Psychotropic drug prescription for nursing home residents with dementia: prevalence and associations with non-resident-related factors
Open accessAbstract
OBJECTIVES: To determine psychotropic drug prescription rates in nursing home residents with dementia and to identify associations with the so far understudied psychosocial non-resident-related factors. METHOD: A cross-sectional, observational, exploratory design as part of PROPER I (PRescription Optimization of Psychotropic drugs in Elderly nuRsing home patients with dementia). Participants were 559 nursing home residents with dementia, 25 physicians, and 112 nurses in the Netherlands. Psychotropic drug prescription, non-resident-related and known resident-related variables were measured to operationalize the themes of our previous qualitative analysis. RESULTS: Fifty-six percent of residents were prescribed any psychotropic drug, 25% antipsychotics, 29% antidepressants, 15% anxiolytics, and 13% hypnotics, with large differences between the units. Multivariate multilevel regression analyses revealed that antipsychotic prescription was less likely with higher physicians' availability (odds ratio 0.96, 95% confidence interval 0.93-1.00) and that antidepressant prescription was more likely with higher satisfaction of nurses on resident contact (odds ratio 1.50, 95% confidence interval 1.00-2.25). Resident-related factors explained 6%-15% of the variance, resident- and non-resident-related factors together 8%-17%. CONCLUSION: Prescription rates for antipsychotics are similar compared to other countries, and relatively low for antidepressants, anxiolytics, and hypnotics. Our findings indicate that improvement of prescribing could provisionally best be targeted at resident-related factors.
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Rates of psychotropic prescribing are particularly high across care homes in Western Europe, where up to 63% of residents are prescribed at least one psychotropic drug.
“Rates of prescribing are particularly high across care homes, where studies in the Western Europe have shown that up to 63% of residents are prescribed at least one psychotropic drug [5–8].”
From Stakeholders' views on the use of psychotropic medication in older people: a systematic review (2022) · cites this paper as [7]
The Introduction describes psychotropic drugs as widely prescribed in nursing home residents with dementia. The Prevalence rates section reports 56% of residents in the Dutch study received at least one psychotropic drug, with rates reaching 75% at some nursing home locations. It does not report a 63% figure or establish that figure as an upper rate across Western European care homes; its study population was residents with dementia. (LLM, conf=0.86)
Experimental — accuracy not yet measuredThe findings of this review help explain the findings of previous studies that have shown high rates of inappropriate psychotropic prescribing in older people both in care homes and wider settings.
“The findings of this review help explain the findings of previous studies that have shown high rates of inappropriate psychotropic prescribing in older people both in care homes [4–7] and wider settings [83].”
From Stakeholders' views on the use of psychotropic medication in older people: a systematic review (2022) · cites this paper as [7]
The Introduction reports widespread psychotropic prescribing among nursing-home residents with dementia, and the Prevalence rates section reports that 56% of residents in this study received a psychotropic drug. Neither passage establishes that those prescriptions were inappropriate; this study measured prescription rates, not rates of inappropriate prescribing. The citation to Smeets is in the care-home group [4–7], not the separate citation [83] for wider settings. (LLM, conf=0.85)
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- Authors
- Smeets, C. H. W., Gerritsen, D. L., Zuidema, S. U., Teerenstra, S., van der Spek, K., Smalbrugge, M., & Koopmans, R. T. C. M.
- Affiliations
- Radboud University Medical Center (NL)
- University Medical Center Groningen (NL)
- Department of Primary and Community Care, Center for Family Medicine, Geriatric Care and Public Health, Radboud university medical center, Nijmegen, The Netherlands
- Amsterdam Public Health (NL)
- Corresponding author
- Smeets, Claudia H. W.
- ORCID
- Venue
- Aging & Mental Health
- Publisher
- Informa UK Limited
- Published
- 2017-07-20
- Volume
- 22
- Issue
- 9
- Pages
- 1244-1252
- ISSN
- 1360-7863 (ISSN-L)
- 1364-6915
- OpenAlex
- W2738083022
- Cited by
- 31
- References
- 46
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 2 · 2023: 3 · 2022: 5 · 2021: 6 · 2020: 5 · 2019: 2 · 2018: 2 · 2017: 1
- FWCI
- 1.65
- Type
- journal article
- Language
- en
- Update notices
- correction (2018-12-10)
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Aging & Mental Health (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion, cc-by)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion, other-oa)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion, cc-by-nc-nd)
- Radboud Repository (Radboud University) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Funders
- The Netherlands Organisation for Health Research (ZonMw) and Development (113101005)
- Topics
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Health Sciences › Health Professions › General Health Professions › Geriatric Care and Nursing Homes
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- psychotropic drugs, dementia, nursing home residents, antipsychotic prescribing, antidepressant prescribing, anxiolytic prescribing, hypnotic prescribing, physician availability, nursing satisfaction, prescribing optimization, long-term care
- MeSH terms
- Aged, Aged, 80 and over, Cross-Sectional Studies, Dementia, Female, Homes for the Aged, Humans, Male, Medical Staff, Netherlands, Nursing Homes, Nursing Staff, Practice Patterns, Physicians', Drug Prescriptions, Psychotropic Drugs, Prevalence
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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