Event-based prospective memory is independently associated with self-report of medication management in older adults
Open accessAbstract
BACKGROUND: Identifying potentially modifiable risk factors for medication non-adherence in older adults is important in order to enhance screening and intervention efforts designed to improve medication-taking behavior and health outcomes. The current study sought to determine the unique contribution of prospective memory (PM) (i.e. 'remembering to remember') to successful self-reported medication management in older adults. METHODS: Sixty-five older adults with current medication prescriptions completed a comprehensive research evaluation of sociodemographic, psychiatric, and neurocognitive functioning, which included the memory for adherence to medication scale (MAMS), prospective and retrospective memory questionnaire (PRMQ), and a performance-based measure of PM that measured both semantically related and semantically unrelated cue-intention (i.e. when-what) pairings. RESULTS: A series of hierarchical regressions controlling for biopsychosocial, other neurocognitive, and medication-related factors showed that elevated complaints on the PM scale of the PRMQ and worse performance on an objective semantically unrelated event-based PM task were independent predictors of poorer medication adherence as measured by the MAMS. CONCLUSIONS: PM plays an important role in self-report of successful medication management among older adults. Findings may have implications for screening for older individuals 'at risk' of non-adherence, as well as the development of PM-based interventions to improve medication adherence and, ultimately, long-term health outcomes in older adults.
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Mild cognitive impairment in older adults is associated with poor medication adherence in most studies.
“Also, mild cognitive impairment (MCI) in older adults has been found to be associated with poor medication adherence in most studies.11–13”
From Effectiveness of eHealth interventions targeted to improve medication adherence among older adults with mild cognitive impairment: a protocol for a systematic review and meta-analysis (2022) · cites this paper as [13]
The Introduction says neurocognitive impairment is a recognized risk factor for medication non-adherence in older adults and cites several studies linking lower cognitive scores to non-adherence. It does not establish that clinically defined mild cognitive impairment (MCI) is associated with poor adherence in most studies; the Methods describe a sample without a stated MCI diagnosis. (LLM, conf=0.86)
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Self-citation
- Authors
- Woods, S. P., Weinborn, M., Maxwell, B. R., Gummery, A., Mo, K., Ng, A. R. J., & Bucks, R. S.
- Affiliations
- The University of Western Australia (AU)
- Corresponding author
- Woods, Steven Paul
- Venue
- Aging & Mental Health
- Publisher
- Informa UK Limited
- Published
- 2014-01-13
- Volume
- 18
- Issue
- 6
- Pages
- 745-753
- ISSN
- 1360-7863 (ISSN-L)
- 1364-6915
- PMC
- PMC4040152
- OpenAlex
- W2060225078
- Semantic Scholar
- af4b436fdb23974c2d4abb92b121471c528b9e8d
- Cited by
- 36
- References
- 43
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 4 · 2023: 1 · 2022: 5 · 2021: 4 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 3 · 2015: 1
- FWCI
- 2.78
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Aging & Mental Health (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Funders
- National Institute of Mental Health (R01MH073419, P30MH062512)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Keywords
- prospective memory, event-based prospective memory, medication adherence, medication non-adherence, older adults, adherence screening, cognitive aging
- MeSH terms
- Aged, Aged, 80 and over, Mental Disorders, Female, Humans, Male, Middle Aged, Retrospective Studies, Semantics, Western Australia, Medication Adherence, Self Report, Memory, Episodic
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