The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Platinum nanoparticle is a useful scavenger of superoxide anion and hydrogen peroxide
Abstract
Bimetallic nanoparticles consisting of gold and platinum were prepared by a citrate reduction method and complementarily stabilized with pectin (CP-Au/Pt). The percent mole ratio of platinum was varied from 0 to 100%. The CP-Au/Pt were alloy-structured. They were well dispersed in water. The average diameter of platinum nanoparticles (CP-Pt) was 4.7 +/- 1.5 nm. Hydrogen peroxide (H(2)O(2)) was quenched by CP-Au/Pt consisting of more than 50% platinum whereas superoxide anion radical (O(2)(-)) was quenched by any CP-Au/Pt. The CP-Au/Pt quenched these two reactive oxygen species in dose-dependent manners. The CP-Pt is the strongest quencher. The CP-Pt decomposed H(2)O(2) and consequently generated O(2) like catalase. The CP-Pt actually quenched O(2)(-) which was verified by a superoxide dismutase (SOD) assay kit. This quenching activity against O(2)(-) persisted like SOD. Taken together, CP-Pt may be a SOD/catalase mimetic which is useful for medical treatment of oxidative stress diseases.
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Direct evidence for catalase and peroxidase activities of ferritin–platinum nanoparticles
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Metadata
- Authors
- Kajita, M., Hikosaka, K., Iitsuka, M., Kanayama, A., Toshima, N., & Miyamoto, Y.
- Venue
- Free Radical Research
- Publisher
- Informa UK Limited
- Published
- 2007-01
- Volume
- 41
- Issue
- 6
- Pages
- 615-626
- ISSN
- 1029-2470 (ISSN-L)
- 1071-5762
- OpenAlex
- W2068631906
- Cited by
- 301
- References
- 31
- FWCI
- 5.67
- Type
- journal article
- Language
- en
- Open access
- closed
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