The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Gamma‐Hydroxybutyric Acid: Patterns of Use, Effects and Withdrawal
Abstract
Gamma‐hydroxybutyric acid (GHB) is gaining popularity as a drug of abuse. Reports of toxicity and lethality associated with GHB use have increased. This survey study was designed to identify patterns of GHB use, its effects, and withdrawal syndrome. A survey inquiring about the effects of GHB was administered to 42 users. The results showed that GHB was used to increased feelings of euphoria, relaxation, and sexuality. Adverse effects occurred more frequently in daily users and polydrug users than in occasional GHB users. Loss of consciousness was reported by 66% overdose by 28%% and amnesia by 13% of participants during GHB use and by 45% after GHB use. Three daily users developed a withdrawal syndrome that presented with anxiety, agitation, tremor, and delirium. Participants described GHB intoxication as having similarities to sedative‐hypnotic or alcohol intoxication. Regular use has been shown to produce tolerance and dependence. Participants dependent on GHB reported using multiple daily doses around the clock. High frequency users appeared at the greatest risk for developing withdrawal delirium and psychosis after abrupt discontinuation of GHB use.
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Van Cauter, E., Plat, L., Scharf, M. B., Leproult, R., Cespedes, S., L'Hermite-Balériaux, M., & Copinschi, G. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119587 · Cited by 234
Cited by
Wang, Y. G., Swick, T. J., Carter, L. P., Thorpy, M. J., & Benowitz, N. L. (2009) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.27549 · Cited by 271
Corkery, J. M., Loi, B., Claridge, H., Goodair, C., Corazza, O., Elliott, S., & Schifano, F. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.03.012 · Cited by 98
Metadata
- Authors
- Miotto, K., Darakjian, J., Basch, J., Murray, S., Zogg, J., & Rawson, R.
- Venue
- The American Journal on Addictions
- Publisher
- Wiley
- Published
- 2001-07
- Volume
- 10
- Issue
- 3
- Pages
- 232-241
- ISSN
- 1055-0496 (ISSN-L)
- 1521-0391
- OpenAlex
- W2120091443
- Cited by
- 191
- References
- 1
- FWCI
- 6.66
- Type
- journal article
- Language
- en
- Open access
- closed
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- Miotto, K., Darakjian, J., Basch, J., Murray, S., Zogg, J., & Rawson, R. (2001). Gamma‐Hydroxybutyric Acid: Patterns of Use, Effects and Withdrawal. The American Journal on Addictions. https://doi.org/10.1080/105504901750532111
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
