Cited by 13Alzheimer's disease research and treatmentsProtein Kinase Regulation and GTPase SignalingAutophagy in Disease and Therapy

Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents

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Maestro, Ines, Madruga, Enrique, Boya, Patricia, Martínez, Ana·2023·Journal of Enzyme Inhibition and Medicinal Chemistry

Abstract

model of AD and ii) block mitophagy in a PRKN-independent manner, reinforcing the hypothesis of SGK1 inhibitors as neuroprotective chemical tools.

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Cited by

Sorted by citations

Authors
Maestro, I., Madruga, E., Boya, P., & Martínez, A.
Affiliations
  • Centro de Investigaciones, Biológicas Margarita Salas-CSIC
  • Consejo Superior de Investigaciones Científicas (ES)
Venue
Journal of Enzyme Inhibition and Medicinal Chemistry
Published
2023-01-13
Volume
38
Issue
1
Pages
2153841-2153841
ISSN
  • 1475-6366 (ISSN-L)
  • 1475-6374
OpenAlex
W4315928283
Cited by
13
References
3
Citations by year
2026: 2 · 2025: 5 · 2024: 5 · 2023: 1
FWCI
2.31
Type
journal article
Language
en
Open access
Locations
  • Journal of Enzyme Inhibition and Medicinal Chemistry (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CB18/05/00040)
  • Horizon 2020 Framework Programme (H2020-MSCA, 765912, PID2019, H2020-MSCA-ITN-2017, H2020-MSCA-ITN)
Topics
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Kinase Regulation and GTPase Signaling
  • Health Sciences › Medicine › Epidemiology › Autophagy in Disease and Therapy
Keywords
SGK1 inhibitor, structural families, neuroprotection, Alzheimer's disease, mitophagy, kinase inhibitors
MeSH terms
Apoptosis, Protein Serine-Threonine Kinases, Neuroprotective Agents

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