Cited by 80Substance Abuse Treatment and OutcomesSchizophrenia research and treatmentAlcohol Consumption and Health Effects

The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.

Disulfiram Treatment for Alcoholism in Severe Mental Illness

Mueser, Kim T., Noordsy, Douglas L., Fox, Lindy, Wolfe, Rosemarie·2003·The American Journal on Addictions

Abstract

Controlled research has shown that supervised disulfiram is an effective treatment for alcoholism. Despite this, little is known about the effects of disulfiram in persons with alcoholism and severe mental illness. We conducted comprehensive chart reviews on 33 patients with alcoholism and severe mental illness (70% schizophrenia or schizoaffective disorder) who had been prescribed disulfiram. Twenty‐one percent reported side effects from disulfiram, whereas significant psychiatric complications were not reported. Although 76%% of patients reported drinking while on disulfiram, only 28%o experienced negative reactions to alcohol. Sixty‐four percent of the patients saw a remission of alcoholism for at least one year during a three‐year follow‐up, and 30%o experienced a two‐year remission. Disulfiram treatment was associated with decreases in days hospitalized but not with changes in work status. The results suggest disulfiram may be a useful adjunctive treatment for alcoholism in patients with severe mental illness and that controlled research is needed to evaluate its effects in this population.

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Crossref · 10.1111/j.1521-0391.2003.tb00652.x

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Research works printed but not linked: 2

  1. Mueser KT, 1996, Dual Diagnosis of Major Mental Illness and Substance Abuse Disorder II: Recent Research and Clinical Implications. New Directions in Mental Health Services, Vol. 70, 33
  2. Mueser KT, 1995, Toolkit for Evaluating Substance Abuse in Persons with Severe Mental Illness

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Metadata

Authors
Mueser, K. T., Noordsy, D. L., Fox, L., & Wolfe, R.
Affiliations
  • Dartmouth College (US)
  • Dartmouth Psychiatric Research Center (US)
Corresponding author
Mueser, Kim T.
Venue
The American Journal on Addictions
Publisher
Wiley
Published
2003-05-06
Volume
12
Issue
3
Pages
242-252
ISSN
  • 1055-0496 (ISSN-L)
  • 1521-0391
OpenAlex
W2065550384
Cited by
80
References
30
Citations by year
2026: 1 · 2025: 2 · 2024: 1 · 2023: 1 · 2022: 4 · 2021: 2 · 2019: 6 · 2018: 2 · 2017: 1 · 2016: 2 · 2014: 5 · 2013: 2 · 2012: 3
FWCI
4.93
Type
journal article
Language
en
Open access
closed
Locations
  • American Journal on Addictions (publishedVersion)
  • PubMed (publishedVersion)
Funders
U.S. Public Health Service (10265)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
Keywords
disulfiram, alcoholism, severe mental illness, schizophrenia, schizoaffective disorder, alcoholism treatment, psychiatric complications, adverse effects, hospitalization, employment status, adjunctive therapy
MeSH terms
Absenteeism, Adult, Alcohol Deterrents, Alcoholism, Disulfiram, Female, Hospitalization, Humans, Male, Middle Aged, Psychotic Disorders, Retrospective Studies, Schizophrenia, Severity of Illness Index, Treatment Outcome

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CoChat. (2026). Citation check: Disulfiram Treatment for Alcoholism in Severe Mental Illness. https://app.cochat.ai/papers/10.1111/j.1521-0391.2003.tb00652.x
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Mueser, K. T., Noordsy, D. L., Fox, L., & Wolfe, R. (2003). Disulfiram Treatment for Alcoholism in Severe Mental Illness. The American Journal on Addictions. https://doi.org/10.1111/j.1521-0391.2003.tb00652.x