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Multimorbidity in primary care: Prevalence and trend over the last 20 years
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OBJECTIVE: To determine the prevalence of multimorbidity in primary care, by age, sex, and socio-economic class, and to analyse the trend in multimorbidity over the last 20 years. METHODS: We performed an observational study using data from the Continuous Morbidity Registration (CMR) Nijmegen. This registration includes approximately 13 500 enlisted patients. To study the distribution of multimorbidity by age, sex, and socio-economic class, we analysed all patients enlisted in the CMR in 2005. To analyse the trend of multimorbidity over time, we studied the prevalence of multimorbidity from 1985 to 2005. RESULTS: We found that increasing age, female sex, and low socio-economic class are associated with an increasing number of patients with multimorbidity. The prevalence of chronic diseases doubled between 1985 and 2005. The proportion of patients with four or more chronic diseases increased in this period by approximately 300%. CONCLUSION: The increasing amount of multimorbidity in primary care as well as the increasing number of chronic diseases per patient leads to more complex medical care. The general practitioner needs guidelines focusing on multimorbidity to support this care. The registration of chronic diseases by the general practitioner will become more complex and time-consuming.
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“Fourth, adults are more likely to have comorbidities45, 46 that lead to immunodeficiencies and increase the risk of opportunistic infections.47”
From Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050 (2024) · cites this paper as [46]
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Metadata
- Authors
- Uijen, A. A., & van de Lisdonk, E. H.
- Affiliations
- Radboud University Medical Center (NL)
- Corresponding author
- Uijen, Annemarie A.
- ORCID
- Uijen, Annemarie A.
- Venue
- European Journal of General Practice
- Publisher
- Informa UK Limited
- Published
- 2008-01
- Volume
- 14
- Issue
- sup1
- Pages
- 28-32
- ISSN
- 1381-4788 (ISSN-L)
- 1751-1402
- OpenAlex
- W2169722090
- Cited by
- 505
- References
- 13
- Citations by year
- 2026: 8 · 2025: 23 · 2024: 27 · 2023: 33 · 2022: 38 · 2021: 57 · 2020: 35 · 2019: 30 · 2018: 35 · 2017: 28 · 2016: 36 · 2015: 31 · 2014: 29 · 2013: 28 · 2012: 29
- FWCI
- 9.07
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Journal of General Practice (publishedVersion)
- PubMed (publishedVersion)
- BIBSYS Brage (BIBSYS (Norway)) (submittedVersion)
- NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
- Radboud Repository (Radboud University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Family Practice › Primary Care and Health Outcomes
- Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
- Keywords
- multimorbidity, chronic disease, prevalence trends, primary care, socioeconomic class, age and sex differences, general practitioner workload, complex care
- MeSH terms
- Adolescent, Adult, Aged, Child, Preschool, Chronic Disease, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Morbidity, Netherlands, Primary Health Care, Registries, Social Class, Prevalence, Age Distribution, Sex Distribution, Young Adult
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