The DOI matches its Crossref record; 138 of the 138 references it cites were found in a registry or an index.
Dietary Antioxidant Compounds and Liver Health
Open accessAbstract
Chronic liver damage is a widespread pathology characterized by a progressive evolution from steatosis to chronic hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma. As the oxidative stress plays a central role in liver diseases pathogenesis and progression, the use of antioxidants have been proposed as therapeutic agents, as well as drug coadjuvants, to counteract liver damage. In this work in vitro and in vivo studies, with emphasis on humans and animals experiments, have been considered and reviewed according to antioxidant typologies. Great differences emerge as far as ingested doses, bioavailability and liver ability to accumulate the various compounds. Results available up to now suggest that lycopene-rich foods could be proposed in therapeutic treatment of some liver pathologies. On the other hand contradictory results have been obtained with alpha-tocopherol, beta-carotene and trans-resveratrol. Quercetin, silymarin, esculetin and thyme and rosemary among phenolic compounds need further studies.
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Cites
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
Jang, M., Cai, L., Udeani, G. O., Slowing, K. V., Thomas, C. F., Beecher, C. W. W., Fong, H. H. S., Farnsworth, N. R., Kinghorn, A. D., Mehta, R. G., et al. (1997) · Science · doi:10.1126/science.275.5297.218 · Cited by 4,935 · cited 1×
“The consensus of many in vitro- and of few in vivo- studies seems to be that micromolar amount of t-RES can counteract tumor initiation by anti-oxidant activities and by enzymatic carcinogen conversion, 57 , 58 , 59 and counteract tumor promotion by inhibiting cyclooxygenase and hydroperoxidase.”
BackgroundFruit, vegetables, and cancer prevention: A review of the epidemiological evidence
Block, G., Patterson, B., & Subar, A. (1992) · Nutrition and Cancer · doi:10.1080/01635589209514201 · Cited by 3,238
The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies
Flier, J. S., Underhill, L. H., & Friedman, S. L. (1993) · New England Journal of Medicine · doi:10.1056/nejm199306243282508 · Cited by 1,432
The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice
Moriya, K., Fujie, H., Shintani, Y., Yotsuyanagi, H., Tsutsumi, T., Ishibashi, K., Matsuura, Y., Kimura, S., Miyamura, T., & Koike, K. (1998) · Nature Medicine · doi:10.1038/2053 · Cited by 1,206
Oxidative stress, exercise, and antioxidant supplementation
Urso, M. L., & Clarkson, P. M. (2003) · Toxicology · doi:10.1016/s0300-483x(03)00151-3 · Cited by 1,075
Cytokines in Alcoholic and Nonalcoholic Steatohepatitis
Tilg, H., & Diehl, A. M. (2000) · New England Journal of Medicine · doi:10.1056/nejm200011163432007 · Cited by 948
Day, A. J., Cañada, F. J., Dı́az, J. C., Kroon, P. A., Mclauchlan, R., Faulds, C. B., Plumb, G. W., Morgan, M. R. A., & Williamson, G. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01211-4 · Cited by 819
Subbaramaiah, K., Chung, W. J., Michaluart, P., Telang, N., Tanabe, T., Inoue, H., Jang, M., Pezzuto, J. M., & Dannenberg, A. J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.34.21875 · Cited by 786
Oxidative stress-related molecules and liver fibrosis
Parola, M., & Robino, G. (2001) · Journal of Hepatology · doi:10.1016/s0168-8278(01)00142-8 · Cited by 783
Musso, G., Gambino, R., De Michieli, F., Cassader, M., Rizzetto, M., Durazzo, M., Fagà, E., Silli, B., & Pagano, G. (2003) · Hepatology · doi:10.1053/jhep.2003.50132 · Cited by 759
Cited by
Morisco, F., Vitaglione, P., Amoruso, D., Russo, B., Fogliano, V., & Caporaso, N. (2008) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2007.09.003 · Cited by 67
Self-citation
Metadata
- Authors
- Vitaglione, P., Morisco, F., Caporaso, N., & Fogliano, V.
- Venue
- Critical Reviews in Food Science and Nutrition
- Publisher
- Informa UK Limited
- Published
- 2004-12
- Volume
- 44
- Issue
- 7-8
- Pages
- 575-586
- ISSN
- 1040-8398 (ISSN-L)
- 1549-7852
- OpenAlex
- W2063854658
- Cited by
- 305
- References
- 138
- FWCI
- 3.30
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.