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Subjective health status assessment: evaluation of the Italian version of the SF-12 Health Survey. Results from the MiOS Project
Abstract
BACKGROUND: SF-12 is a generic short form health survey, developed in the USA from the original SF-36. It produces two summary measures evaluating physical and mental self-perceived health that are interchangeable with those from the SF-36. SF-12 has been successfully tested in nine Western European countries on large samples of the general population, where it has proved its brevity, comprehensiveness, reliability, validity and cross-cultural applicability. The present analysis directly assesses the SF-12 for the first time in various Italian settings, including the general population and specific patient groups. METHODS: Data for this report were collected from five different samples; in four of them the SF-12 was used as a 'stand-alone' instrument, while in the other one (used as the reference) it was embedded in the SF-36. Descriptive statistics, Spearman's correlation coefficients, confirmatory factor analysis, ordinal uni- and multi-variate least squares regression model and covariance analysis were used to evaluate the summary measures in each sample, and across relevant subgroups. Studies were ordered according to the expected deviance, from the 'normal' health status of the reference group to the sample with the expected highest level of illness. RESULTS: Overall, more than 11,000 subjects were evaluated. Response rates ranged from 63 to 100%, while missing items accounted only for 0.2-8.2% of all items. Uni- and multi-variate analyses showed a positive association between both physical component summary (PCS) and mental component summary (MCS) scores and their respective items in all examined samples. MCS scores were fairly similar across all samples, with the only exception being patients recently discharged from hospital, whose subjective mental health perception was higher than expected and the highest of all (52.2). Finally, we found a substantial impact of ageing on physical health perception, while the MCS was shown to be less sensitive to the age effect. CONCLUSIONS: This analysis shows that the SF-12 has good validity, while some issues related to its most appropriate mode of administration and target groups might require further attention.
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“The Italian version of the SF-12 showed good content, construct, and criterion validity [31].”
From Psychological variables associated with quality of life in patients with head and neck cancer: the role of body image distress (2022) · cites this paper as [31]
In the citing paper
“Health-related quality of life and sexual functioning were measured with the use of widely used and reliable scales.”
From A stepped-care approach to symptomatic endometriosis management: A participatory research initiative (2018) · cites this paper as [65]
In the citing paper
“The clinical validity and internal consistency of the SF-12 have been demonstrated in large samples in many countries, including Italy (53,65).”
From A stepped-care approach to symptomatic endometriosis management: A participatory research initiative (2018) · cites this paper as [65]
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Scalamonti, S., Pivetta, G., Schiavone, F. P., Magnante, M., Pompili, M., Vavallo, M., Annibale, B., & Lahner, E. (2026) · Nutrients · doi:10.3390/nu18111807
“Physical component summary (PCS) and mental component summary (MCS) scores were considered as an expression of good QoL when >44 and >46, respectively [30,31].”
Scalvini, S., Donati, V., Zanelli, E., Giudici, V., Viscardi, L., D’Isa, S., Trevisan, R., & Bernocchi, P. (2026) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2026.106981
Napolitano, D., Gonzalo, M. F. M., Cascio, A. L., Benedetti, F., Povoli, A., Sanità, T., Suriano, V., Lorenzon, G., Luongo, A., Zaetta, D., et al. (2026) · Quality of Life Research · doi:10.1007/s11136-026-04305-w
Meneguzzo, P., Gugliotta, A., Favaro, A., Montagnese, S., Bonato, M., Scala, A., Miscioscia, M., & Garolla, A. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1872006
“Mental health – related quality of life was assessed using the Mental Component Summary (MCS) of the 12-Item Short Form Health Survey (SF-12) (25, 26).”
Donati, A., Giola, F., Privitera, G., Barbàra, G., Dridi, D., Ottolini, F. L., Buggio, L., Biciuffi, R., Parazzini, F., & Chiaffarino, F. (2026) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2026.115381
Sancassiani, F., Kalcev, G., Pintus, E., Lorrai, S., Cantone, E., Madeddu, C., Mulas, O., Caocci, G., Machado, S. E. D. C., Cruciata, M., et al. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15166354
“The Italian version of the SF-12 has demonstrated satisfactory reliability and construct validity for the assessment of physical and mental health-related quality of life [36].”
Ripari, C., Cilluffo, S., Bassola, B., Caruso, R., Terzoni, S., & Lusignani, M. (2026) · Nursing Reports · doi:10.3390/nursrep16090300
“The instrument provides two standardized summary scores, namely the Physical Component Summary (PCS) and the Mental Component Summary (MCS), calculated using standard scoring algorithms [5,18].”
InfluentialManzo, R., Fiorentino, G., Gaeta, A. M., Coppola, A., Spirito, V. D., Lanza, M., Mirizzi, A. I., Ferrarotti, I., Gatta, N., & Annunziata, A. (2026) · Pulmonology · doi:10.1080/25310429.2026.2737011
Metadata
- Authors
- Kodraliu, P. M.
- Venue
- Journal of Epidemiology and Biostatistics
- Publisher
- Informa UK Limited
- Published
- 2001-05-01
- Volume
- 6
- Issue
- 3
- Pages
- 305-316
- ISSN
- 1359-5229 (ISSN-L)
- OpenAlex
- W2160679825
- Cited by
- 209
- References
- 0
- Citations by year
- 2026: 17 · 2025: 17 · 2024: 18 · 2023: 18 · 2022: 16 · 2021: 20 · 2020: 15 · 2019: 15 · 2018: 9 · 2017: 7 · 2016: 6 · 2015: 4 · 2014: 7 · 2013: 4 · 2012: 1
- FWCI
- 3.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Epidemiology and Biostatistics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Keywords
- SF-12 Health Survey, self-rated health, Italian adaptation, SF-36, physical component summary, mental component summary, psychometric validation, cross-cultural adaptation, hospital discharge, patient-reported outcomes, questionnaire administration mode
- MeSH terms
- Adolescent, Adult, Aged, Cross-Sectional Studies, Female, Health Status, Health Surveys, Humans, Italy, Male, Middle Aged, Surveys and Questionnaires, Regression Analysis, Reproducibility of Results
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