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Cited by 996

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Azo dyes and human health: A review

Chung, King-Thom·2016·Journal of Environmental Science and Health, Part C

Abstract

Synthetic azo dyes are widely used in industries. Gerhardt Domagk discovered that the antimicrobial effect of red azo dye Prontosil was caused by the reductively cleaved (azo reduction) product sulfanilamide. The significance of azo reduction is thus revealed. Azo reduction can be accomplished by human intestinal microflora, skin microflora, environmental microorganisms, to a lesser extent by human liver azoreductase, and by nonbiological means. Some azo dyes can be carcinogenic without being cleaved into aromatic amines. However, the carcinogenicity of many azo dyes is due to their cleaved product such as benzidine. Benzidine induces various human and animal tumors. Another azo dye component, p-phenylenediamine, is a contact allergen. Many azo dyes and their reductively cleaved products as well as chemically related aromatic amines are reported to affect human health, causing allergies and other human maladies.

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Metadata

Authors
Chung, K.-T.
Venue
Journal of Environmental Science and Health, Part C
Published
2016-09-16
Volume
34
Issue
4
Pages
233-261
ISSN
  • 1059-0501 (ISSN-L)
  • 1532-4095
OpenAlex
W2519022573
Cited by
996
References
1
FWCI
27.61
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Azo dyes and human health: A review. https://app.cochat.ai/papers/10.1080/10590501.2016.1236602
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Chung, K.-T. (2016). Azo dyes and human health: A review. Journal of Environmental Science and Health, Part C. https://doi.org/10.1080/10590501.2016.1236602

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