Cited by 505Chronic Disease Management StrategiesPrimary Care and Health OutcomesPharmaceutical Practices and Patient Outcomes

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Multimorbidity in primary care: Prevalence and trend over the last 20 years

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Uijen, Annemarie A., van de Lisdonk, Eloy H.·2008·European Journal of General Practice

DOI 10.1080/13814780802436093

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Abstract

OBJECTIVE: To determine the prevalence of multimorbidity in primary care, by age, sex, and socio-economic class, and to analyse the trend in multimorbidity over the last 20 years. METHODS: We performed an observational study using data from the Continuous Morbidity Registration (CMR) Nijmegen. This registration includes approximately 13 500 enlisted patients. To study the distribution of multimorbidity by age, sex, and socio-economic class, we analysed all patients enlisted in the CMR in 2005. To analyse the trend of multimorbidity over time, we studied the prevalence of multimorbidity from 1985 to 2005. RESULTS: We found that increasing age, female sex, and low socio-economic class are associated with an increasing number of patients with multimorbidity. The prevalence of chronic diseases doubled between 1985 and 2005. The proportion of patients with four or more chronic diseases increased in this period by approximately 300%. CONCLUSION: The increasing amount of multimorbidity in primary care as well as the increasing number of chronic diseases per patient leads to more complex medical care. The general practitioner needs guidelines focusing on multimorbidity to support this care. The registration of chronic diseases by the general practitioner will become more complex and time-consuming.

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Multimorbidity in General Practice: Prevalence, Incidence, and Determinants of Co-Occurring Chronic and Recurrent Diseases
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Additional file 3 of Network of doctors for multimorbidity and diabetes — the NOMAD intervention: protocol for feasibility trial of multidisciplinary team conferences for people with diabetes and multimorbidity
Bugge, S. J., Henriksen, D. P., Damkier, P., Rahbek, M. T., Schousboe, K., Rothmann, M. J., Poulsen, M. K., Hansen, C., Nagarajah, S., Jensen, P. B., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26734356
Additional file 3 of Effect of socio-demographic and health factors on the association between multimorbidity and acute care service use: population-based survey linked to health administrative data
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Additional file 2 of Moving from “let’s fix them” to “actually listen”: the development of a primary care intervention for mental-physical multimorbidity
McKenzie, K. J., Fletcher, S. L., Pierce, D., & Gunn, J. M. (2021) · Figshare · doi:10.6084/m9.figshare.14361326
Additional file 1 of Effect of socio-demographic and health factors on the association between multimorbidity and acute care service use: population-based survey linked to health administrative data
Fisher, K. A., Griffith, L. E., Gruneir, A., Upshur, R., Perez, R., Favotto, L., Nguyen, F., Markle‐Reid, M., & Ploeg, J. (2021) · Figshare · doi:10.6084/m9.figshare.13565654
Additional file 3 of Measuring needs-based quality of life and self-perceived health inequity in patients with multimorbidity: investigating psychometric measurement properties of the MultiMorbidity Questionnaire (MMQ) using primarily Rasch models
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Nine keys for successful interprofessional collaboration Based on observing facilitators and barriers during different types of treatment meetings: A qualitative study
de Gans, S. T., Raijmann, R. C. M. A., Huijbers, M. F., Looman, N., van de Pol, M. H. J., van der Zwaard, B. C., Koek, H. L., Emmelot‐Vonk, M. H., & Keijsers, C. J. P. W. (2026) · PLoS ONE · doi:10.1371/journal.pone.0350554

Authors: Uijen, A. A., & van de Lisdonk, E. H.
Affiliations: Radboud University Medical Center (NL)
Corresponding author: Uijen, Annemarie A.
ORCID: Uijen, Annemarie A.
Venue: European Journal of General Practice
Publisher: Informa UK Limited
Published: 2008-01
Volume: 14
Issue: sup1
Pages: 28-32
ISSN: 1381-4788 (ISSN-L)
1751-1402
DOI: 10.1080/13814780802436093
OpenAlex: W2169722090
Cited by: 505
References: 13
Citations by year: 2026: 8 · 2025: 23 · 2024: 27 · 2023: 33 · 2022: 38 · 2021: 57 · 2020: 35 · 2019: 30 · 2018: 35 · 2017: 28 · 2016: 36 · 2015: 31 · 2014: 29 · 2013: 28 · 2012: 29
FWCI: 9.07
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: European Journal of General Practice (publishedVersion)
PubMed (publishedVersion)
BIBSYS Brage (BIBSYS (Norway)) (submittedVersion)
NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
Radboud Repository (Radboud University) (submittedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
Health Sciences › Medicine › Family Practice › Primary Care and Health Outcomes
Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
Keywords: multimorbidity, chronic disease, prevalence trends, primary care, socioeconomic class, age and sex differences, general practitioner workload, complex care
MeSH terms: Adolescent, Adult, Aged, Child, Preschool, Chronic Disease, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Morbidity, Netherlands, Primary Health Care, Registries, Social Class, Prevalence, Age Distribution, Sex Distribution, Young Adult

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Multimorbidity in primary care: Prevalence and trend over the last 20 years

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