The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Folate-receptor-targeted delivery of docetaxel nanoparticles prepared by PLGA–PEG–folate conjugate
Abstract
For folate-receptor-targeted anticancer therapy, docetaxel (DTX) nanoparticles (NPs) were produced employing polylactide-co-glycolide-polyethylene glycol-folate (PLGA-PEG-FOL) conjugate. The FOL-conjugated di-block copolymer was synthesized by coupling the PLGA-PEG-NH(2) di-block copolymer with an activated folic acid. It was expected that FOL moieties were exposed on the micellar surface. The conjugates assisted in the formation of DTX NPs with an average size of 200 nm in diameter through an emulsification/solvent diffusion method. The FOL-targeted NPs showed a greater extent of intracellular uptake in FOL-receptor-positive cancer cells (SKOV3) in comparison with the non-targeted NPs, indicating that the FOL-receptor-mediated endocytosis mechanism could have a role in the cellular uptake of NPs. These results suggested that FOL-targeted DTX NPs could be a potentially useful delivery system for FOL-receptor-positive cancer cells.
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Cites
Formulation of functionalized PLGA-PEG Nanoparticles for in vivo targeted drug delivery
Cheng, J., Teply, B. A., Sherifi, I., Sung, J., Luther, G., Gu, F. X., Levy-Nissenbaum, E., Radovic-Moreno, A. F., Langer, R., & Farokhzad, O. C. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2006.09.047 · Cited by 1,273
Esmaeili, F., Ghahremani, M. H., Esmaeili, B., Khoshayand, M. R., Atyabi, F., & Dinarvand, R. (2008) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2007.07.038 · Cited by 159
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Cited by
Nicolas, J., Mura, S., Brambilla, D., Mackiewicz, N., & Couvreur, P. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35265f · Cited by 1,270
Properties and medical applications of polylactic acid: A review
Hamad, K., Kaseem, M., Yang, H. W., Deri, F., & Ko, Y. G. (2015) · Express Polymer Letters · doi:10.3144/expresspolymlett.2015.42 · Cited by 722
Extracellularly Activated Nanocarriers: A New Paradigm of Tumor Targeted Drug Delivery
Gullotti, E., & Yeo, Y. (2009) · Molecular Pharmaceutics · doi:10.1021/mp900090z · Cited by 473
Chitosan-Modified PLGA Nanoparticles with Versatile Surface for Improved Drug Delivery
Wang, Y., Li, P., & Kong, L. (2013) · AAPS PharmSciTech · doi:10.1208/s12249-013-9943-3 · Cited by 305
A novel 5-Fluorouracil targeted delivery to colon cancer using folic acid conjugated liposomes
Handali, S., Moghimipour, E., Rezaei, M., Ramezani, Z., Kouchak, M., Amini, M., Angali, K. A., Saremy, S., & Dorkoosh, F. A. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.09.128 · Cited by 154
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Metadata
- Authors
- Esmaeili, F., Ghahremani, M. H., Ostad, S. N., Atyabi, F., Seyedabadi, M., Malekshahi, M. R., Amini, M., & Dinarvand, R.
- Venue
- Journal of Drug Targeting
- Publisher
- Informa UK Limited
- Published
- 2008-01
- Volume
- 16
- Issue
- 5
- Pages
- 415-423
- ISSN
- 1026-7158 (ISSN-L)
- 1061-186X
- 1029-2330
- OpenAlex
- W2105812125
- Cited by
- 203
- References
- 2
- FWCI
- 5.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- Esmaeili, F., Ghahremani, M. H., Ostad, S. N., Atyabi, F., Seyedabadi, M., Malekshahi, M. R., Amini, M., & Dinarvand, R. (2008). Folate-receptor-targeted delivery of docetaxel nanoparticles prepared by PLGA–PEG–folate conjugate. Journal of Drug Targeting. https://doi.org/10.1080/10611860802088630
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