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Cited by 338

The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.

Anti‐inflammatory actions of acupuncture

Open access
Zijlstra, Freek J., van den Berg-de Lange, Ineke, Huygen, Frank J. P. M., Klein, Jan·2003·Mediators of Inflammation

Abstract

Acupuncture has a beneficial effect when treating many diseases and painful conditions, and therefore is thought to be useful as a complementary therapy or to replace generally accepted pharmacological intervention. The attributive effect of acupuncture has been investigated in inflammatory diseases, including asthma, rhinitis, inflammatory bowel disease, rheumatoid arthritis, epicondylitis, complex regional pain syndrome type 1 and vasculitis. Large randomised trials demonstrating the immediate and sustained effect of acupuncture are missing. Mechanisms underlying the ascribed immunosuppressive actions of acupuncture are reviewed in this communication. The acupuncture‐controlled release of neuropeptides from nerve endings and subsequent vasodilative and anti‐inflammatory effects through calcitonine gene‐related peptide is hypothesised. The complex interactions with substance P, the analgesic contribution of β‐endorphin and the balance between cell‐specific pro‐inflammatory and anti‐inflammatory cytokines tumour necrosis factor‐α and interleukin‐10 are discussed.

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Metadata

Authors
Zijlstra, F. J., van den Berg-de Lange, I., Huygen, F. J. P. M., & Klein, J.
Venue
Mediators of Inflammation
Publisher
Wiley
Published
2003-01
Volume
12
Issue
2
Pages
59-69
ISSN
  • 0962-9351 (ISSN-L)
  • 1466-1861
OpenAlex
W1968876514
Cited by
338
References
74
FWCI
11.52
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Anti‐inflammatory actions of acupuncture. https://app.cochat.ai/papers/10.1080/0962935031000114943
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Zijlstra, F. J., van den Berg-de Lange, I., Huygen, F. J. P. M., & Klein, J. (2003). Anti‐inflammatory actions of acupuncture. Mediators of Inflammation. https://doi.org/10.1080/0962935031000114943

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.