The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Strong increase in total delta-THC in cannabis preparations sold in Dutch coffee shops
Abstract
The total concentration of THC has been monitored in cannabis preparations sold in Dutch coffee shops since 1999. This annual monitoring was issued by the Ministry of Health after reports of increased potency. The level of the main psychoactive compound, Delta9-tetrahydrocannabinol (THC), is measured in marijuana and hashish. A comparison is made between imported and Dutch preparations, and between seasons. Samples of cannabis preparations from randomly selected coffee shops were analyzed using gas chromatography (GC-FID) for THC, CBD and CBN. In 2004, the average THC level of Dutch home-grown marijuana (Nederwiet) (20.4% THC) was significantly higher than that of imported marijuana (7.0% THC). Hashish derived from Dutch marijuana (Nederhasj) contained 39.3% THC in 2004, compared with 18.2% THC in imported hashish. The average THC percentage of Dutch marijuana, Dutch hashish and imported hashish was significantly higher than in previous years. It nearly doubled over 5 years. During this period, the THC percentage in imported marijuana remained unchanged. A higher price had to be paid for cannabis with higher levels of THC. Whether the increase in THC levels causes increased health risks for users can only be concluded when more data are available on adjusted patterns of use, abuse liability, bioavailability and levels of THC in the brain.
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Cites
Passing, H., & Bablok, W. (1983) · cclm · doi:10.1515/cclm.1983.21.11.709 · Cited by 1,513 · cited 2×
“To compare the results from the different laboratories, a Bablok-Passing analysis for linear regression was performed (Passing and Bablok, 1983).”
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Cited by
Mehmedic, Z., Chandra, S., Slade, D., Denham, H., Foster, S., Patel, A. S., Ross, S. A., Khan, I. A., & ElSohly, M. A. (2010) · Journal of Forensic Sciences · doi:10.1111/j.1556-4029.2010.01441.x · Cited by 475
New trends in cannabis potency in USA and Europe during the last decade (2008–2017)
Chandra, S., Radwan, M. M., Majumdar, C. G., Church, J. C., Freeman, T. P., & ElSohly, M. A. (2019) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-019-00983-5 · Cited by 469
Phytocannabinoids as novel therapeutic agents in {CNS} disorders.
Hill, A. J., Williams, C. M., Whalley, B. J., & Stephens, G. J. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2011.09.002 · Cited by 312
A systematic review of the antipsychotic properties of cannabidiol in humans
Iseger, T. A., & Bossong, M. G. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2015.01.033 · Cited by 261
Tortoriello, G., Morris, C. V., Alpar, A., Fuzik, J., Shirran, S. L., Calvigioni, D., Keimpema, E., Botting, C. H., Reinecke, K., Herdegen, T., et al. (2014) · The EMBO Journal · doi:10.1002/embj.201386035 · Cited by 255
Metadata
- Authors
- Pijlman, F., Rigter, S., Hoek, J., Goldschmidt, H., & Niesink, R.
- Venue
- Addiction Biology
- Publisher
- Wiley
- Published
- 2005-06
- Volume
- 10
- Issue
- 2
- Pages
- 171-180
- ISSN
- 1355-6215 (ISSN-L)
- OpenAlex
- W2137149172
- Cited by
- 168
- References
- 1
- FWCI
- 2.29
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pijlman, F., Rigter, S., Hoek, J., Goldschmidt, H., & Niesink, R. (2005). Strong increase in total delta-THC in cannabis preparations sold in Dutch coffee shops. Addiction Biology. https://doi.org/10.1080/13556210500123217
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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