The DOI matches its Crossref record; 430 of the 431 references it cites were found in a registry or an index.
Polymeric micelles: authoritative aspects for drug delivery
Abstract
The generation of supramolecular architectures with well-defined structures and functionalities is recently garnering attraction. Self-assemblage of amphiphilic polymers leads to the formation of polymeric micelles that demonstrate unique set of characteristics such as excellent biocompatibility, low toxicity, enhanced blood circulation time, and solubilization of poorly water-soluble drugs. In this article, we provide an up-to-date review on important aspects of polymeric micelles. Critical factors for solubilization of hydrophobic drugs in the micellar core are discussed. Polymeric micelles can be used as 'smart' drug carriers for targeting certain areas of the body. Here, we have especially emphasized on the recent developments in the targetability of certain tissues such as cancerous tissues using polymeric micelles. Different stimuli exploited for creating stimuli-sensitive micelles are discussed comprehensively. Application of polymeric micelles in the photodynamic therapy is also meticulously described.
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“The hydrophilic part is usually composed of PEG (polyethylenglycole), but other polymers are also used such as poly(vinyl pyrrolidone), poly (acryloylmorpholine), or poly(trimethylene carbonate); the hydrophobic segment can be made up of poly(propylene oxide), or polyesters like poly(ε-caprolactone) or polymers and co-polymers of glycolic and lactic acids [36].”
From Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions (2021) · cites this paper as [36]
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“The most investigated administration route for micelles is the intravenous (i.v.) injection/infusion (mainly exploited for chemotherapy) [18,[47][48][49], but very interesting results in terms of improved drug bioavailability have also been reported following oral [31,50] and topical (ocular, nasal, buccal) [26,36,51,52] administration.”
From Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions (2021) · cites this paper as [36]
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Metadata
- Authors
- Kulthe, S. S., Choudhari, Y. M., Inamdar, N. N., & Mourya, V.
- Affiliations
- a Government College of Pharmacy , Aurangabad , 431005 , Maharashtra , India
- ORCID
- Inamdar, Nazma N.
- Venue
- Designed Monomers and Polymers
- Publisher
- Informa UK Limited
- Published
- 2012-07-02
- Volume
- 15
- Issue
- 5
- Pages
- 465-521
- ISSN
- 1385-772X (ISSN-L)
- 1568-5551
- OpenAlex
- W2070517405
- Cited by
- 235
- References
- 431
- Citations by year
- 2026: 16 · 2025: 17 · 2024: 23 · 2023: 28 · 2022: 44 · 2021: 33 · 2020: 25 · 2019: 11 · 2018: 11 · 2017: 3 · 2016: 2 · 2015: 3 · 2014: 7 · 2013: 12
- FWCI
- 2.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Designed Monomers & Polymers (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Surfactants and Colloidal Systems
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Keywords
- polymeric micelles, drug delivery, amphiphilic polymers, self-assembly, hydrophobic drug solubilization, targeted drug delivery, tumor targeting, stimuli-responsive micelles, photodynamic therapy, biocompatibility
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