Cited by 235Nanoparticle-Based Drug DeliverySurfactants and Colloidal SystemsAdvanced Drug Delivery Systems

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Polymeric micelles: authoritative aspects for drug delivery

Kulthe, Sushant S., Choudhari, Yogesh M., Inamdar, Nazma N., Mourya, Vishnukant·2012·Designed Monomers and Polymers

DOI 10.1080/1385772x.2012.688328

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Abstract

The generation of supramolecular architectures with well-defined structures and functionalities is recently garnering attraction. Self-assemblage of amphiphilic polymers leads to the formation of polymeric micelles that demonstrate unique set of characteristics such as excellent biocompatibility, low toxicity, enhanced blood circulation time, and solubilization of poorly water-soluble drugs. In this article, we provide an up-to-date review on important aspects of polymeric micelles. Critical factors for solubilization of hydrophobic drugs in the micellar core are discussed. Polymeric micelles can be used as 'smart' drug carriers for targeting certain areas of the body. Here, we have especially emphasized on the recent developments in the targetability of certain tissues such as cancerous tissues using polymeric micelles. Different stimuli exploited for creating stimuli-sensitive micelles are discussed comprehensively. Application of polymeric micelles in the photodynamic therapy is also meticulously described.

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Authors: Kulthe, S. S., Choudhari, Y. M., Inamdar, N. N., & Mourya, V.
Affiliations: a Government College of Pharmacy , Aurangabad , 431005 , Maharashtra , India
ORCID: Inamdar, Nazma N.
Venue: Designed Monomers and Polymers
Publisher: Informa UK Limited
Published: 2012-07-02
Volume: 15
Issue: 5
Pages: 465-521
ISSN: 1385-772X (ISSN-L)
1568-5551
DOI: 10.1080/1385772x.2012.688328
OpenAlex: W2070517405
Cited by: 235
References: 431
Citations by year: 2026: 16 · 2025: 17 · 2024: 23 · 2023: 28 · 2022: 44 · 2021: 33 · 2020: 25 · 2019: 11 · 2018: 11 · 2017: 3 · 2016: 2 · 2015: 3 · 2014: 7 · 2013: 12
FWCI: 2.85
Type: journal article
Language: en
Open access: closed
Locations: Designed Monomers & Polymers (publishedVersion)
Topics: Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Surfactants and Colloidal Systems
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Keywords: polymeric micelles, drug delivery, amphiphilic polymers, self-assembly, hydrophobic drug solubilization, targeted drug delivery, tumor targeting, stimuli-responsive micelles, photodynamic therapy, biocompatibility

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Polymeric micelles: authoritative aspects for drug delivery

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