The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Protein Family of RNA Helicases
Abstract
RNA helicases represent a large family of proteins that have been detected in almost all biological systems where RNA plays a central role. They are ubiquitously distributed over a wide range of organisms and are involved in nuclear and mitochondrial splicing processes, RNA editing, rRNA processing, translation initiation, nuclear mRNA export, and mRNA degradation. RNA helicases are described as essential factors in cell development and differentiation, and some of them play a role in transcription and replication of viral single-stranded RNA genomes. Comparisons of the conserved sequences reveal a close relationship between them and suggest that these proteins might be derived from a common ancestor. Biochemical studies have revealed a strong dependence of the unwinding activity on ATP hydrolysis. Although RNA helicase activity has only been demonstrated for a few examples yet, it is generally believed that all members of the largest subgroups, the DEAD and DEAH box proteins, exhibit this activity.
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Cites
Gilbert, W. (1986) · Nature · doi:10.1038/319618a0 · Cited by 2,721
The assembly of prokaryotic ribosomes
Nierhaus, K. H. (1991) · Biochimie · doi:10.1016/0300-9084(91)90054-5 · Cited by 235
Cited by
Structural Basis for RNA Unwinding by the DEAD-Box Protein Drosophila Vasa
Sengoku, T., Nureki, O., Nakamura, A., Kobayashi, S., & Yokoyama, S. (2006) · Cell · doi:10.1016/j.cell.2006.01.054 · Cited by 573
The human VASA gene is specifically expressed in the germ cell lineage
Castrillon, D. H., Quade, B. J., Wang, T. Y., Quigley, C., & Crum, C. P. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.160274797 · Cited by 565
Requirement of DDX3 DEAD Box RNA Helicase for HIV-1 Rev-RRE Export Function
Yedavalli, V. S. R. K., Neuveut, C., Chi, Y.-H., Kleiman, L., & Jeang, K.-T. (2004) · Cell · doi:10.1016/j.cell.2004.09.029 · Cited by 549
SVITKIN, Y. V., PAUSE, A., HAGHIGHAT, A., PYRONNET, S., WITHERELL, G., BELSHAM, G. J., & SONENBERG, N. (2001) · RNA · doi:10.1017/s135583820100108x · Cited by 477
Wilson, J. E., Powell, M. J., Hoover, S. E., & Sarnow, P. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.14.4990-4999.2000 · Cited by 317
Metadata
- Authors
- Lüking, A., Stahl, U., & Schmidt, U.
- Venue
- Critical Reviews in Biochemistry and Molecular Biology
- Publisher
- Informa UK Limited
- Published
- 1998-01
- Volume
- 33
- Issue
- 4
- Pages
- 259-296
- ISSN
- 0045-6411 (ISSN-L)
- 1040-9238
- 1549-7798
- OpenAlex
- W1979533910
- Cited by
- 243
- References
- 2
- FWCI
- 1.28
- Type
- journal article
- Language
- en
- Open access
- closed
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