.-S., Kim, W., Lim, Y., & Hong, Y. (2018) · Journal of Preventive Medicine and Public Health · doi:10.3961/jpmph.18.149 · Cited by 70 · see citing works
Experimental heat stress nephropathy and liver injury are improved by allopurinol
Roncal-Jiménez, C. A., Sato, Y., Milagres, T., Andrés-Hernando, A., García, G., Bjornstad, P., Butler-Dawson, J., Sorensen, C. J., Newman, L. S., Krisher, L. K., et al. (2018) · American Journal of Physiology-Renal Physiology · doi:10.1152/ajprenal.00543.2017 · Cited by 60 · see citing works
Wu, P.-C., Lin, C., Lung, S. C., et al. (2010) · Occupational and Environmental Medicine · doi:10.1136/oem.2010.056168 · Cited by 58 · see citing works
Risk of heatstroke in healthy elderly during heatwaves: A thermoregulatory modeling study
Ou, Y., Wang, F., Zhao, J., & Deng, Q. (2023) · Building and Environment · doi:10.1016/j.buildenv.2023.110324 · Cited by 54 · see citing works
Let’s take the heat out of the CKDu debate: more evidence is needed
Pearce, N., & Caplin, B. (2019) · Occupational and Environmental Medicine · doi:10.1136/oemed-2018-105427 · Cited by 51 · see citing works
Adeyeye, T. E., Insaf, T. Z., Al‐Hamdan, M. Z., Nayak, S. G., Stuart, N., DiRienzo, S., & Crosson, W. L. (2019) · Environmental Health · doi:10.1186/s12940-019-0467-5 · Cited by 46 · see citing works
Treed distributed lag nonlinear models
Mork, D., & Wilson, A. (2020) · Biostatistics · doi:10.1093/biostatistics/kxaa051 · Cited by 41 · see citing works
Sánchez‐Lozada, L. G., García‐Arroyo, F. E., Gonzaga, G., et al. (2018) · American Journal of Nephrology · doi:10.1159/000494663 · Cited by 34 · see citing works
González-Quiroz, M., Camacho, A., Faber, D., Aragón, A., Wesseling, C., Glaser, J. R., Blond, J. S. L., Smeeth, L. L., Nitsch, D., Pearce, N. E., et al. (2017) · BMC Nephrology · doi:10.1186/s12882-016-0422-4 · Cited by 28 · see citing works
Aguilar-Ramirez, D. J., Raña-Custodio, A., Villa, A. R., Rubilar, X., Olvera, N., Escobar, A., Johnson, R. J., Sánchez‐Lozada, L. G., Obrador, G. T., & Madero, M. (2020) · Nephrology Dialysis Transplantation · doi:10.1093/ndt/gfaa041 · Cited by 26 · see citing works
Dally, M. J., Butler-Dawson, J., Johnson, R. J., et al. (2020) · Kidney International Reports · doi:10.1016/j.ekir.2020.06.032 · Cited by 24 · see citing works
Chang, J. C.-J., & Yang, H. (2021) · Occupational and Environmental Medicine · doi:10.1136/oemed-2021-107369 · Cited by 17 · see citing works
Self-citationZafirah, Y., Lin, Y., Andhikaputra, G., Sung, F., Deng, L.-W., & Wang, Y.-C. (2022) · Atmospheric Environment · doi:10.1016/j.atmosenv.2022.119317 · Cited by 12 · see citing works
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Goswami, M., Jain, S., Alam, T., Deifalla, A. F., Ragab, A. E., & Khargotra, R. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1215706 · Cited by 33 · see citing works
- Authors
- Chang, C.-J., Chi, C.-Y., & Yang, H.-Y.
- Affiliations
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
- Corresponding author
- Yang, Hsiao-Yu
- Venue
- International Journal of Environmental Health Research
- Publisher
- Informa UK Limited
- Published
- 2023-06-15
- Volume
- 34
- Issue
- 3
- Pages
- 1511-1524
- ISSN
- 0960-3123 (ISSN-L)
- 1369-1619
- OpenAlex
- W4380739314
- Cited by
- 5
- References
- 40
- Citations by year
- 2026: 2 · 2024: 1 · 2023: 2
- FWCI
- 0.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Environmental Health Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Innovation and Policy Center for Population Health and Sustainable Environment (Population Health Research Center, PHRC), College of Public Health, National Taiwan University
- National Taiwan University Higher Education Sprout Project (112L900403)
- within the framework of the Higher Education Sprout Project by the Ministry of Education (MOE) in Taiwan
- Ministry of Science and Technology, Taiwan (MOST 109-2314-B-002-166-MY3)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Climate Change and Health Impacts
- Health Sciences › Medicine › Physiology › Thermoregulation and physiological responses
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Effects of Environmental Stressors on Livestock
- Keywords
- chronic kidney disease, heat exposure, heat stress, ambient temperature, time delay, farmers, sex differences, vulnerable populations
- MeSH terms
- Female, Humans, Kidney, Taiwan, Comorbidity, Heat Stress Disorders, Renal Insufficiency, Chronic
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