Optimization of Antioxidant Activity and Phenolic Compound Extraction Conditions from Red Seaweed ( Laurencia obtuse )
Abstract
Response surface methodology was used to investigate the effect of ultrasound-assisted extraction conditions including solvent:seaweed ratio (10:1–30:1), extraction temperature (30–50°C), and extraction time (30–60 min) on the total phenolic compounds and antioxidant activity of red seaweed (Laurencia obtuse) extracts. The optimum extraction parameters for maximum phenolic content were as follows: solvent:seaweed ratio, 30:1; extraction temperature, 50°C; and extraction time, 42.8 min. The experiment results showed that the solvent:seaweed ratio was the most significant parameter for the extraction. The optimum extraction conditions for maximum antioxidant activity were as follows: solvent:seaweed ratio, 24.3:1; extraction temperature, 45.3°C; and extraction time, 58 min. Under the above-mentioned conditions, the experimental total phenolic content and antioxidant activity value were 26.23 ± 0.75 mg GAE/g seaweed and 120.89 ± 0.81 TEAC, respectively, of seaweed tested, which are well compatible with the predicted contents.
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Antioxidant activity increased as TPC increased because phenolic compounds contribute most to antioxidant activity.
“Also, these studies showed that antioxidant activity increased as TPC increased because phenolic compounds contribute most to the antioxidant activity.”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [51]
According to Dang et al., temperature exhibited strongest influence on extraction yield and amount of extracted phenolic compounds, while Topuz et al. concluded solvent:seaweed ratio exhibited most influence on TPC.
“According to Dang et al. [49] the temperature exhibited the strongest influence on the extraction yield and amount of extracted phenolic compounds, while Topuz et al. [51] concluded that the solvent:seaweed ratio exhibited the most influence on TPC.”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [51]
Topuz et al. obtained higher content of polyphenols with 50 °C, 45 min, solvent:seaweed ratio 30:1 mL/g, and power 250 W.
“Topuz et al. [51] obtained a higher content of polyphenols with process parameters of 50 °C, time of 45 min, and solvent:seaweed ratio 30:1 mL/g, but with higher power of ultrasonic bath of 250 W.”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [51]
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References 24 · Cited by 47
- Authors
- Topuz, O. K., Gokoglu, N., Yerlikaya, P., Ucak, I., & Gumus, B.
- Affiliations
- Akdeniz University (TR)
- Corresponding author
- Topuz, Osman Kadir
- ORCID
- Topuz, Osman Kadir
- Venue
- Journal of Aquatic Food Product Technology
- Publisher
- Informa UK Limited
- Published
- 2015-01-27
- Volume
- 25
- Issue
- 3
- Pages
- 414-422
- ISSN
- 1049-8850 (ISSN-L)
- 1547-0636
- OpenAlex
- W2032827088
- Cited by
- 47
- References
- 24
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 8 · 2023: 5 · 2022: 6 · 2021: 6 · 2020: 8 · 2019: 6 · 2018: 2 · 2017: 1
- FWCI
- 1.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Aquatic Food Product Technology (publishedVersion)
- Funders
- Scientific Research Project Administration Unit of Akdeniz University
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
- Keywords
- Laurencia obtusa, red seaweed, ultrasound-assisted extraction, phenolic compounds, antioxidant activity, extraction optimization, extraction temperature, extraction time, seaweed extract
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